{"id":15781,"date":"2017-12-14T00:00:37","date_gmt":"2017-12-14T08:00:37","guid":{"rendered":"https:\/\/vermont.salk.edu\/?post_type=disclosure&p=15781"},"modified":"2018-10-04T10:46:51","modified_gmt":"2018-10-04T17:46:51","slug":"revealing-best-kept-secrets-proteins","status":"publish","type":"disclosure","link":"https:\/\/www.salk.edu\/zh\/news-release\/revealing-best-kept-secrets-proteins\/","title":{"rendered":"\u63ed\u793a\u86cb\u767d\u8d28\u7684\u79d8\u5bc6"},"content":{"rendered":"

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\u7248\u6743\uff1a\u8428\u514b\u7814\u7a76\u6240<\/figcaption><\/figure>\n

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\u201c\u6211\u7684\u4efb\u52a1\u662f\u627e\u51fa\u5982\u4f55\u53ea\u7b5b\u900930\u4e2a\u7a81\u53d8\u9175\u6bcd\u7ec6\u80de\uff0c\u800c\u4e0d\u662f30\u4e07\u4e2a\uff0c\u6765\u53d1\u73b0\u86cb\u767d\u8d28\u7684\u65b0\u6d3b\u6027\uff0c\u201d\u8be5\u8bba\u6587\u7684\u5171\u540c\u7b2c\u4e00\u4f5c\u8005Lubin\u8bf4\u9053\u3002\u53e6\u4e00\u4f4d\u5171\u540c\u7b2c\u4e00\u4f5c\u8005Timothy Tucey\u66fe\u662fLundblad\u5c0f\u7ec4\u7684\u535a\u58eb\u540e\u7814\u7a76\u5458\uff0c\u73b0\u5c31\u804c\u4e8e\u83ab\u7eb3\u4ec0\u5927\u5b66\u3002.<\/p>\n

\u4ed6\u4eec\u4e00\u8d77\u8f6c\u5411\u4e86\u4e00\u79cd\u540d\u4e3a Est1 \u7684\u86cb\u767d\u8d28\uff0c\u8fd9\u662f Lundblad \u5728 1989 \u5e74\u4f5c\u4e3a\u535a\u58eb\u540e\u7814\u7a76\u5458\u5728\u9175\u6bcd\u4e2d\u53d1\u73b0\u7684\u3002Est1 \u662f\u7aef\u7c92\u9176\uff08\u4e00\u79cd\u9176\uff09\u7684\u4e00\u4e2a\u4e9a\u57fa\uff0c\u7aef\u7c92\u9176\u53ef\u4ee5\u9632\u6b62\u67d3\u8272\u4f53\u672b\u7aef\u7684\u4fdd\u62a4\u6027\u5e3d\uff08\u79f0\u4e3a\u7aef\u7c92\uff09\u53d8\u5f97\u592a\u77ed\u3002\u4f5c\u4e3a\u7b2c\u4e00\u4e2a\u88ab\u53d1\u73b0\u7684\u7aef\u7c92\u9176\u4e9a\u57fa\uff0cEst1 \u5df2\u7ecf\u88ab\u8bb8\u591a\u7814\u7a76\u5c0f\u7ec4\u8fdb\u884c\u4e86\u6df1\u5165\u7814\u7a76\u3002.<\/p>\n

\u7d22\u5c14\u514b\u56e2\u961f\u7684\u65b9\u6cd5\u662f\u5411\u9175\u6bcd\u7ec6\u80de\u4e2d\u5f15\u5165\u4e00\u7ec4\u5c11\u91cf\u4f46\u7ecf\u8fc7\u5b9a\u5236\u7684\u7a81\u53d8\uff0c\u4ee5\u9009\u62e9\u6027\u5730\u7834\u574f\u7ec6\u80de Est1 \u86cb\u767d\u4e0a\u7684\u8868\u9762\u63a5\u89e6\u3002\u7136\u540e\uff0c\u8be5\u56e2\u961f\u5206\u6790\u7ec6\u80de\uff0c\u89c2\u5bdf\u5404\u79cd\u7a81\u53d8\u662f\u5426\u4ee5\u53ca\u6709\u4f55\u5f71\u54cd\u3002\u7279\u5b9a\u7a81\u53d8\u5f15\u8d77\u7684\u5f02\u5e38\u5c06\u8868\u660e\u672a\u7a81\u53d8\u7248\u672c\u7684\u4f5c\u7528\u3002\u4e3a\u6b64\uff0c\u4ed6\u4eec\u4f7f\u7528\u4e86\u4e00\u79cd\u9057\u4f20\u5b66\u6280\u5de7\uff0c\u5c06\u6bcf\u79cd\u7a81\u53d8\u86cb\u767d\u6ce8\u5165\u7ec6\u80de\uff0c\u5e76\u5bfb\u627e\u80fd\u591f\u5e72\u6270\u7ec6\u80de\u529f\u80fd\u7684\u7f55\u89c1\u7a81\u53d8\u86cb\u767d\uff0c\u56e0\u4e3a\u4ed6\u4eec\u5148\u524d\u7684\u7814\u7a76\u8868\u660e\uff0c\u8fd9\u4f1a\u4f18\u5148\u9776\u5411\u86cb\u767d\u8d28\u8868\u9762\u3002.<\/p>\n

\u9686\u5fb7\u5e03\u62c9\u5fb7\u7684\u56e2\u961f\u901a\u8fc7\u8fd9\u79cd\u65b9\u6cd5\u53d1\u73b0\u4e86 Est1 \u7684\u56db\u79cd\u529f\u80fd\u3002\u79d1\u5b66\u5bb6\u4eec\u53d1\u73b0\uff0c\u901a\u8fc7\u5bf9 Est1 \u8868\u9762\u6c28\u57fa\u9178\u8fdb\u884c\u7a81\u53d8\u5bfc\u81f4\u8fd9\u56db\u79cd\u529f\u80fd\u53d7\u635f\uff0c\u4f1a\u4ea7\u751f\u7aef\u7c92\u4e25\u91cd\u7f29\u77ed\u7684\u7ec6\u80de\uff0c\u8fd9\u8868\u660e Est1 \u4e0e\u7aef\u7c92\u9176\u590d\u5408\u7269\u7684\u63a5\u89e6\u5728\u5176\u4e2d\u53d1\u6325\u7740\u7279\u5b9a\u7684\u4f5c\u7528\u3002.<\/p>\n

\u201c\u8fd9\u79cd\u6280\u672f\u8ba9\u6211\u4eec\u611f\u5230\u5174\u594b\u7684\u662f\uff0c\u5b83\u53ef\u4ee5\u5e94\u7528\u4e8e\u591a\u79cd\u86cb\u767d\u8d28\uff0c\u201d\u4f26\u5fb7\u5e03\u62c9\u5fb7\u8bf4\u3002\u201c\u7279\u522b\u662f\uff0c\u8bb8\u591a\u6cbb\u7597\u836f\u7269\u4f9d\u8d56\u4e8e\u80fd\u591f\u63a5\u89e6\u86cb\u767d\u8d28\u8868\u9762\u7684\u4e00\u4e2a\u975e\u5e38\u7279\u5b9a\u7684\u4f4d\u7f6e\uff0c\u6211\u4eec\u6000\u7591\u8fd9\u79cd\u65b9\u6cd5\u53ef\u4ee5\u63ed\u793a\u8fd9\u4e00\u70b9\u3002\u201d<\/p>\n

\u5229\u7528\u8fd9\u79cd\u65b9\u6cd5\uff0c\u5979\u7684\u56e2\u961f\u5df2\u7ecf\u53d1\u73b0\u4e86\u4e00\u7ec4\u8c03\u63a7\u57fa\u56e0\u7ec4\u7a33\u5b9a\u6027\u7684\u86cb\u767d\u8d28\u7684\u65b0\u529f\u80fd\uff0c\u5e76\u4e14\u5df2\u7ecf\u7533\u8bf7\u4e86\u4e3a\u836f\u7269\u9776\u70b9\u7814\u7a76\u63d0\u4f9b\u8d44\u91d1\u7684\u8d44\u52a9\u3002.<\/p>\n

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