Salk Cancer Center

Members

Salk Institute for Biological Studies - Salk Cancer Center - Members

Members



Janelle Ayres

Associate Professor
NOMIS Center for Immunobiology and Microbial Pathogenesis
Helen McLoraine Developmental Chair

Areas of interest: inflammation and pathobionts in the gut microbiota
Disease models: pathobionts, colorectal cancer

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Jesse Dixon

Helmsley-Salk Fellow
Helmsley Center for Genomic Medicine


Areas of interest: 3d genomic control
Disease models: pediatric leukemia, colon cancer

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Joseph Ecker

Professor
Director, Genomic Analysis Laboratory
Howard Hughes Medical Institute Investigator
Salk International Council Chair in Genetics

Areas of interest: epigenomics of stem cells and cancer cells
Disease models: breast cancer

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Ronald Evans

Professor and Director
Gene Expression Laboratory
Howard Hughes Medical Institute Investigator
March of Dimes Chair in Molecular and Developmental Biology

Areas of interest: nuclear receptor function in metabolism and cancer
Disease models: pancreatic cancer, colon cancer, diabetes

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Rusty Gage

President
Professor
Laboratory of Genetics
Vi and John Adler Chair for Research on Age-Related Neurodegenerative Disease

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Diana Hargreaves

Assistant Professor
Molecular and Cell Biology Laboratory
Richard Heyman and Anne Daigle Endowed Development Chair

Areas of interest: BAF chromatin remodeling complex and the role of chromatin regulators in cancer
Disease models: BAF subunit mutant solid tumors such as medulloblastomas

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Martin Hetzer

Professor
Molecular and Cell Biology Laboratory
Jesse and Caryl Philips Foundation Chair

Areas of interest: nuclear pore protein function, micronuclei and cancer
Disease models: AML

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Patrick Hsu

Helmsley-Salk Fellow
Helmsley Center for Genomic Medicine


Areas of interest: CRISPR, genome engineering, RNA
Disease models: cancer and neurodegenerative disorders

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Tony Hunter

American Cancer Society Professor
Molecular and Cell Biology Laboratory
Renato Dulbecco Chair

Areas of interest: phosphorylation, ubiquitylation and sumoylation in cancer
Disease models: cancer kinome, pancreatic cancer, glioblastoma, prostate cancer

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Juan Carlos Izpisua Belmonte

Professor
Gene Expression Laboratory
Roger Guillemin Chair

Areas of interest: mechanisms underlying stem cell biology in cancer and regeneration
Disease models: IPS cells, glioblastoma, lung cancer, breast cancer

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Gerald Joyce

Professor
Jack H. Skirball Center for Chemical Biology and Proteomics

Areas of interest: RNA evolution, RNA biology
Disease models: high throughput screening and development of small molecules and biologic therapeutics

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Susan Kaech

Professor and Director
NOMIS Center for Immunobiology and Microbial Pathogenesis
NOMIS Chair

Areas of interest: T cell function, tumor immunology
Disease models: immune checkpoint inhibitors in model systems

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Jan Karlseder

Professor
Molecular and Cell Biology Laboratory
Donald and Darlene Shiley Chair

Areas of interest: telomere function and dysregulation in cancer cells
Disease models: combined treatment of cancer with mitotic inhibitors (Taxol, Velcade and Vinblastine) and PARP inhibitors

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Kuo-Fen Lee

Professor
Clayton Foundation Laboratories for Peptide Biology
Helen McLoraine Chair in Molecular Neurobiology

Areas of interest: integration of RTK and GPCR signaling pathways during mammalian development
Disease models: prostate, breast and non-small cell lung cancers

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Greg Lemke

Professor
Molecular Neurobiology Laboratory
Françoise Gilot-Salk Chair

Areas of interest: TAM receptor tyrosine kinase signaling in the immune system
Disease models: myeloid leukemia, metastatic lung cancer, renal cell carcinoma, prostatic carcinoma, breast cancer, and gastric cancer

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Björn Lillemeier

Associate Professor
Waitt Advanced Biophotonics Center

Areas of interest: T cell receptor signaling mechanisms
Disease models: with immune cell cancers, including chronic lymphocytic leukemia

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Vicki Lundblad

Professor
Molecular and Cell Biology Laboratory
Becky and Ralph S. O'Connor Chair

Areas of interest: telomeres and telomerase regulation in yeast
Disease models: therapeutic targets for telomerase inhibition in cancer

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Dmitry Lyumkis

Assistant Professor
Laboratory of Genetics

Areas of interest: decoding structures of macromolecular assembly using CryoEMDisease models: cancer, inflammation
Disease models: cancer, inflammation

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Graham McVicker

Assistant Professor
Laboratory of Genetics

Areas of interest: human genetic variation impacting immune system and cancer
Disease models: leukemias, pediatric blood cancers

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Marc Montminy

Professor
Clayton Foundation Laboratories for Peptide Biology
J.W. Kieckhefer Foundation Chair

Areas of interest: CRTC family transcriptional coactivators and glucose homeostasis
Disease models: insulin signaling and cancer, diabetes

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Axel Nimmerjahn

Associate Professor
Waitt Advanced Biophotonics Center

Areas of interest: imaging tools to study glial cell dynamics in the live brain, and in glioblastomas
Disease models: glioblastoma

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Joseph Noel

Professor and Director
Jack H. Skirball Center for Chemical Biology and Proteomics
Howard Hughes Medical Institute Investigator
Arthur and Julie Woodrow Chair

Areas of interest: biosynthetic enzyme engineering
Disease models: anti-cancer agents

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Clodagh O’Shea

Professor
Molecular and Cell Biology Laboratory
Howard Hughes Medical Institute Faculty Scholar

Areas of interest: oncolytic adenoviruses, adenovirus genome engineering and E4-ORF3 function
Disease models: tumor-selective oncolytic viral therapy

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Satchidananda Panda

Professor
Regulatory Biology Laboratory

Areas of interest: circadian rhythms and metabolism
Disease models: colon, endometrial, breast and liver cancer

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Samuel Pfaff

Professor
Gene Expression Laboratory
Howard Hughes Medical Institute Investigator
Benjamin H. Lewis Chair

Areas of interest: signaling principles that control specification/connectivity of spinal neurons in locomotion
Disease models: post-polio syndrome

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Alan Saghatelian

Professor
Clayton Foundation Laboratories for Peptide Biology
Dr. Frederik Paulsen Chair

Areas of interest: signaling principles that control specification/connectivity of spinal neurons in locomotion
Disease models: Global lipid and peptide profiling of cancer (colon, lung cancer) and metabolic diseases

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Gerald Shadel

Professor
Molecular and Cell Biology Laboratory
Audrey Geisel Chair in Biomedical Science

Areas of interest: role of mitochondria in disease, aging, and immune function
Disease models: mitochondrial function in different cancers and neurodegenerative disorders

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Reuben Shaw

Professor
Molecular and Cell Biology Laboratory
William R. Brody Chair

Areas of interest: metabolic changes and vulnerabilities in cancer, starvation signaling
Disease models: lung cancer, hamartoma syndromes

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Edward Stites

Assistant Professor
Integrative Biology Laboratory

Areas of interest: computation modeling of cancer mutations, RAS pathway
Disease models: colon cancer, lung cancer, pancreatic cancer

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Geoffrey Wahl

Professor
Gene Expression Laboratory
Daniel and Martina Lewis Chair

Areas of interest: p53 regulation, normal stem cells and stem-like cells in breast cancer, tumor heterogeneity
Disease models: breast cancer

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Ye Zheng

Associate Professor
NOMIS Center for Immunobiology and Microbial Pathogenesis

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