Resources
Key Components of Salk CESCG
Ultra high throughput Sequencing Capabilities
- Whole genome bisulfite sequencing (MethylC-seq for DNA methylation profiling)
- RNA-seq (transcriptome profiling)
- Whole genome sequencing
- ATAC-seq (TFBS – transcription factor binding sites profiling)
- ChIP-seq (TFBS / histone modifications)
- Hi-C (chromatin conformation pofiling)
Expert bioinformatics analysis
- Uniform processing pipelines (mostly in sync with ENCODE standards)
- High QC standards – assay dependent
- In-house developed algorithms (eg., MethylPy) and other standard analysis software
State-of-the-art compute Infrastructure
- 10 Cisco UCS server blades (expandable)
- 240 Xeon processor cores (480 with hyper threading)
- 2.56 terabytes of memory (256GB per blade)
- 400 terabytes of disk storage (expandable)
- Tape and cloud archival of raw and processed data
We have streamlined the process of data generation, QC, analysis as outlined in the flowchart below:
