Our lab is interested in understanding the molecular genetics of metabolic disease and inflammation, including atherosclerosis and diabetes as well as cancer, and using this information to devise cures for their treatment. By tinkering with a metabolic program in muscle, we stumbled upon ‘exercise in a pill.’
Professor Clayton Foundation Laboratories for Peptide Biology J. W. Kieckhefer Foundation Chair
(858) 453-4100 x1394 email@example.com
Obesity is a major risk factor in the development of adult-onset diabetes, which is characterized by the inability of cells in the body to respond to insulin. By studying key genetic switches that control food intake and metabolism, we hope to identify molecules that will be amenable to drug therapy for insulin-resistant individuals.
Professor Molecular and Cell Biology Laboratory William R. Brody Chair
(858) 453-4100 x1258 firstname.lastname@example.org
When a normal cell runs low on energy, it won’t divide, but in some cases, cancer cells can override the built-in shutoff. The same cellular brake helps cells and organisms adapt their glucose metabolism. I am particularly interested in understanding the molecular link between cancer and metabolism since it embodies a critical intervention point for future therapeutics.