UPDATE: Additional research from the Salk Institute published September 29 in eLife further details how the two receptors are critically different, having implications for treatments for autoimmune disease.
LA JOLLA—In most of the tissues of the body, specialized immune cells are entrusted with the task of engulfing the billions of dead cells that are generated every day. When these garbage disposals don’t do their job, dead cells and their waste products rapidly pile up, destroying healthy tissue and leading to autoimmune diseases such as lupus and rheumatoid arthritis.
LA JOLLA–A synthetic derivative of vitamin D was found by Salk Institute researchers to collapse the barrier of cells shielding pancreatic tumors, making this seemingly impenetrable cancer much more susceptible to therapeutic drugs.read more >>
LA JOLLA–Scientists at the Salk Institute have discovered an on-and-off “switch” in cells that may hold the key to healthy aging. This switch points to a way to encourage healthy cells to keep dividing and generating, for example, new lung or liver tissue, even in old age.read more >>
LA JOLLA—For the first time, scientists have turned human skin cells into transplantable white blood cells, soldiers of the immune system that fight infections and invaders. The work, done at the Salk Institute, could let researchers create therapies that introduce into the body new white blood cells capable of attacking diseased or cancerous cells or augmenting immune responses against other disorders.read more >>
LA JOLLA–Charles Stevens, a professor in the Salk Institute’s Molecular Neurobiology Laboratory, will receive one of 36 Early Concept Grants for Exploratory Research (EAGER) from the National Science Foundation to further research on how complex behaviors emerge from the activity of the brain.read more >>
LA JOLLA—The Salk Institute for Biological Studies celebrates another successful year of fundraising with nearly $68 million raised in fiscal year 2014 to support The Campaign for Salk, the Institute’s first-ever capital fundraising campaign.read more >>
LA JOLLA–When faced with pathogens, the immune system summons a swarm of cells made up of soldiers and peacekeepers. The peacekeeping cells tell the soldier cells to halt fighting when invaders are cleared. Without this cease-fire signal, the soldiers, known as killer T cells, continue their frenzied attack and turn on the body, causing inflammation and autoimmune disorders such as allergies, asthma, rheumatoid arthritis, multiple sclerosis and type 1 diabetes.read more >>
LA JOLLA–Scientists at the Salk Institute for Biological Studies have identified a gene that regulates sleep and wake rhythms.read more >>
Stephen F. Heinemann, whose pioneering research on neurotransmitter receptors in the brain helped lay the groundwork for understanding diseases of the brain, died August 6 of complications of kidney failure at Vibra Hospital in San Diego, California. He was 75.read more >>
LA JOLLA–Tickets are on sale now for the Salk Institute’s 19th Annual Symphony at Salk, one of the summer’s premiere events, taking place on Saturday, August 23. The annual musical affair features the highly regarded San Diego Symphony along with Emmy, Tony and Golden Globe-nominated star Matthew Morrison.read more >>