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ON THE COVER:

A layer of regulatory information on top

of our genome—called the epigenome—

is proving to be as important as genes

for the health of our bodies and minds.

Courtesy of Scot Nicholls

02

DISCOVERIES

10

IN MEMORIAM: JOHN CODEY

28

ANALYSIS

30

IN MEMORIAM: CONRAD PREBYS

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SPOTLIGHT

35

EVENTS

38

RESOLUTION

40

WAYS OF GIVING

FRONTIERS

The importance

of epigenomics

for development,

health and sickness

12

Tapping our immune

system’s superpower

22

OBSERVATIONS

All about town

with Pablo Hollstein

26

NEXTGEN

CONTENTS