{"id":50829,"date":"2024-09-19T15:36:13","date_gmt":"2024-09-19T22:36:13","guid":{"rendered":"https:\/\/www.salk.edu\/?page_id=50829"},"modified":"2026-06-23T18:30:53","modified_gmt":"2026-06-24T01:30:53","slug":"news","status":"publish","type":"page","link":"https:\/\/www.salk.edu\/es\/neuroimmunology\/news\/","title":{"rendered":"Noticias"},"content":{"rendered":"<h2>How can scientists visualize cellular life with greater precision?<\/h2>\r\n\r\n<figure class=\"right-align\">\r\n    <img decoding=\"async\" src=\"https:\/\/www.salk.edu\/wp-content\/uploads\/2026\/04\/260422-pr-nimmerjahn-microscopy-1.jpg\" alt=\"Mouse brain tissue showing inhibitory neurons labeled with a red fluorescent VIS-Fb that binds to the green calcium biosensor. Neurons are highlighted in blue.\" width=\"300\">\r\n    <figcaption>Mouse brain tissue showing inhibitory neurons labeled with a red fluorescent VIS-Fb that binds to the green calcium biosensor. Neurons are highlighted in blue.<br \/>Credit: Barykina et al., <em>Naturaleza M\u00e9todos<\/em><\/figcaption>\r\n<\/figure>\r\n\r\n<p>LA JOLLA\u2014Fluorescent proteins have revolutionized science, enabling researchers to tag and visualize individual molecules in living cells, tissues, and animals. Using these tools, researchers have watched viruses infect cells in real time, observed cellular trash collection, and tracked the signaling that spurs tumor growth.<\/p>\r\n\r\n<p>Salk scientists and collaborators at Albert Einstein College of Medicine have advanced this visualization technology. The new technology, called visible-spectrum antigen-stabilizable fluorescent nanobodies (VIS-Fbs), was validated in multiple mammalian cell types and provides a powerful tool for a wide range of life science research applications.<\/p>\r\n\r\n<p>El estudio se public\u00f3 en <a href=\"https:\/\/www.nature.com\/articles\/s41592-026-03056-3\" target=\"_blank\"><em>Naturaleza M\u00e9todos<\/em><\/a> on April 22, 2026.<\/p>\r\n\r\n<p>\u201cThis work establishes a versatile platform for imaging proteins with high specificity and minimal background,\u201d says co-corresponding author <a href=\"https:\/\/www.salk.edu\/es\/scientist\/axel-nimmerjahn\/\">Axel Nimmerjahn, doctor<\/a>, professor and Fran\u00e7oise Gilot-Salk Chair at Salk. \u201cIt opens new opportunities to study how molecular and cellular processes unfold in real time across diverse biological systems.\u201d<\/p>\r\n\r\n<p><a href=\"https:\/\/www.salk.edu\/es\/news-release\/how-can-scientists-visualize-cellular-life-with-greater-precision\/\" class=\"btn -expand\">Keep Reading &raquo;<\/a><\/p>\r\n\r\n<hr>\r\n\r\n<h2>Beyond Lab Walls Podcast: Nicola Allen on brain inflammation and lifelong cognitive health<\/h2>\r\n\r\n<div class=\"right-align\"><div class=\"row\" style=\"\"><div class=\"col-md-12 col-md-push-0\"><div class=\"video-anchor\" id=\"video-a_q1E1aCiqU\"><\/div><div class=\"embed-responsive embed-responsive-16by9\"> <iframe class=\"embed-responsive-item\" src=\"\/\/www.youtube.com\/embed\/a_q1E1aCiqU?rel=0\" webkitallowfullscreen mozallowfullscreen allowfullscreen><\/iframe><\/div><!-- .embed-responsive --><\/div><!-- .col-md-*size --><\/div><!-- .\/row --><\/div>\r\n\r\n<p>Some of the most important work of protecting the brain may depend on immune and other cell types, which make up a surprising 50% of the human brain. In this special Beyond Lab Walls video podcast episode\u2014part of the <a href=\"https:\/\/www.salk.edu\/es\/science\/2026-the-salk-institutes-year-of-brain-health-research\/\">Salk Institute\u2019s 2026 Year of Brain Health<\/a>\u2014Salk President <a href=\"https:\/\/www.salk.edu\/es\/scientist\/gerald-joyce\/\">Dr. Gerald Joyce, m\u00e9dico y doctor en Medicina<\/a>, speaks with <a href=\"https:\/\/www.salk.edu\/es\/scientist\/nicola-allen\/\">Nicola Allen, doctora<\/a>, a leading neuroscientist whose lab studies how non-neuronal brain cells shape brain function in health, aging, and disease.<\/p>\r\n\r\n<p><a href=\"https:\/\/youtu.be\/a_q1E1aCiqU?si=oICHYakcHpRNXEte\" class=\"btn -expand\" target=\"_blank\">Watch the Podcast &raquo;<\/a><\/p>\r\n\r\n<hr>\r\n\r\n<h2>Rompiendo la barrera entre la neurociencia y la inmunolog\u00eda<\/h2>\r\n\r\n<figure class=\"right-align\">\r\n    <img decoding=\"async\" src=\"https:\/\/www.salk.edu\/wp-content\/uploads\/2025\/07\/2507-nomis-ni-news.jpg\" alt=\"From left: Nicola Allen, Diana Hargreaves, and Jesse Dixon.\" width=\"300\">\r\n    <figcaption>From top left: Susan Kaech and Nicola Allen. From bottom left: Diana Hargreaves and Axel Nimmerjahn.<br \/>Cr\u00e9dito: Instituto Salk<\/figcaption>\r\n<\/figure>\r\n\r\n<p>Given their central role in running the body, it\u2019s unsurprising that the brain and spinal cord are afforded considerable protection. For example, the tightly sealed capillary network that oxygenates and nourishes the brain also acts as a critical barrier that allows only a tiny subset of physiologically important molecules to pass through while deflecting the rest. Historically, the scientific community has believed that the immune cells circulating in our bloodstream are also barred from crossing the velvet rope into the VIP room of the central nervous system (CNS).<\/p>\r\n\r\n<p>In some cases, this prohibition is lifted, as in the case of viral or bacterial infections that specifically affect the brain and require a rapid response from the immune system. \u201cWe knew immune cells could enter the brain under those kinds of conditions,\u201d says Susan Kaech, an immunologist at the Salk Institute for Biological Studies. \u201cBut at steady-state in health, it was really considered an immune-privileged organ.\u201d<\/p>\r\n\r\n<p>Research from the past decade or so has overturned that dogma, however. Kaech credits this shift largely to pioneering work that has uncovered previously overlooked networks of lymphatic structures that allow cells from the immune system to keep careful tabs on the brain even when no infection is underway. Other recent studies have established a role for communication between the CNS and circulating immune cells in disease states ranging from chronic pain to cancer to age-related neurodegeneration and Alzheimer\u2019s.<\/p>\r\n\r\n<p><a href=\"https:\/\/www.science.org\/content\/article\/breaking-barrier-between-neuroscience-and-immunology\" class=\"btn -expand\" target=\"_blank\">Keep reading &raquo;<\/a><\/p>\r\n\r\n<hr>\r\n\r\n<h2>Salk Institute promotes three faculty members in neuroscience, immunology, and cancer research<\/h2>\r\n\r\n<figure class=\"right-align\">\r\n    <img decoding=\"async\" src=\"https:\/\/www.salk.edu\/wp-content\/uploads\/2025\/04\/250421-pr-promotions-allen-hargreaves-dixon-458x149.jpg\" alt=\"From left: Nicola Allen, Diana Hargreaves, and Jesse Dixon.\" width=\"300\">\r\n    <figcaption>From left: Nicola Allen, Diana Hargreaves, and Jesse Dixon.<br \/>Cr\u00e9dito: Instituto Salk<\/figcaption>\r\n<\/figure>\r\n\r\n<p>LA JOLLA\u2014Three Salk Institute faculty members have been promoted for their notable, innovative contributions to science. Associate Professors <a href=\"https:\/\/www.salk.edu\/es\/scientist\/nicola-allen\/\">Nicola Allen<\/a> y <a href=\"https:\/\/www.salk.edu\/es\/scientist\/diana-hargreaves\/\">Diana Hargreaves<\/a> were promoted to full professors, and Assistant Professor <a href=\"https:\/\/www.salk.edu\/es\/scientist\/jesse-dixon\/\">Jesse Dixon<\/a> was promoted to associate professor. The promotions were based on Salk faculty and nonresident fellow recommendations and approved by Salk\u2019s president and Board of Trustees on April 4, 2025.<\/p>\r\n\r\n<p>\u201cNicola, Diana, and Jesse are all pushing the boundaries of what is known and what is considered possible in their respective fields,\u201d says Salk President <a href=\"https:\/\/www.salk.edu\/es\/scientist\/gerald-joyce\/\">Gerald Joyce<\/a>. \u201cNicola has also made critical contributions to Salk\u2019s programs in neuroimmunology and Alzheimer\u2019s disease, and both Diana and Jesse have made important advances in cancer research. We are excited to see how their leadership and innovation will continue to shape the Institute\u2019s success.\u201d<\/p>\r\n\r\n<p><a href=\"https:\/\/www.salk.edu\/es\/news-release\/salk-institute-promotes-three-faculty-members-in-neuroscience-immunology-and-cancer-research\/\" class=\"btn -expand\">Keep reading &raquo;<\/a><\/p>\r\n\r\n<hr>\r\n\r\n<h2>Salk Institute launches Neuroimmunology Initiative with $20 million gift from\r\nNOMIS Foundation<\/h2>\r\n<p><strong>Scientists will explore the understudied crosstalk between the immune and nervous systems,\r\nand the role it plays in health and disease<\/strong><\/p>\r\n\r\n<figure class=\"right-align\">\r\n    <img decoding=\"async\" src=\"https:\/\/www.salk.edu\/wp-content\/uploads\/2024\/06\/NOMIS-PR-300x300.jpg\" alt=\"From top left:  Susan Kaech and Nicola Allen. From bottom left: Axel Nimmerjahn and Diana Hargreaves.\" width=\"300\">\r\n    <figcaption>From top left:  Susan Kaech and Nicola Allen. From bottom left: Axel Nimmerjahn and Diana Hargreaves.<br \/>Cr\u00e9dito: Instituto Salk<\/figcaption>\r\n<\/figure>\r\n\r\n\r\n<p>LA JOLLA\u2014The Salk Institute will receive $20 million over four years from the NOMIS\r\nFoundation to launch a new Neuroimmunology Initiative within the Institute\u2019s <a href=\"https:\/\/www.salk.edu\/es\/science\/research-centers\/nomis-center\/\">NOMIS Centerfor Immunobiology and Microbial Pathogenesis<\/a>. By funding research programs, faculty\r\nrecruitment, and pilot grants, the generous gift will enable Salk scientists to develop a deep\r\nunderstanding of the crosstalk between the immune and nervous systems and the role it plays\r\nin health and disease.<\/p><p>\r\n\u201cWe are deeply grateful to the NOMIS Foundation for investing in neuroimmunology and in\r\nSalk,\u201d says Salk President <a href=\"https:\/\/www.salk.edu\/es\/scientist\/gerald-joyce\/\">Gerald Joyce<\/a>. \u201cThis funding will allow us to tackle currently\r\nunaddressed scientific questions, opening fundamentally new areas of scientific inquiry across\r\nhuman health and disease, and paving the way toward innovative therapeutic interventions for\r\na wide range of disorders that have both a neurological and immunological component, such as\r\nAlzheimer\u2019s disease, ALS, long COVID, and some forms of cancer.\"<\/p>\r\n<p><a href=\"https:\/\/www.salk.edu\/es\/news-release\/salk-institute-launches-neuroimmunology-initiative-with-20-million-gift-from-nomis-foundation\/\" class=\"btn -expand\">Keep reading &raquo;<\/a><\/p>","protected":false},"excerpt":{"rendered":"<h2>How can scientists visualize cellular life with greater precision?<\/h2>\r\n\r\n<figure class=\"right-align\">\r\n    <img decoding=\"async\" src=\"https:\/\/www.salk.edu\/wp-content\/uploads\/2026\/04\/260422-pr-nimmerjahn-microscopy-1.jpg\" alt=\"Mouse brain tissue showing inhibitory neurons labeled with a red fluorescent VIS-Fb that binds to the green calcium biosensor. Neurons are highlighted in blue.\" width=\"300\">\r\n    <figcaption>Mouse brain tissue showing inhibitory neurons labeled with a red fluorescent VIS-Fb that binds to the green calcium biosensor. Neurons are highlighted in blue.<br \/>Credit: Barykina et al., <em>Naturaleza M\u00e9todos<\/em><\/figcaption>\r\n<\/figure>\r\n\r\n<p>LA JOLLA\u2014Fluorescent proteins have revolutionized science, enabling researchers to tag and visualize individual molecules in living cells, tissues, and animals. Using these tools, researchers have watched viruses infect cells in real time, observed cellular trash collection, and tracked the signaling that spurs tumor growth.<\/p>","protected":false},"author":3,"featured_media":0,"parent":50819,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"folder":[],"class_list":["post-50829","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>News - Salk Institute for Biological Studies<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.salk.edu\/es\/neuroimmunology\/news\/\" \/>\n<meta property=\"og:locale\" content=\"es_MX\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"News - Salk Institute for Biological Studies\" \/>\n<meta property=\"og:description\" content=\"How can scientists visualize cellular life with greater precision?        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Using these tools, researchers have watched viruses infect cells in real time, observed cellular trash collection, and tracked the signaling that spurs tumor growth.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.salk.edu\/es\/neuroimmunology\/news\/\" \/>\n<meta property=\"og:site_name\" content=\"Salk Institute for Biological Studies\" \/>\n<meta property=\"article:modified_time\" content=\"2026-06-24T01:30:53+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.salk.edu\/wp-content\/uploads\/2026\/04\/260422-pr-nimmerjahn-microscopy-1.jpg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"5 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.salk.edu\\\/neuroimmunology\\\/news\\\/\",\"url\":\"https:\\\/\\\/www.salk.edu\\\/neuroimmunology\\\/news\\\/\",\"name\":\"News - Salk Institute for Biological Studies\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.salk.edu\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.salk.edu\\\/neuroimmunology\\\/news\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.salk.edu\\\/neuroimmunology\\\/news\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.salk.edu\\\/wp-content\\\/uploads\\\/2026\\\/04\\\/260422-pr-nimmerjahn-microscopy-1.jpg\",\"datePublished\":\"2024-09-19T22:36:13+00:00\",\"dateModified\":\"2026-06-24T01:30:53+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.salk.edu\\\/neuroimmunology\\\/news\\\/#breadcrumb\"},\"inLanguage\":\"es-MX\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.salk.edu\\\/neuroimmunology\\\/news\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"es-MX\",\"@id\":\"https:\\\/\\\/www.salk.edu\\\/neuroimmunology\\\/news\\\/#primaryimage\",\"url\":\"https:\\\/\\\/www.salk.edu\\\/wp-content\\\/uploads\\\/2026\\\/04\\\/260422-pr-nimmerjahn-microscopy-1.jpg\",\"contentUrl\":\"https:\\\/\\\/www.salk.edu\\\/wp-content\\\/uploads\\\/2026\\\/04\\\/260422-pr-nimmerjahn-microscopy-1.jpg\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.salk.edu\\\/neuroimmunology\\\/news\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/www.salk.edu\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"The NOMIS Center\u2019s Neuroimmunology Initiative\",\"item\":\"https:\\\/\\\/www.salk.edu\\\/neuroimmunology\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"News\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.salk.edu\\\/#website\",\"url\":\"https:\\\/\\\/www.salk.edu\\\/\",\"name\":\"Salk Institute for Biological Studies\",\"description\":\"The Power of Science\",\"publisher\":{\"@id\":\"https:\\\/\\\/www.salk.edu\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.salk.edu\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"es-MX\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/www.salk.edu\\\/#organization\",\"name\":\"Salk Institute for Biological Studies\",\"url\":\"https:\\\/\\\/www.salk.edu\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"es-MX\",\"@id\":\"https:\\\/\\\/www.salk.edu\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"http:\\\/\\\/www.salk.edu\\\/wp-content\\\/uploads\\\/2023\\\/03\\\/salk_logo_696.jpg\",\"contentUrl\":\"http:\\\/\\\/www.salk.edu\\\/wp-content\\\/uploads\\\/2023\\\/03\\\/salk_logo_696.jpg\",\"width\":696,\"height\":696,\"caption\":\"Salk Institute for Biological Studies\"},\"image\":{\"@id\":\"https:\\\/\\\/www.salk.edu\\\/#\\\/schema\\\/logo\\\/image\\\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"News - Salk Institute for Biological Studies","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.salk.edu\/es\/neuroimmunology\/news\/","og_locale":"es_MX","og_type":"article","og_title":"News - Salk Institute for Biological Studies","og_description":"How can scientists visualize cellular life with greater precision?        Mouse brain tissue showing inhibitory neurons labeled with a red fluorescent VIS-Fb that binds to the green calcium biosensor. Neurons are highlighted in blue.Credit: Barykina et al., Nature Methods   LA JOLLA\u2014Fluorescent proteins have revolutionized science, enabling researchers to tag and visualize individual molecules in living cells, tissues, and animals. Using these tools, researchers have watched viruses infect cells in real time, observed cellular trash collection, and tracked the signaling that spurs tumor growth.","og_url":"https:\/\/www.salk.edu\/es\/neuroimmunology\/news\/","og_site_name":"Salk Institute for Biological Studies","article_modified_time":"2026-06-24T01:30:53+00:00","og_image":[{"url":"https:\/\/www.salk.edu\/wp-content\/uploads\/2026\/04\/260422-pr-nimmerjahn-microscopy-1.jpg","type":"","width":"","height":""}],"twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"5 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.salk.edu\/neuroimmunology\/news\/","url":"https:\/\/www.salk.edu\/neuroimmunology\/news\/","name":"News - Salk Institute for Biological 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Biol\u00f3gicos","url":"https:\/\/www.salk.edu\/","logo":{"@type":"ImageObject","inLanguage":"es-MX","@id":"https:\/\/www.salk.edu\/#\/schema\/logo\/image\/","url":"http:\/\/www.salk.edu\/wp-content\/uploads\/2023\/03\/salk_logo_696.jpg","contentUrl":"http:\/\/www.salk.edu\/wp-content\/uploads\/2023\/03\/salk_logo_696.jpg","width":696,"height":696,"caption":"Salk Institute for Biological Studies"},"image":{"@id":"https:\/\/www.salk.edu\/#\/schema\/logo\/image\/"}}]}},"ACF":{"hero":"https:\/\/www.salk.edu\/wp-content\/uploads\/2024\/09\/neuro-immunologyheader.jpg","line_1":"The NOMIS Center\u2019s Neuroimmunology Initiative","line_2":"News","poster_quote":"","salk_custom_body_class":"","gallery":false,"secondary_navigation":"<div class=\"menu-neuroimmunology-initiative-container\"><ul id=\"menu-neuroimmunology-initiative\" class=\"menu\"><li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-50834\"><a href=\"https:\/\/www.salk.edu\/es\/neuroimmunology\/\">Overview<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-50837\"><a href=\"https:\/\/www.salk.edu\/es\/neuroimmunology\/meet-the-scientists\/\">Meet the Scientists<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-51054\"><a href=\"https:\/\/www.salk.edu\/es\/neuroimmunology\/our-research\/\">Research<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-50908\"><a href=\"https:\/\/www.salk.edu\/es\/neuroimmunology\/publications\/\">Publications<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-50836\"><a href=\"https:\/\/www.salk.edu\/es\/neuroimmunology\/news\/\">News<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-50904\"><a href=\"https:\/\/www.salk.edu\/es\/neuroimmunology\/events\/\">Events<\/a><\/li>\n<li class=\"menu-item 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