{"id":447,"date":"2015-09-10T14:28:21","date_gmt":"2015-09-10T21:28:21","guid":{"rendered":"https:\/\/vermont.salk.edu\/?page_id=447"},"modified":"2024-01-30T14:17:13","modified_gmt":"2024-01-30T22:17:13","slug":"crick-jacobs-center","status":"publish","type":"page","link":"https:\/\/www.salk.edu\/es\/science\/research-centers\/crick-jacobs-center\/","title":{"rendered":"Crick-Jacobs Center for Theoretical and Computational Biology"},"content":{"rendered":"<p>The Crick-Jacobs Center for Theoretical and Computational Biology is an interdisciplinary research unit at the Salk Institute. The overall goal of the Center is to integrate experimental and theoretical approaches to understanding the organization of signaling systems and the functional neuroanatomy of the brain, from the molecular to the systems levels, and how behavior arises from the interactions between the brain&#8217;s many components. The scientists who work at the Crick-Jacobs Center combine approaches from biology, physics, chemistry, mathematics, computer science, and engineering and exploit techniques that include computer simulations, imaging, viral vectors, and molecular genetics.<\/p>\n<p>The Center is named in honor of Francis Crick, Salk Nobel laureate, and Irwin Jacobs, who is the co-founder and chairman of the board of San Diego-based Qualcomm Inc., an international leader in digital wireless technology.<\/p>","protected":false},"excerpt":{"rendered":"<p>The Crick-Jacobs Center for Theoretical and Computational Biology is an interdisciplinary research unit at the Salk Institute. The overall goal of the Center is to integrate experimental and theoretical approaches to understanding the organization of signaling systems and the functional neuroanatomy of the brain, from the molecular to the systems levels, and how behavior arises from the interactions between the brain&#8217;s many components. The scientists who work at the Crick-Jacobs Center combine approaches from biology, physics, chemistry, mathematics, computer science, and engineering and exploit techniques that include computer simulations, imaging, viral vectors, and molecular genetics.<\/p>","protected":false},"author":3,"featured_media":6300,"parent":76,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"template-research-centers-overview.php","meta":{"_acf_changed":false,"footnotes":""},"folder":[539],"class_list":["post-447","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Crick-Jacobs Center for Theoretical and Computational Biology - Salk Institute for Biological Studies<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.salk.edu\/es\/science\/research-centers\/crick-jacobs-center\/\" \/>\n<meta property=\"og:locale\" content=\"es_MX\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Crick-Jacobs Center for Theoretical and Computational Biology - Salk Institute for Biological Studies\" \/>\n<meta property=\"og:description\" content=\"The Crick-Jacobs Center for Theoretical and Computational Biology is an interdisciplinary research unit at the Salk Institute. The overall goal of the Center is to integrate experimental and theoretical approaches to understanding the organization of signaling systems and the functional neuroanatomy of the brain, from the molecular to the systems levels, and how behavior arises from the interactions between the brain&#8217;s many components. The scientists who work at the Crick-Jacobs Center combine approaches from biology, physics, chemistry, mathematics, computer science, and engineering and exploit techniques that include computer simulations, imaging, viral vectors, and molecular genetics.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.salk.edu\/es\/science\/research-centers\/crick-jacobs-center\/\" \/>\n<meta property=\"og:site_name\" content=\"Salk Institute for Biological Studies\" \/>\n<meta property=\"article:modified_time\" content=\"2024-01-30T22:17:13+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/11\/Francis-Crick-DNAmodel.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"767\" \/>\n\t<meta property=\"og:image:height\" content=\"767\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.salk.edu\\\/science\\\/research-centers\\\/crick-jacobs-center\\\/\",\"url\":\"https:\\\/\\\/www.salk.edu\\\/science\\\/research-centers\\\/crick-jacobs-center\\\/\",\"name\":\"Crick-Jacobs Center for Theoretical and Computational Biology - Salk Institute for Biological Studies\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.salk.edu\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.salk.edu\\\/science\\\/research-centers\\\/crick-jacobs-center\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.salk.edu\\\/science\\\/research-centers\\\/crick-jacobs-center\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.salk.edu\\\/wp-content\\\/uploads\\\/2015\\\/11\\\/Francis-Crick-DNAmodel.jpg\",\"datePublished\":\"2015-09-10T21:28:21+00:00\",\"dateModified\":\"2024-01-30T22:17:13+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.salk.edu\\\/science\\\/research-centers\\\/crick-jacobs-center\\\/#breadcrumb\"},\"inLanguage\":\"es-MX\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.salk.edu\\\/science\\\/research-centers\\\/crick-jacobs-center\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"es-MX\",\"@id\":\"https:\\\/\\\/www.salk.edu\\\/science\\\/research-centers\\\/crick-jacobs-center\\\/#primaryimage\",\"url\":\"https:\\\/\\\/www.salk.edu\\\/wp-content\\\/uploads\\\/2015\\\/11\\\/Francis-Crick-DNAmodel.jpg\",\"contentUrl\":\"https:\\\/\\\/www.salk.edu\\\/wp-content\\\/uploads\\\/2015\\\/11\\\/Francis-Crick-DNAmodel.jpg\",\"width\":767,\"height\":767,\"caption\":\"Francis Crick (1916-2004)\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.salk.edu\\\/science\\\/research-centers\\\/crick-jacobs-center\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/www.salk.edu\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Science\",\"item\":\"https:\\\/\\\/www.salk.edu\\\/science\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Research Centers\",\"item\":\"https:\\\/\\\/www.salk.edu\\\/science\\\/research-centers\\\/\"},{\"@type\":\"ListItem\",\"position\":4,\"name\":\"Crick-Jacobs Center for Theoretical and Computational Biology\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.salk.edu\\\/#website\",\"url\":\"https:\\\/\\\/www.salk.edu\\\/\",\"name\":\"Salk Institute for Biological Studies\",\"description\":\"The Power of Science\",\"publisher\":{\"@id\":\"https:\\\/\\\/www.salk.edu\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.salk.edu\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"es-MX\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/www.salk.edu\\\/#organization\",\"name\":\"Salk Institute for Biological Studies\",\"url\":\"https:\\\/\\\/www.salk.edu\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"es-MX\",\"@id\":\"https:\\\/\\\/www.salk.edu\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"http:\\\/\\\/www.salk.edu\\\/wp-content\\\/uploads\\\/2023\\\/03\\\/salk_logo_696.jpg\",\"contentUrl\":\"http:\\\/\\\/www.salk.edu\\\/wp-content\\\/uploads\\\/2023\\\/03\\\/salk_logo_696.jpg\",\"width\":696,\"height\":696,\"caption\":\"Salk Institute for Biological Studies\"},\"image\":{\"@id\":\"https:\\\/\\\/www.salk.edu\\\/#\\\/schema\\\/logo\\\/image\\\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Crick-Jacobs Center for Theoretical and Computational Biology - Salk Institute for Biological Studies","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.salk.edu\/es\/science\/research-centers\/crick-jacobs-center\/","og_locale":"es_MX","og_type":"article","og_title":"Crick-Jacobs Center for Theoretical and Computational Biology - Salk Institute for Biological Studies","og_description":"The Crick-Jacobs Center for Theoretical and Computational Biology is an interdisciplinary research unit at the Salk Institute. The overall goal of the Center is to integrate experimental and theoretical approaches to understanding the organization of signaling systems and the functional neuroanatomy of the brain, from the molecular to the systems levels, and how behavior arises from the interactions between the brain&#8217;s many components. The scientists who work at the Crick-Jacobs Center combine approaches from biology, physics, chemistry, mathematics, computer science, and engineering and exploit techniques that include computer simulations, imaging, viral vectors, and molecular genetics.","og_url":"https:\/\/www.salk.edu\/es\/science\/research-centers\/crick-jacobs-center\/","og_site_name":"Salk Institute for Biological Studies","article_modified_time":"2024-01-30T22:17:13+00:00","og_image":[{"width":767,"height":767,"url":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/11\/Francis-Crick-DNAmodel.jpg","type":"image\/jpeg"}],"twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.salk.edu\/science\/research-centers\/crick-jacobs-center\/","url":"https:\/\/www.salk.edu\/science\/research-centers\/crick-jacobs-center\/","name":"Crick-Jacobs Center for Theoretical and Computational Biology - Salk Institute for Biological Studies","isPartOf":{"@id":"https:\/\/www.salk.edu\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.salk.edu\/science\/research-centers\/crick-jacobs-center\/#primaryimage"},"image":{"@id":"https:\/\/www.salk.edu\/science\/research-centers\/crick-jacobs-center\/#primaryimage"},"thumbnailUrl":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/11\/Francis-Crick-DNAmodel.jpg","datePublished":"2015-09-10T21:28:21+00:00","dateModified":"2024-01-30T22:17:13+00:00","breadcrumb":{"@id":"https:\/\/www.salk.edu\/science\/research-centers\/crick-jacobs-center\/#breadcrumb"},"inLanguage":"es-MX","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.salk.edu\/science\/research-centers\/crick-jacobs-center\/"]}]},{"@type":"ImageObject","inLanguage":"es-MX","@id":"https:\/\/www.salk.edu\/science\/research-centers\/crick-jacobs-center\/#primaryimage","url":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/11\/Francis-Crick-DNAmodel.jpg","contentUrl":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/11\/Francis-Crick-DNAmodel.jpg","width":767,"height":767,"caption":"Francis Crick (1916-2004)"},{"@type":"BreadcrumbList","@id":"https:\/\/www.salk.edu\/science\/research-centers\/crick-jacobs-center\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.salk.edu\/"},{"@type":"ListItem","position":2,"name":"Science","item":"https:\/\/www.salk.edu\/science\/"},{"@type":"ListItem","position":3,"name":"Research Centers","item":"https:\/\/www.salk.edu\/science\/research-centers\/"},{"@type":"ListItem","position":4,"name":"Crick-Jacobs Center for Theoretical and Computational Biology"}]},{"@type":"WebSite","@id":"https:\/\/www.salk.edu\/#website","url":"https:\/\/www.salk.edu\/","name":"Instituto Salk de Estudios Biol\u00f3gicos","description":"The Power of Science","publisher":{"@id":"https:\/\/www.salk.edu\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.salk.edu\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"es-MX"},{"@type":"Organization","@id":"https:\/\/www.salk.edu\/#organization","name":"Instituto Salk de Estudios Biol\u00f3gicos","url":"https:\/\/www.salk.edu\/","logo":{"@type":"ImageObject","inLanguage":"es-MX","@id":"https:\/\/www.salk.edu\/#\/schema\/logo\/image\/","url":"http:\/\/www.salk.edu\/wp-content\/uploads\/2023\/03\/salk_logo_696.jpg","contentUrl":"http:\/\/www.salk.edu\/wp-content\/uploads\/2023\/03\/salk_logo_696.jpg","width":696,"height":696,"caption":"Salk Institute for Biological Studies"},"image":{"@id":"https:\/\/www.salk.edu\/#\/schema\/logo\/image\/"}}]}},"ACF":{"hero":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/11\/03E08570sm.jpg","line_1":"Crick-Jacobs Center","line_2":"Overview","secondary_navigation":"<div class=\"menu-crick-jacobs-center-container\"><ul id=\"menu-crick-jacobs-center\" class=\"menu\"><li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-472\"><a href=\"https:\/\/www.salk.edu\/es\/science\/research-centers\/crick-jacobs-center\/\">Overview<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-471\"><a href=\"https:\/\/www.salk.edu\/es\/science\/research-centers\/crick-jacobs-center\/crick-jacobs-people\/\">People<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-7360\"><a href=\"https:\/\/www.salk.edu\/es\/science\/research-centers\/crick-jacobs-center\/news-events\/\">News &#038; Events<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-7359\"><a href=\"https:\/\/www.salk.edu\/es\/science\/research-centers\/crick-jacobs-center\/contact\/\">Contact<\/a><\/li>\n<\/ul><\/div>","disease_research":[{"title":"Maximally Informative Neurons","description":"<p>Tatyana Sharpee is an assistant professor at the Crick-Jacobs Center for Theoretical and Computational Biology. She received her PhD in theoretical physics from Michigan State University in 2001, and completed her postdoctoral training in computational and theoretical neuroscience at the University of California, San Francisco. Tatyana uses methods from statistical physics and information theory to study how the brain encodes sensory stimuli. <\/p>","image":{"ID":464,"id":464,"title":"Salk-Neuronal-Gene-thumbnail","filename":"Salk-Neuronal-Gene-thumbnail.jpg","filesize":223600,"url":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-Neuronal-Gene-thumbnail.jpg","link":"https:\/\/www.salk.edu\/es\/?attachment_id=464","alt":"Joseph Ecker Science","author":"3","description":"","caption":"","name":"salk-neuronal-gene-thumbnail","status":"inherit","uploaded_to":460,"date":"2015-09-11 01:09:26","modified":"2015-10-10 00:56:28","menu_order":0,"mime_type":"image\/jpeg","type":"image","subtype":"jpeg","icon":"https:\/\/www.salk.edu\/wp-includes\/images\/media\/default.png","width":767,"height":767,"sizes":{"thumbnail":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-Neuronal-Gene-thumbnail-150x150.jpg","thumbnail-width":150,"thumbnail-height":150,"medium":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-Neuronal-Gene-thumbnail-300x300.jpg","medium-width":300,"medium-height":300,"medium_large":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-Neuronal-Gene-thumbnail.jpg","medium_large-width":767,"medium_large-height":767,"large":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-Neuronal-Gene-thumbnail.jpg","large-width":767,"large-height":767,"1536x1536":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-Neuronal-Gene-thumbnail.jpg","1536x1536-width":767,"1536x1536-height":767,"2048x2048":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-Neuronal-Gene-thumbnail.jpg","2048x2048-width":767,"2048x2048-height":767,"trp-custom-language-flag":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-Neuronal-Gene-thumbnail.jpg","trp-custom-language-flag-width":12,"trp-custom-language-flag-height":12,"hero":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-Neuronal-Gene-thumbnail-767x550.jpg","hero-width":767,"hero-height":550,"square":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-Neuronal-Gene-thumbnail.jpg","square-width":767,"square-height":767,"cision-147":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-Neuronal-Gene-thumbnail.jpg","cision-147-width":147,"cision-147-height":147,"pr-300":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-Neuronal-Gene-thumbnail.jpg","pr-300-width":300,"pr-300-height":300,"col-md-5":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-Neuronal-Gene-thumbnail-458x458.jpg","col-md-5-width":458,"col-md-5-height":458,"col-md-6":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-Neuronal-Gene-thumbnail-585x585.jpg","col-md-6-width":585,"col-md-6-height":585,"col-md-7":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-Neuronal-Gene-thumbnail-553x553.jpg","col-md-7-width":553,"col-md-7-height":553,"col-md-8":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-Neuronal-Gene-thumbnail-750x750.jpg","col-md-8-width":750,"col-md-8-height":750,"grid-767":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-Neuronal-Gene-thumbnail.jpg","grid-767-width":767,"grid-767-height":767,"col-md-10":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-Neuronal-Gene-thumbnail.jpg","col-md-10-width":767,"col-md-10-height":767,"gform-image-choice-sm":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-Neuronal-Gene-thumbnail.jpg","gform-image-choice-sm-width":300,"gform-image-choice-sm-height":300,"gform-image-choice-md":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-Neuronal-Gene-thumbnail.jpg","gform-image-choice-md-width":400,"gform-image-choice-md-height":400,"gform-image-choice-lg":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-Neuronal-Gene-thumbnail.jpg","gform-image-choice-lg-width":600,"gform-image-choice-lg-height":600}}},{"title":"Computations by Neural Circuits","description":"<p>The goal of this work is to identify the nature of computations carried out by specific parts of the brain. The approach is to combine theory and constraints provided by the structure and function of neural circuits to describe the mathematical operations performed by structures such as the primary visual cortex. The theories that result always make specific predictions that can be tested by comparison with experimental observations.<\/p>","image":{"ID":467,"id":467,"title":"Salk-MCell-thumbnail","filename":"Salk-MCell-thumbnail.jpg","filesize":159553,"url":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-MCell-thumbnail.jpg","link":"https:\/\/www.salk.edu\/es\/?attachment_id=467","alt":"","author":"3","description":"","caption":"","name":"salk-mcell-thumbnail","status":"inherit","uploaded_to":457,"date":"2015-09-11 01:10:26","modified":"2015-09-11 01:10:26","menu_order":0,"mime_type":"image\/jpeg","type":"image","subtype":"jpeg","icon":"https:\/\/www.salk.edu\/wp-includes\/images\/media\/default.png","width":767,"height":767,"sizes":{"thumbnail":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-MCell-thumbnail-150x150.jpg","thumbnail-width":150,"thumbnail-height":150,"medium":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-MCell-thumbnail-300x300.jpg","medium-width":300,"medium-height":300,"medium_large":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-MCell-thumbnail.jpg","medium_large-width":767,"medium_large-height":767,"large":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-MCell-thumbnail.jpg","large-width":767,"large-height":767,"1536x1536":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-MCell-thumbnail.jpg","1536x1536-width":767,"1536x1536-height":767,"2048x2048":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-MCell-thumbnail.jpg","2048x2048-width":767,"2048x2048-height":767,"trp-custom-language-flag":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-MCell-thumbnail.jpg","trp-custom-language-flag-width":12,"trp-custom-language-flag-height":12,"hero":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-MCell-thumbnail-767x550.jpg","hero-width":767,"hero-height":550,"square":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-MCell-thumbnail.jpg","square-width":767,"square-height":767,"cision-147":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-MCell-thumbnail.jpg","cision-147-width":147,"cision-147-height":147,"pr-300":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-MCell-thumbnail.jpg","pr-300-width":300,"pr-300-height":300,"col-md-5":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-MCell-thumbnail-458x458.jpg","col-md-5-width":458,"col-md-5-height":458,"col-md-6":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-MCell-thumbnail-585x585.jpg","col-md-6-width":585,"col-md-6-height":585,"col-md-7":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-MCell-thumbnail-553x553.jpg","col-md-7-width":553,"col-md-7-height":553,"col-md-8":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-MCell-thumbnail-750x750.jpg","col-md-8-width":750,"col-md-8-height":750,"grid-767":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-MCell-thumbnail.jpg","grid-767-width":767,"grid-767-height":767,"col-md-10":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-MCell-thumbnail.jpg","col-md-10-width":767,"col-md-10-height":767,"gform-image-choice-sm":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-MCell-thumbnail.jpg","gform-image-choice-sm-width":300,"gform-image-choice-sm-height":300,"gform-image-choice-md":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-MCell-thumbnail.jpg","gform-image-choice-md-width":400,"gform-image-choice-md-height":400,"gform-image-choice-lg":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-MCell-thumbnail.jpg","gform-image-choice-lg-width":600,"gform-image-choice-lg-height":600}}},{"title":"MCell","description":"<p>Molecular processes within cells occur in highly organized subcellular spaces, where ligand and effector molecules participate in complex signaling pathways. At this level of resolution, one cannot consider molecular signals to be well-mixed, but instead attention must center on subcellular microdomains, which include both intra- and extracellular regions such as cell and organelle membranes, which are complex barriers to ligand diffusion.<\/p>","image":{"ID":466,"id":466,"title":"Salk-CellMap-thumbnail","filename":"Salk-CellMap-thumbnail.jpg","filesize":270608,"url":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-CellMap-thumbnail.jpg","link":"https:\/\/www.salk.edu\/es\/?attachment_id=466","alt":"","author":"3","description":"","caption":"","name":"salk-cellmap-thumbnail","status":"inherit","uploaded_to":458,"date":"2015-09-11 01:10:15","modified":"2015-09-11 01:10:15","menu_order":0,"mime_type":"image\/jpeg","type":"image","subtype":"jpeg","icon":"https:\/\/www.salk.edu\/wp-includes\/images\/media\/default.png","width":767,"height":767,"sizes":{"thumbnail":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-CellMap-thumbnail-150x150.jpg","thumbnail-width":150,"thumbnail-height":150,"medium":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-CellMap-thumbnail-300x300.jpg","medium-width":300,"medium-height":300,"medium_large":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-CellMap-thumbnail.jpg","medium_large-width":767,"medium_large-height":767,"large":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-CellMap-thumbnail.jpg","large-width":767,"large-height":767,"1536x1536":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-CellMap-thumbnail.jpg","1536x1536-width":767,"1536x1536-height":767,"2048x2048":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-CellMap-thumbnail.jpg","2048x2048-width":767,"2048x2048-height":767,"trp-custom-language-flag":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-CellMap-thumbnail.jpg","trp-custom-language-flag-width":12,"trp-custom-language-flag-height":12,"hero":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-CellMap-thumbnail-767x550.jpg","hero-width":767,"hero-height":550,"square":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-CellMap-thumbnail.jpg","square-width":767,"square-height":767,"cision-147":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-CellMap-thumbnail.jpg","cision-147-width":147,"cision-147-height":147,"pr-300":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-CellMap-thumbnail.jpg","pr-300-width":300,"pr-300-height":300,"col-md-5":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-CellMap-thumbnail-458x458.jpg","col-md-5-width":458,"col-md-5-height":458,"col-md-6":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-CellMap-thumbnail-585x585.jpg","col-md-6-width":585,"col-md-6-height":585,"col-md-7":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-CellMap-thumbnail-553x553.jpg","col-md-7-width":553,"col-md-7-height":553,"col-md-8":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-CellMap-thumbnail-750x750.jpg","col-md-8-width":750,"col-md-8-height":750,"grid-767":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-CellMap-thumbnail.jpg","grid-767-width":767,"grid-767-height":767,"col-md-10":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-CellMap-thumbnail.jpg","col-md-10-width":767,"col-md-10-height":767,"gform-image-choice-sm":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-CellMap-thumbnail.jpg","gform-image-choice-sm-width":300,"gform-image-choice-sm-height":300,"gform-image-choice-md":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-CellMap-thumbnail.jpg","gform-image-choice-md-width":400,"gform-image-choice-md-height":400,"gform-image-choice-lg":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-CellMap-thumbnail.jpg","gform-image-choice-lg-width":600,"gform-image-choice-lg-height":600}}},{"title":"Neuronal Gene Regulation","description":"<p>The overall goal of this research is to study the systems and networks regulated by transcriptional complexes in neuronal differentiation and stem cell maintenance, which includes the downstream alternative splicing and microRNA networks. Nervous system development depends crucially on signaling events that lead to the maintenance of a stem cell and progenitor state, and differentiation from the stem cell or progenitor state to a neuronal or glial lineage.<\/p>","image":{"ID":468,"id":468,"title":"Salk-Computations-thumbnail","filename":"Salk-Computations-thumbnail.jpg","filesize":107612,"url":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-Computations-thumbnail.jpg","link":"https:\/\/www.salk.edu\/es\/?attachment_id=468","alt":"","author":"3","description":"","caption":"","name":"salk-computations-thumbnail","status":"inherit","uploaded_to":456,"date":"2015-09-11 01:10:39","modified":"2015-09-11 01:10:39","menu_order":0,"mime_type":"image\/jpeg","type":"image","subtype":"jpeg","icon":"https:\/\/www.salk.edu\/wp-includes\/images\/media\/default.png","width":767,"height":767,"sizes":{"thumbnail":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-Computations-thumbnail-150x150.jpg","thumbnail-width":150,"thumbnail-height":150,"medium":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-Computations-thumbnail-300x300.jpg","medium-width":300,"medium-height":300,"medium_large":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-Computations-thumbnail.jpg","medium_large-width":767,"medium_large-height":767,"large":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-Computations-thumbnail.jpg","large-width":767,"large-height":767,"1536x1536":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-Computations-thumbnail.jpg","1536x1536-width":767,"1536x1536-height":767,"2048x2048":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-Computations-thumbnail.jpg","2048x2048-width":767,"2048x2048-height":767,"trp-custom-language-flag":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-Computations-thumbnail.jpg","trp-custom-language-flag-width":12,"trp-custom-language-flag-height":12,"hero":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-Computations-thumbnail-767x550.jpg","hero-width":767,"hero-height":550,"square":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-Computations-thumbnail.jpg","square-width":767,"square-height":767,"cision-147":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-Computations-thumbnail.jpg","cision-147-width":147,"cision-147-height":147,"pr-300":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-Computations-thumbnail.jpg","pr-300-width":300,"pr-300-height":300,"col-md-5":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-Computations-thumbnail-458x458.jpg","col-md-5-width":458,"col-md-5-height":458,"col-md-6":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-Computations-thumbnail-585x585.jpg","col-md-6-width":585,"col-md-6-height":585,"col-md-7":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-Computations-thumbnail-553x553.jpg","col-md-7-width":553,"col-md-7-height":553,"col-md-8":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-Computations-thumbnail-750x750.jpg","col-md-8-width":750,"col-md-8-height":750,"grid-767":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-Computations-thumbnail.jpg","grid-767-width":767,"grid-767-height":767,"col-md-10":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-Computations-thumbnail.jpg","col-md-10-width":767,"col-md-10-height":767,"gform-image-choice-sm":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-Computations-thumbnail.jpg","gform-image-choice-sm-width":300,"gform-image-choice-sm-height":300,"gform-image-choice-md":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-Computations-thumbnail.jpg","gform-image-choice-md-width":400,"gform-image-choice-md-height":400,"gform-image-choice-lg":"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/09\/Salk-Computations-thumbnail.jpg","gform-image-choice-lg-width":600,"gform-image-choice-lg-height":600}}}],"gallery":false,"salk_custom_body_class":"","poster_quote":"","featured_image_link":""},"_links":{"self":[{"href":"https:\/\/www.salk.edu\/es\/wp-json\/wp\/v2\/pages\/447","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.salk.edu\/es\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.salk.edu\/es\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.salk.edu\/es\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.salk.edu\/es\/wp-json\/wp\/v2\/comments?post=447"}],"version-history":[{"count":43,"href":"https:\/\/www.salk.edu\/es\/wp-json\/wp\/v2\/pages\/447\/revisions"}],"predecessor-version":[{"id":42089,"href":"https:\/\/www.salk.edu\/es\/wp-json\/wp\/v2\/pages\/447\/revisions\/42089"}],"up":[{"embeddable":true,"href":"https:\/\/www.salk.edu\/es\/wp-json\/wp\/v2\/pages\/76"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.salk.edu\/es\/wp-json\/wp\/v2\/media\/6300"}],"wp:attachment":[{"href":"https:\/\/www.salk.edu\/es\/wp-json\/wp\/v2\/media?parent=447"}],"wp:term":[{"taxonomy":"folder","embeddable":true,"href":"https:\/\/www.salk.edu\/es\/wp-json\/wp\/v2\/folder?post=447"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}