{"id":50444,"date":"2024-08-19T07:02:24","date_gmt":"2024-08-19T14:02:24","guid":{"rendered":"https:\/\/www.salk.edu\/?post_type=disclosure&#038;p=50444"},"modified":"2024-08-19T13:41:41","modified_gmt":"2024-08-19T20:41:41","slug":"salk-professor-rusty-gage-awarded-2024-taylor-international-prize-in-medicine","status":"publish","type":"disclosure","link":"https:\/\/www.salk.edu\/es\/news-release\/salk-professor-rusty-gage-awarded-2024-taylor-international-prize-in-medicine\/","title":{"rendered":"Salk Professor Rusty Gage awarded 2024 Taylor International Prize in Medicine"},"content":{"rendered":"<p>LA JOLLA\u2014Professor <a href=\"https:\/\/www.salk.edu\/es\/scientist\/rusty-gage\/\">Rusty Gage<\/a> has been awarded the <a href=\"https:\/\/www.robarts.ca\/taylor_prize\/index.html\">2024 J. Allyn Taylor International Prize in Medicine<\/a> by the Schulich School of Medicine & Dentistry and the Robarts Research Institute at Western University. One of the most prestigious medical research awards in Canada, the Taylor Prize recognizes scientists for transformative, career-defining work in basic sciences, translational research, and medical innovations. \r\n<\/p>\r\n<figure id=\"attachment_36935\"  class=\"wp-caption alignright\"><img decoding=\"async\" class=\"img-responsive wp-image-36935 size-medium\" src=\"https:\/\/www.salk.edu\/wp-content\/uploads\/2024\/08\/Rusty_Gage_0X8C2882-cropped-300x394.jpg\" alt=\"Rusty Gage\" \/><figcaption class=\"wp-caption-text\">Rusty Gage<br \/><a href=\"https:\/\/www.salk.edu\/wp-content\/uploads\/2024\/08\/Rusty_Gage_0X8C2882-cropped.jpg\">Haga clic aqu\u00ed<\/a> para obtener una imagen en alta resoluci\u00f3n.<br \/>Cr\u00e9dito: Instituto Salk<\/figcaption><\/figure>\r\n\r\n<p>\r\nThis year\u2019s prize specifically honors a research leader in aging-related medical science and research\u2014a long-term focus of Gage and his lab. Gage will receive $50,000 and be celebrated at a Robarts Research Institute event in November.\r\n<\/p><p>\r\n\u201cRusty\u2019s groundbreaking efforts to develop sophisticated models of the aging brain continue to enrich our understanding of human health and disease,\u201d says Salk President <a href=\"https:\/\/www.salk.edu\/es\/scientist\/gerald-joyce\/\">Gerald Joyce<\/a>. \u201cThis prize is a testament to his ingenuity and leadership in the field of neuroscience.\u201d\r\n<\/p><p>\r\nGage is a professor in the Laboratory of Genetics, Vi and John Adler Chair for Research on Age-Related Neurodegenerative Disease, and former president of the Salk Institute. \r\n<\/p><p>\r\nGage studies how genes and environmental factors guide the plasticity, adaptability, and diversity of the human brain. To do this, he develops laboratory models of the human brain by reprogramming patients\u2019 skin cells into induced pluripotent stem cells, induced neurons, and organoids (3D collections of cells that mimic human tissues). These cutting-edge models have expanded what\u2019s possible in neuroscience research and allowed Gage to make many exciting discoveries about the brain and age-related diseases like Alzheimer\u2019s and Parkinson\u2019s. \r\n<\/p><p>\r\nIn 2015, Gage\u2019s lab pioneered <a href=\"https:\/\/www.salk.edu\/es\/news-release\/researchers-learn-how-to-grow-old-brain-cells\/\">a method to convert older people\u2019s skin cells into brain cells<\/a>, all while retaining the cells\u2019 molecular signatures of aging. In 2022, the lab used this method to discover that <a href=\"https:\/\/www.salk.edu\/es\/news-release\/deteriorating-neurons-are-source-of-human-brain-inflammation-in-alzheimers-disease\/\">deteriorating neurons can be a source of brain inflammation in Alzheimer\u2019s disease<\/a>. In two subsequent studies, Gage\u2019s lab introduced non-neuronal cells called <a href=\"https:\/\/www.salk.edu\/es\/news-release\/new-way-to-model-human-brain-immune-cells\/\">microglia<\/a> y <a href=\"https:\/\/www.salk.edu\/es\/news-release\/more-than-just-neurons-a-new-model-for-studying-human-brain-inflammation\/\">astrocytes<\/a> to their brain organoids\u2014a huge step for making organoid models more accurate representations of the human brain. \r\n<\/p><p>\r\nAs a scientific leader, Gage models the importance of collaboration through his work with Salk colleagues and global collaborators. Alongside Professor <a href=\"https:\/\/www.salk.edu\/es\/scientist\/jan-karlseder\/\">Jan Karlseder<\/a>, Gage helped create another type of tool to help scientists study aging called Telo-seq. The tool was designed to <a href=\"https:\/\/www.salk.edu\/es\/news-release\/unveiling-telo-seq-a-breakthrough-in-telomere-research-on-aging-and-cancer\/\">revolutionize the study of telomeres<\/a>\u2014the protective endcaps of our chromosomes that shrink as we age. In a new collaboration with Assistant Professor <a href=\"https:\/\/www.salk.edu\/es\/scientist\/pallav-kosuri\/\">Pallav Kosuri<\/a> funded by the W. M. Keck Foundation, he plans to investigate the way <a href=\"https:\/\/www.salk.edu\/es\/news-release\/salk-researchers-earn-1-3-million-w-m-keck-foundation-award-to-study-aging-brain\/\">brain and heart cell functions decline over time due to ribosubstitution events<\/a>, in which damaged DNA is repaired with pieces of RNA. Gage is also set to lead a new <a href=\"https:\/\/www.salk.edu\/es\/news-release\/salk-awarded-3-6-million-by-the-california-institute-for-regenerative-medicine-to-advance-research-on-brain-aging\/\">California Institute for Regenerative Medicine (CIRM) funded Shared Resources Laboratory<\/a> focused on stem cell-based models of aging and neurodegeneration. \r\n<\/p><p>\r\nGage has earned numerous awards and accolades in his career, including an International Society for Stem Cell Research Achievement Award in 2020 and ARCS Foundation Scientist of the Year in 2018. He has also remained on <a href=\"https:\/\/www.salk.edu\/es\/news-release\/seven-salk-scientists-named-among-best-and-most-highly-cited-researchers-in-the-world\/\">Clarivate\u2019s Highly Cited Researchers list<\/a> for nine years running. Additionally, he is a member of the US National Academy of Medicine, US National Academy of Sciences, American Academy of Arts and Sciences, and American Philosophical Society.\r\n<\/p><p>\r\n<strong>About the Schulich School of Medicine & Dentistry:<\/strong><br \/>\r\nWestern University\u2019s Schulich School of Medicine & Dentistry is one of Canada\u2019s preeminent medical and dental schools. Established in 1881, it was one of the founding schools of Western University. For more than 130 years, the School has demonstrated a commitment to academic excellence and a passion for scientific discovery.\r\n<\/p><p>\r\n<strong>About the Robarts Research Institute:<\/strong><br \/>\r\nOpened in 1986, Robarts Research Institute at Western University is a medical research facility in London, Ontario, with more than 600 people working to investigate some of the most debilitating diseases of our time, from heart disease and stroke to diabetes, Alzheimer\u2019s, and many forms of cancer.\r\n<\/p><p>\r\n<strong>Acerca del Instituto Salk de Estudios Biol\u00f3gicos:<\/strong><br \/>\r\nUnlocking the secrets of life itself is the driving force behind the Salk Institute. Our team of world-class, award-winning scientists pushes the boundaries of knowledge in areas such as neuroscience, cancer research, aging, immunobiology, plant biology, computational biology, and more. Founded by Jonas Salk, developer of the first safe and effective polio vaccine, the Institute is an independent, nonprofit research organization and architectural landmark: small by choice, intimate by nature, and fearless in the face of any challenge. Learn more at www.salk.edu.\r\n<\/p>","protected":false},"featured_media":50507,"template":"","faculty":[76],"disease-research":[279],"class_list":["post-50444","disclosure","type-disclosure","status-publish","has-post-thumbnail","hentry","faculty-rusty-gage","disease-research-awards"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Salk Professor Rusty Gage awarded 2024 Taylor International Prize in Medicine - Salk Institute for Biological Studies<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.salk.edu\/es\/news-release\/salk-professor-rusty-gage-awarded-2024-taylor-international-prize-in-medicine\/\" \/>\n<meta property=\"og:locale\" content=\"es_MX\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Salk Professor Rusty Gage awarded 2024 Taylor International Prize in Medicine - Salk Institute for Biological Studies\" \/>\n<meta property=\"og:description\" content=\"LA JOLLA\u2014Professor Rusty Gage has been awarded the 2024 J. 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