{"id":31560,"date":"2021-08-25T00:00:47","date_gmt":"2021-08-25T07:00:47","guid":{"rendered":"https:\/\/vermont.salk.edu\/?post_type=disclosure&p=31560"},"modified":"2023-12-10T00:10:26","modified_gmt":"2023-12-10T08:10:26","slug":"axel-nimmerjahn-leads-research-team-awarded-11-million-by-the-u19-team-research-brain-circuit-program","status":"publish","type":"disclosure","link":"https:\/\/www.salk.edu\/es\/news-release\/axel-nimmerjahn-leads-research-team-awarded-11-million-by-the-u19-team-research-brain-circuit-program\/","title":{"rendered":"Axel Nimmerjahn lidera equipo de investigaci\u00f3n galardonado con $11 millones por el Programa BRAIN Circuit de Investigaci\u00f3n de Equipos U19"},"content":{"rendered":"

LA JOLLA\u2014Profesor Asociado del Salk Axel Nimmerjahn<\/a> lidera un equipo de investigaci\u00f3n que ha recibido $11.2 millones de $ La Iniciativa de Investigaci\u00f3n Cerebral a trav\u00e9s del Avance de Neurotecnolog\u00edas Innovadoras (BRAIN)<\/a>, un esfuerzo que tiene como objetivo investigar los principios generales de la funci\u00f3n de los circuitos cerebrales, incluyendo la sensaci\u00f3n, la percepci\u00f3n, la toma de decisiones y el control motor. Nimmerjahn liderar\u00e1 un proyecto interdisciplinario de cinco a\u00f1os que investigar\u00e1 c\u00f3mo los astrocitos, c\u00e9lulas con forma de estrella en el cerebro, procesan y modulan las se\u00f1ales de las neuronas para comprender mejor la funci\u00f3n cerebral general.<\/p>\n

\"Axel
Axel Nimmerjahn
Haga clic aqu\u00ed<\/a> para obtener una imagen en alta resoluci\u00f3n.
Cr\u00e9dito: Instituto Salk<\/figcaption><\/figure>\n

\u201cEn el cerebro, alrededor de la mitad de las c\u00e9lulas no son neuronas. Tradicionalmente no se ha pensado que las c\u00e9lulas no neuronales desempe\u00f1an un papel importante en el procesamiento de informaci\u00f3n, pero esta idea est\u00e1 empezando a desmoronarse\u201d, dice Nimmerjahn, director del Salk's Centro de Biofot\u00f3nica<\/a>. Piensa en el cerebro como una sinfon\u00eda. Si bien algunos m\u00fasicos (neuronas) pueden destacar por sus habilidades \u00fanicas (se\u00f1ales el\u00e9ctricas r\u00e1pidas), se necesita toda la orquesta para interpretar la composici\u00f3n. Si un m\u00fasico est\u00e1 desafinado, toda la orquesta puede sonar mal. Las c\u00e9lulas no neuronales no solo apoyan a las neuronas. Habilitan o mejoran sus habilidades. Cuando las c\u00e9lulas no neuronales funcionan mal, la operaci\u00f3n del cerebro y el comportamiento pueden verse afectados, como ocurre en las enfermedades neurodegenerativas e infecciosas.\u201c<\/p>\n

El proyecto se centrar\u00e1 en los astrocitos, uno de los tipos de c\u00e9lulas no neuronales m\u00e1s abundantes en el cerebro. En las \u00faltimas dos d\u00e9cadas, los estudios han indicado que los astrocitos desempe\u00f1an funciones cruciales en el desarrollo y las enfermedades del sistema nervioso. Sin embargo, se comprende mucho menos c\u00f3mo estas c\u00e9lulas interact\u00faan con las neuronas en el cerebro adulto sano.<\/p>\n

En Salk, Nimmerjahn ha desarrollado nuevas t\u00e9cnicas de microscop\u00eda para visualizar la din\u00e1mica estructural y funcional de c\u00e9lulas neuronales y no neuronales, tinciones espec\u00edficas de tipos celulares y herramientas de an\u00e1lisis de datos a gran escala. Utilizando estas tecnolog\u00edas, \u00e9l y sus colaboradores abordan preguntas de larga data sobre el papel de las c\u00e9lulas no neuronales en el sistema nervioso central humano sano o enfermo para proteger o restaurar su funci\u00f3n. Nimmerjahn emplear\u00e1 sus propias t\u00e9cnicas y otras de vanguardia para estudiar la comunicaci\u00f3n entre neuronas y astrocitos en este proyecto interdisciplinario.<\/p>\n

\u201cLa investigaci\u00f3n de Axel para comprender el papel de las c\u00e9lulas no neuronales ha proporcionado continuamente una perspectiva informativa sobre la forma en que entendemos la funci\u00f3n cerebral\u201d, afirma el presidente y profesor de Salk. Rusty Gage<\/a>. \u201cEstamos entusiasmados de ver sus colaboraciones m\u00e1s all\u00e1 de Salk y muy complacidos de que el programa BRAIN Circuit financiar\u00e1 este importante trabajo\u201d.\u201d<\/p>\n

Otros investigadores del equipo incluyen al profesor asociado Lin Tian de UC Davis, a la profesora asociada Cagla Eroglu de Duke University y al profesor asociado Guoqian Yu de Virginia Tech.<\/p>","protected":false},"featured_media":31659,"template":"","faculty":[89],"disease-research":[459,124],"class_list":["post-31560","disclosure","type-disclosure","status-publish","has-post-thumbnail","hentry","faculty-axel-nimmerjahn","disease-research-glial-biology","disease-research-neuroscience-and-neurological-disorders"],"acf":[],"yoast_head":"\nAxel Nimmerjahn leads research team awarded $11 million by the U19 Team-Research BRAIN Circuit Program - Salk Institute for Biological Studies<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.salk.edu\/es\/news-release\/axel-nimmerjahn-leads-research-team-awarded-11-million-by-the-u19-team-research-brain-circuit-program\/\" \/>\n<meta property=\"og:locale\" content=\"es_MX\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Axel Nimmerjahn leads research team awarded $11 million by the U19 Team-Research BRAIN Circuit Program - Salk Institute for Biological Studies\" \/>\n<meta property=\"og:description\" content=\"LA JOLLA\u2014Salk Associate Professor Axel Nimmerjahn is leading a research team that has been awarded $11.2 million by The Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative, an effort that aims to investigate overarching principles of brain circuit function, including sensation, perception, decision-making and motor control. 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