{"id":23200,"date":"2019-06-14T00:00:03","date_gmt":"2019-06-14T07:00:03","guid":{"rendered":"https:\/\/vermont.salk.edu\/?post_type=disclosure&p=23200"},"modified":"2023-12-07T16:42:52","modified_gmt":"2023-12-08T00:42:52","slug":"salk-scientist-diana-hargreaves-named-pew-stewart-scholar-for-innovative-cancer-research","status":"publish","type":"disclosure","link":"https:\/\/www.salk.edu\/es\/news-release\/salk-scientist-diana-hargreaves-named-pew-stewart-scholar-for-innovative-cancer-research\/","title":{"rendered":"Salk scientist Diana Hargreaves named Pew-Stewart Scholar for innovative cancer research"},"content":{"rendered":"

LA JOLLA \u2013 (June 14, 2019) Diana Hargreaves<\/a>, an assistant professor in Salk\u2019s Molecular and Cell Biology Laboratory, has been named a 2019 Becario Pew-Stewart para la Investigaci\u00f3n del C\u00e1ncer<\/a> as part of a partnership between the Pew Charitable Trusts and the Alexander and Margaret Stewart Trust. The scholars each receive $300,000 over four years to support their work focused on a better understanding of the causes, diagnosis and treatment of cancer.<\/p>\n

\u201cDiana is pushing the boundaries of cancer research by studying the protein complexes that organize our DNA, which are frequently mutated in cancer,\u201d says Salk President\u00a0Rusty Gage<\/a>. \u201cWe are excited and proud to have her groundbreaking work recognized by the Pew Charitable Trusts and the Alexander and Margaret Stewart Trust.\u201d<\/p>\n

\"Diana
Diana Hargreaves<\/p>\n

Haga clic aqu\u00ed<\/a> para obtener una imagen en alta resoluci\u00f3n.<\/p>\n

Cr\u00e9dito: Instituto Salk<\/figcaption><\/figure>\n

Hargreaves, who holds the Richard Heyman and Anne Daigle Endowed Developmental Chair, is one of the faculty involved in the Salk Iniciativa \u00abVencer al c\u00e1ncer\u00bb<\/a>, aiming to uncover new insights into the deadliest cancers. She studies epigenetic regulators, proteins that work to make specific regions of the genome more or less accessible for gene transcription. Unlike our fixed genome, the epigenome is dynamic, allowing cells to respond to developmental and external environmental cues. For example, she investigates a subunit of an epigenetic regulator (the SWI\/SNF complex) called ARID1A, which can be mutated in solid tumors such as in ovarian, bladder and colorectal cancer. By understanding the proteins\u2019 roles in driving cancer, she aims to find ways to reverse tumor progression.<\/p>\n

Hargreaves\u2019 work extends to include many different angles of cancer initiation and progression. As a Pew-Stewart Scholar, she proposes to study the role of the SWI\/SNF complex and other epigenetic regulators in controlling the activation of immune cells that infiltrate cancers. For instance, she seeks to examine the possibility of reprogramming tumor-associated macrophages (TAMs) to alert the immune system of a tumor instead of promoting the spread of cancer. Her studies have the potential to enhance the current state of cancer immunotherapy by uncovering a new set of therapeutic targets designed to boost immune system defenses against tumors.<\/p>\n

The Pew-Stewart Scholars Program for Cancer Research is a national initiative designed to support promising early career scientists whose research will accelerate discovery and advance progress to a cure for cancer. The Stewart Trust has invested in innovative, cutting-edge cancer research and scientists for over 15 years. Through this partnership, The Pew-Stewart Scholars for Cancer Research have tremendous potential to solve some of cancer\u2019s weightiest challenges.<\/p>\n

Acerca de los fideicomisos:<\/strong><\/p>\n

The Pew Charitable Trusts is driven by the power of knowledge to solve today\u2019s most challenging problems. Learn more at\u00a0pewtrusts.org<\/a>.<\/p>\n

The Alexander and Margaret Stewart Trust is a charitable foundation supporting nonprofit organizations that research, treat, and prevent cancer and pediatric illnesses. Learn more at\u00a0stewart-trust.org<\/a>.<\/p>\n

Acerca del Instituto Salk de Estudios Biol\u00f3gicos:<\/strong><\/p>\n

Cada cura tiene un punto de partida. El Instituto Salk encarna la misi\u00f3n de Jonas Salk de atreverse a convertir los sue\u00f1os en realidad. Sus cient\u00edficos, de renombre internacional y galardonados, exploran los cimientos mismos de la vida, buscando nuevas comprensiones en neurociencia, gen\u00e9tica, inmunolog\u00eda, biolog\u00eda vegetal y m\u00e1s. El Instituto es una organizaci\u00f3n independiente sin fines de lucro y un hito arquitect\u00f3nico: peque\u00f1o por elecci\u00f3n, \u00edntimo por naturaleza e intr\u00e9pido ante cualquier desaf\u00edo. Ya sea c\u00e1ncer o Alzheimer, envejecimiento o diabetes, el Instituto Salk es donde comienzan las curas. Obtenga m\u00e1s informaci\u00f3n en: salk.edu.<\/p>","protected":false},"featured_media":0,"template":"","faculty":[74],"disease-research":[46,447],"class_list":["post-23200","disclosure","type-disclosure","status-publish","hentry","faculty-diana-hargreaves","disease-research-cancer-biology","disease-research-colorectal-cancer"],"acf":[],"yoast_head":"\nSalk scientist Diana Hargreaves named Pew-Stewart Scholar for innovative cancer research - Salk Institute for Biological Studies<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.salk.edu\/es\/news-release\/salk-scientist-diana-hargreaves-named-pew-stewart-scholar-for-innovative-cancer-research\/\" \/>\n<meta property=\"og:locale\" content=\"es_MX\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Salk scientist Diana Hargreaves named Pew-Stewart Scholar for innovative cancer research - Salk Institute for Biological Studies\" \/>\n<meta property=\"og:description\" content=\"LA JOLLA \u2013 (June 14, 2019) Diana Hargreaves, an assistant professor in Salk\u2019s Molecular and Cell Biology Laboratory, has been named a 2019 Pew-Stewart Scholar for Cancer Research as part of a partnership between the Pew Charitable Trusts and the Alexander and Margaret Stewart Trust. The scholars each receive $300,000 over four years to support their work focused on a better understanding of the causes, diagnosis and treatment of cancer.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.salk.edu\/es\/news-release\/salk-scientist-diana-hargreaves-named-pew-stewart-scholar-for-innovative-cancer-research\/\" \/>\n<meta property=\"og:site_name\" content=\"Salk Institute for Biological Studies\" \/>\n<meta property=\"article:modified_time\" content=\"2023-12-08T00:42:52+00:00\" \/>\n<meta property=\"og:image\" content=\"http:\/\/www.salk.edu\/wp-content\/uploads\/2019\/06\/Diana_Hargreaves_1500-300x450.jpg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.salk.edu\\\/news-release\\\/salk-scientist-diana-hargreaves-named-pew-stewart-scholar-for-innovative-cancer-research\\\/\",\"url\":\"https:\\\/\\\/www.salk.edu\\\/news-release\\\/salk-scientist-diana-hargreaves-named-pew-stewart-scholar-for-innovative-cancer-research\\\/\",\"name\":\"Salk scientist Diana Hargreaves named Pew-Stewart Scholar for innovative cancer research - Salk Institute for Biological Studies\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.salk.edu\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.salk.edu\\\/news-release\\\/salk-scientist-diana-hargreaves-named-pew-stewart-scholar-for-innovative-cancer-research\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.salk.edu\\\/news-release\\\/salk-scientist-diana-hargreaves-named-pew-stewart-scholar-for-innovative-cancer-research\\\/#primaryimage\"},\"thumbnailUrl\":\"http:\\\/\\\/www.salk.edu\\\/wp-content\\\/uploads\\\/2019\\\/06\\\/Diana_Hargreaves_1500-300x450.jpg\",\"datePublished\":\"2019-06-14T07:00:03+00:00\",\"dateModified\":\"2023-12-08T00:42:52+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.salk.edu\\\/news-release\\\/salk-scientist-diana-hargreaves-named-pew-stewart-scholar-for-innovative-cancer-research\\\/#breadcrumb\"},\"inLanguage\":\"es-MX\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.salk.edu\\\/news-release\\\/salk-scientist-diana-hargreaves-named-pew-stewart-scholar-for-innovative-cancer-research\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"es-MX\",\"@id\":\"https:\\\/\\\/www.salk.edu\\\/news-release\\\/salk-scientist-diana-hargreaves-named-pew-stewart-scholar-for-innovative-cancer-research\\\/#primaryimage\",\"url\":\"http:\\\/\\\/www.salk.edu\\\/wp-content\\\/uploads\\\/2019\\\/06\\\/Diana_Hargreaves_1500-300x450.jpg\",\"contentUrl\":\"http:\\\/\\\/www.salk.edu\\\/wp-content\\\/uploads\\\/2019\\\/06\\\/Diana_Hargreaves_1500-300x450.jpg\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.salk.edu\\\/news-release\\\/salk-scientist-diana-hargreaves-named-pew-stewart-scholar-for-innovative-cancer-research\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/www.salk.edu\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Salk scientist Diana Hargreaves named Pew-Stewart Scholar for innovative cancer research\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.salk.edu\\\/#website\",\"url\":\"https:\\\/\\\/www.salk.edu\\\/\",\"name\":\"Salk Institute for Biological Studies\",\"description\":\"The Power of Science\",\"publisher\":{\"@id\":\"https:\\\/\\\/www.salk.edu\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.salk.edu\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"es-MX\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/www.salk.edu\\\/#organization\",\"name\":\"Salk Institute for Biological Studies\",\"url\":\"https:\\\/\\\/www.salk.edu\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"es-MX\",\"@id\":\"https:\\\/\\\/www.salk.edu\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"http:\\\/\\\/www.salk.edu\\\/wp-content\\\/uploads\\\/2023\\\/03\\\/salk_logo_696.jpg\",\"contentUrl\":\"http:\\\/\\\/www.salk.edu\\\/wp-content\\\/uploads\\\/2023\\\/03\\\/salk_logo_696.jpg\",\"width\":696,\"height\":696,\"caption\":\"Salk Institute for Biological Studies\"},\"image\":{\"@id\":\"https:\\\/\\\/www.salk.edu\\\/#\\\/schema\\\/logo\\\/image\\\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Salk scientist Diana Hargreaves named Pew-Stewart Scholar for innovative cancer research - Salk Institute for Biological Studies","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.salk.edu\/es\/news-release\/salk-scientist-diana-hargreaves-named-pew-stewart-scholar-for-innovative-cancer-research\/","og_locale":"es_MX","og_type":"article","og_title":"Salk scientist Diana Hargreaves named Pew-Stewart Scholar for innovative cancer research - Salk Institute for Biological Studies","og_description":"LA JOLLA \u2013 (June 14, 2019) Diana Hargreaves, an assistant professor in Salk\u2019s Molecular and Cell Biology Laboratory, has been named a 2019 Pew-Stewart Scholar for Cancer Research as part of a partnership between the Pew Charitable Trusts and the Alexander and Margaret Stewart Trust. The scholars each receive $300,000 over four years to support their work focused on a better understanding of the causes, diagnosis and treatment of cancer.","og_url":"https:\/\/www.salk.edu\/es\/news-release\/salk-scientist-diana-hargreaves-named-pew-stewart-scholar-for-innovative-cancer-research\/","og_site_name":"Salk Institute for Biological Studies","article_modified_time":"2023-12-08T00:42:52+00:00","og_image":[{"url":"http:\/\/www.salk.edu\/wp-content\/uploads\/2019\/06\/Diana_Hargreaves_1500-300x450.jpg","type":"","width":"","height":""}],"twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"3 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.salk.edu\/news-release\/salk-scientist-diana-hargreaves-named-pew-stewart-scholar-for-innovative-cancer-research\/","url":"https:\/\/www.salk.edu\/news-release\/salk-scientist-diana-hargreaves-named-pew-stewart-scholar-for-innovative-cancer-research\/","name":"Salk scientist Diana Hargreaves named Pew-Stewart Scholar for innovative cancer research - Salk Institute for Biological Studies","isPartOf":{"@id":"https:\/\/www.salk.edu\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.salk.edu\/news-release\/salk-scientist-diana-hargreaves-named-pew-stewart-scholar-for-innovative-cancer-research\/#primaryimage"},"image":{"@id":"https:\/\/www.salk.edu\/news-release\/salk-scientist-diana-hargreaves-named-pew-stewart-scholar-for-innovative-cancer-research\/#primaryimage"},"thumbnailUrl":"http:\/\/www.salk.edu\/wp-content\/uploads\/2019\/06\/Diana_Hargreaves_1500-300x450.jpg","datePublished":"2019-06-14T07:00:03+00:00","dateModified":"2023-12-08T00:42:52+00:00","breadcrumb":{"@id":"https:\/\/www.salk.edu\/news-release\/salk-scientist-diana-hargreaves-named-pew-stewart-scholar-for-innovative-cancer-research\/#breadcrumb"},"inLanguage":"es-MX","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.salk.edu\/news-release\/salk-scientist-diana-hargreaves-named-pew-stewart-scholar-for-innovative-cancer-research\/"]}]},{"@type":"ImageObject","inLanguage":"es-MX","@id":"https:\/\/www.salk.edu\/news-release\/salk-scientist-diana-hargreaves-named-pew-stewart-scholar-for-innovative-cancer-research\/#primaryimage","url":"http:\/\/www.salk.edu\/wp-content\/uploads\/2019\/06\/Diana_Hargreaves_1500-300x450.jpg","contentUrl":"http:\/\/www.salk.edu\/wp-content\/uploads\/2019\/06\/Diana_Hargreaves_1500-300x450.jpg"},{"@type":"BreadcrumbList","@id":"https:\/\/www.salk.edu\/news-release\/salk-scientist-diana-hargreaves-named-pew-stewart-scholar-for-innovative-cancer-research\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.salk.edu\/"},{"@type":"ListItem","position":2,"name":"Salk scientist Diana Hargreaves named Pew-Stewart Scholar for innovative cancer research"}]},{"@type":"WebSite","@id":"https:\/\/www.salk.edu\/#website","url":"https:\/\/www.salk.edu\/","name":"Instituto Salk de Estudios Biol\u00f3gicos","description":"El Poder de la Ciencia","publisher":{"@id":"https:\/\/www.salk.edu\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.salk.edu\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"es-MX"},{"@type":"Organization","@id":"https:\/\/www.salk.edu\/#organization","name":"Instituto Salk de Estudios Biol\u00f3gicos","url":"https:\/\/www.salk.edu\/","logo":{"@type":"ImageObject","inLanguage":"es-MX","@id":"https:\/\/www.salk.edu\/#\/schema\/logo\/image\/","url":"http:\/\/www.salk.edu\/wp-content\/uploads\/2023\/03\/salk_logo_696.jpg","contentUrl":"http:\/\/www.salk.edu\/wp-content\/uploads\/2023\/03\/salk_logo_696.jpg","width":696,"height":696,"caption":"Salk Institute for Biological Studies"},"image":{"@id":"https:\/\/www.salk.edu\/#\/schema\/logo\/image\/"}}]}},"ACF":{"paper_url":"","journal_title":"","paper_author_list":"","doi":"","paper_title":"","subhead":"","home_photo":"","listing_photo":"","legacy_boilerplate":[],"hide_boilerplate":["Hide"],"disable_date":false,"listing_excerpt":"","descriptive_blurb":"","has_journal_cover":false,"og_image_override":false,"gallery":false},"_links":{"self":[{"href":"https:\/\/www.salk.edu\/es\/wp-json\/wp\/v2\/disclosure\/23200","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.salk.edu\/es\/wp-json\/wp\/v2\/disclosure"}],"about":[{"href":"https:\/\/www.salk.edu\/es\/wp-json\/wp\/v2\/types\/disclosure"}],"version-history":[{"count":3,"href":"https:\/\/www.salk.edu\/es\/wp-json\/wp\/v2\/disclosure\/23200\/revisions"}],"predecessor-version":[{"id":23212,"href":"https:\/\/www.salk.edu\/es\/wp-json\/wp\/v2\/disclosure\/23200\/revisions\/23212"}],"wp:attachment":[{"href":"https:\/\/www.salk.edu\/es\/wp-json\/wp\/v2\/media?parent=23200"}],"wp:term":[{"taxonomy":"faculty","embeddable":true,"href":"https:\/\/www.salk.edu\/es\/wp-json\/wp\/v2\/faculty?post=23200"},{"taxonomy":"disease-research","embeddable":true,"href":"https:\/\/www.salk.edu\/es\/wp-json\/wp\/v2\/disease-research?post=23200"}],"curies":[{"name":"la hora de","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}