Juan Carlos Izpis\u00faa Belmonte<\/a>, Ph.D., was appointed as the inaugural holder of the Roger Guillemin Chair.<\/p>\n\nEach chair holder is known for their tireless groundbreaking research that impacts lives. Dr. Hunter discovered a biological process that can trigger the uncontrolled division of cells\u2014 shedding much needed light on cancer. Dr. Izpis\u00faa Belmonte is a trailblazer in the areas of regenerative medicine, birth defects, and gene development.<\/p>\n
\nBoth the endowed chairs were established in full through a generous gift from Joan Klein Jacobs and Irwin Jacobs funding each chair at $3 million each\u2014as part of the Jacobs Chair Challenge. Launched in 2008 with a $10 million matching fund, the Jacobs Chair Challenge encourages and enables donors to create prestigious, permanent chairs in support of senior faculty members at Salk.<\/p>\n
\nOn April 14, 2011 the Jacobses announced they were giving an additional $5 million donation due to the successful response in donor funding of the first ten chairs. With nine of the original research chairs already spoken for, the additional five $1 million contributions will go toward the creation of five new chairs, a challenge format designed to inspire others to give.<\/p>\n
\n“Irwin and Joan’s leadership is extraordinary,” stated Salk president William R. Brody. “Their honoring Renato and Roger and having two distinguished scientific leaders as inaugural holders of these endowed chairs, is a wonderful example of why the Salk Institute remains at the forefront of life changing discovery.”<\/p>\n
\nTony Hunter<\/strong>, an American Cancer Society Professor in the Molecular and Cell Biology Laboratory and director of the Salk Institute Cancer Center, explores how mutations in genes that control growth lead to cancer and has made crucial contributions in understanding how signals that stimulate or regulate cell development are routed.<\/p>\n\nIn 1979, Hunter’s lab made a groundbreaking discovery that a biological process called tyrosine phosphorylation is a chemical “on-off” switch that can trigger the uncontrolled division of cells\u2014the hallmark of many cancers. This important signaling mechanism, which proved to be the underlying cause of many types of human cancer, revolutionized cancer research and, ultimately, resulted in a new approach to treatment of the disease and the development of several innovative therapies as researchers found ways to inhibit the special proteins called tyrosine kinases that are responsible for tyrosine phosphorylation.<\/p>\n
\nHunter is a member of the National Academy of Sciences and a fellow of the Royal Society of London. His extraordinary work has garnered international acclaim and numerous awards including the 2006 Robert J. and Claire Pasarow Award for Cancer Research; the 2005 Wolf Prize in Medicine, Israel’s top recognition for achievements in the interest of humanity; the 2004 Louisa Gross Horwitz Prize, a leading national award for scientific achievement; and Japan’s 2001 Keio Medical Science Prize.<\/p>\n
\n“I am honored to have been selected as the first holder of the Dulbecco Chair, particularly because I am Renato’s scientific “grandson”, having trained with Walter Eckhart, who was himself a postdoctoral fellow with Renato at the Salk,” said Hunter.<\/p>\n
\nJuan Carlos Izpis\u00faa Belmonte<\/strong>, a professor in the Gene Expression Laboratory at Salk has been at the forefront of developmental biology research and studies how genes and molecules orchestrate the development of an embryo. Through the years he has produced novel cutting-edge results, such as uncovering the genetic network involved in a broad variety of organ embryogenesis, as well as identifying how molecular guide posts direct organs to their rightful place along the body axes in the developing embryo.<\/p>\n\nHis work has given insight into the molecular basis implicated during organ regeneration in higher vertebrates, the differentiation of human stem cells into various tissues, and the molecular basis underlying somatic cell reprogramming. In addition to improving our knowledge on early human development, the research activities of Dr. Izpis\u00faa Belmonte’s laboratory are relevant to understanding the causes that underlie human birth defects, as well as to the future development of regenerative medicine.<\/p>\n
\nDr. Izpis\u00faa Belmonte has received many notable honors and awards, including the William J. Clinton Presidential Award, the Pew Scholar Award, the National Science Foundation Creativity Award, and the American Heart Association Established Investigator Award, for his endeavors in these fields.<\/p>\n
\n“To be chosen as the inaugural holder of The Guillemin Chair is an enormous privilege for me,” said Izpis\u00faa Belmonte. “Roger Guillemin is the embodiment of a scientific pioneer and visionary and I am delighted and honored to be recognized by my peers in this way.”\n<\/p>\n
\nAcerca del Instituto Salk de Estudios Biol\u00f3gicos:<\/strong>
El Instituto Salk de Estudios Biol\u00f3gicos es una de las instituciones de investigaci\u00f3n b\u00e1sica m\u00e1s destacadas del mundo, donde un cuerpo docente de prestigio internacional investiga cuestiones fundamentales de las ciencias de la vida en un entorno \u00fanico, colaborativo y creativo. Centrados tanto en el descubrimiento como en la formaci\u00f3n de las futuras generaciones de investigadores, los cient\u00edficos del Salk realizan contribuciones revolucionarias a nuestra comprensi\u00f3n del c\u00e1ncer, el envejecimiento, el Alzheimer, la diabetes y las enfermedades infecciosas mediante el estudio de la neurociencia, la gen\u00e9tica, la biolog\u00eda celular y vegetal, y otras disciplinas relacionadas.<\/p>\n\nLos logros del cuerpo docente han sido reconocidos con numerosos galardones, entre los que se incluyen premios Nobel y la pertenencia a la Academia Nacional de Ciencias. Fundado en 1960 por el Dr. Jonas Salk, pionero en la vacuna contra la poliomielitis, el Instituto es una organizaci\u00f3n independiente sin fines de lucro y un hito arquitect\u00f3nico.<\/p>","protected":false},"featured_media":0,"template":"","faculty":[],"disease-research":[],"class_list":["post-2098","disclosure","type-disclosure","status-publish","hentry"],"acf":[],"yoast_head":"\n
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