{"id":20405,"date":"2018-10-09T10:26:03","date_gmt":"2018-10-09T17:26:03","guid":{"rendered":"https:\/\/vermont.salk.edu\/?post_type=disclosure&p=20405"},"modified":"2019-01-17T09:58:45","modified_gmt":"2019-01-17T17:58:45","slug":"dannielle-engle-rising-star-in-pancreatic-cancer-research-to-join-salk-institute","status":"publish","type":"disclosure","link":"https:\/\/www.salk.edu\/es\/news-release\/dannielle-engle-rising-star-in-pancreatic-cancer-research-to-join-salk-institute\/","title":{"rendered":"Dannielle Engle, estrella emergente en la investigaci\u00f3n de c\u00e1ncer de p\u00e1ncreas, se unir\u00e1 al Salk Institute"},"content":{"rendered":"

LA JOLLA\u2014El Instituto Salk tiene el honor de dar la bienvenida de regreso a Dannielle Engle al Salk como profesora asistente en el Centro de C\u00e1ncer Salk. Actualmente es investigadora principal en el Laboratorio Cold Spring Harbor en Nueva York, donde se enfoca en la detecci\u00f3n temprana y el tratamiento del c\u00e1ncer de p\u00e1ncreas. Engle realiz\u00f3 investigaciones en el laboratorio del Profesor del Salk Geoffrey Wahl<\/a> durante seis a\u00f1os como parte de su programa doctoral en UC San Diego.<\/p>\n

\"Dannielle
Dannielle Engle<\/p>\n

Haga clic aqu\u00ed<\/a> para obtener una imagen en alta resoluci\u00f3n. <\/p>\n

Cr\u00e9dito: Cold Spring Harbor Laboratory<\/figcaption><\/figure>\n

\u201cLa investigaci\u00f3n de Dannielle Engle sobre el c\u00e1ncer de mama cuando era estudiante de posgrado en el laboratorio Wahl fue excepcional\u201d, dice el presidente del Salk, Rusty Gage. \u201cSu transici\u00f3n al c\u00e1ncer de p\u00e1ncreas, que comenz\u00f3 en el Salk, ha resultado ser igual de innovadora. Estamos encantados de contar con una cient\u00edfica en la primera etapa de su carrera de su calibre uni\u00e9ndose al Centro de C\u00e1ncer Salk\u201d.\u201d<\/p>\n

El c\u00e1ncer de p\u00e1ncreas es uno de los c\u00e1nceres m\u00e1s mort\u00edferos debido a que es dif\u00edcil de detectar y especialmente resistente al tratamiento. Como parte de su formaci\u00f3n postdoctoral con David A. Tuveson en el Cambridge Research Institute (Reino Unido) y el Cold Spring Harbor Laboratory, Engle desarroll\u00f3 cultivos de organoides pancre\u00e1ticos en miniatura (\u201corganoides\u201d) con c\u00e9lulas humanas y de rat\u00f3n para identificar biomarcadores y tratamientos para el c\u00e1ncer de p\u00e1ncreas.<\/p>\n

\u201cEl trabajo del Dr. Engle es muy singular, ya que combina modelos gen\u00e9ticos para estudiar la detecci\u00f3n temprana y biomarcadores que se utilizan cl\u00ednicamente en an\u00e1lisis de sangre para personas que podr\u00edan tener o desarrollar c\u00e1ncer de p\u00e1ncreas\u201d, dice Salk Cancer Center<\/a> Director Reuben Shaw<\/a>, quien ostenta la C\u00e1tedra William R. Brody. \u201cElla aporta una inmediatez en el cuidado del paciente y nuevas perspectivas sobre el c\u00e1ncer de p\u00e1ncreas, la detecci\u00f3n temprana y la prevenci\u00f3n del c\u00e1ncer que ayudan a mantener al Salk a la vanguardia de la investigaci\u00f3n traslacional. Estamos agradecidos a Daniel y Martina Lewis por su generoso donativo filantr\u00f3pico que hizo posible esta contrataci\u00f3n, apoyando nuestra misi\u00f3n de reclutar a las mejores personas del pa\u00eds y ampliar el alcance de nuestra misi\u00f3n de investigaci\u00f3n.\u201d<\/p>\n

El Salk Cancer Center (uno de solo siete centros de investigaci\u00f3n b\u00e1sica designados por el Instituto Nacional del C\u00e1ncer en el pa\u00eds) lanz\u00f3 recientemente una campa\u00f1a de recaudaci\u00f3n de fondos de cinco a\u00f1os y $55 millones de d\u00f3lares llamada Conquering Cancer Initiative para abordar cinco de los c\u00e1nceres m\u00e1s mortales, uno de los cuales es el c\u00e1ncer de p\u00e1ncreas. El reclutamiento de Engle fue posible en parte gracias a los patrocinadores de la iniciativa, incluido el presidente de la junta de Salk, Dan Lewis, y su esposa, Martina Lewis, quienes recientemente agregaron un regalo de $2 millones de d\u00f3lares a un compromiso previo de un mill\u00f3n de d\u00f3lares con el prop\u00f3sito de reclutar acad\u00e9micos destacados.<\/p>\n

\u201cLa Dra. Engle es muy merecedora de este puesto debido a su excepcional trabajo para desarrollar mejores estrategias de detecci\u00f3n temprana y tratamiento para el c\u00e1ncer de p\u00e1ncreas\u201d, afirma Wahl, quien es subdirectora del Centro de C\u00e1ncer Salk y ocupa la C\u00e1tedra Daniel y Martina Lewis. \u201cComo persona colaboradora y en\u00e9rgica, ser\u00e1 una gran incorporaci\u00f3n al s\u00f3lido equipo de investigaci\u00f3n del c\u00e1ncer de p\u00e1ncreas del Centro de C\u00e1ncer Salk y a nuestra facultad. Como su mentora de posgrado, no podr\u00eda estar m\u00e1s orgullosa de darle la bienvenida de regreso al Salk como colega\u201d.\u201d<\/p>\n

En cuanto a por qu\u00e9 eligi\u00f3 regresar a Salk, Engle dice: \u201cSalk es un lugar donde las divisiones y los egos no impiden abordar problemas grandes e importantes. Necesitamos hacer m\u00e1s para impactar el cuidado de los pacientes con c\u00e1ncer de p\u00e1ncreas; los enfoques utilizados en el pasado para tratar otros tipos de c\u00e1ncer simplemente no est\u00e1n funcionando. Estar en Salk permitir\u00e1 la b\u00fasqueda de ideas creativas y arriesgadas que desaf\u00eden los paradigmas existentes, que es lo que necesitamos para poder ayudar a las personas\u201d.\u201d<\/p>\n

Engle tiene una licenciatura en ciencias biol\u00f3gicas y estudios asi\u00e1ticos de la Universidad Northwestern y un doctorado en ciencias biol\u00f3gicas de la Universidad de California San Diego. Es destinataria de una beca del Programa de Investigaci\u00f3n sobre C\u00e1ncer de Mama de California, una beca del Canciller de UC San Diego y un premio de transici\u00f3n profesional de los Institutos Nacionales de Salud\/Instituto Nacional del C\u00e1ncer, entre otros honores. Comienza su cargo en enero de 2019.<\/p>","protected":false},"featured_media":20407,"template":"","faculty":[345],"disease-research":[46],"class_list":["post-20405","disclosure","type-disclosure","status-publish","has-post-thumbnail","hentry","faculty-dannielle-engle","disease-research-cancer-biology"],"acf":[],"yoast_head":"\nDannielle Engle, rising star in pancreatic cancer research, to join Salk Institute - Salk Institute for Biological Studies<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.salk.edu\/es\/news-release\/dannielle-engle-rising-star-in-pancreatic-cancer-research-to-join-salk-institute\/\" \/>\n<meta property=\"og:locale\" content=\"es_MX\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Dannielle Engle, rising star in pancreatic cancer research, to join Salk Institute - Salk Institute for Biological Studies\" \/>\n<meta property=\"og:description\" content=\"LA JOLLA\u2014The Salk Institute is honored to welcome Dannielle Engle back to Salk as an assistant professor in the Salk Cancer Center. 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