{"id":2026,"date":"2010-03-22T00:00:00","date_gmt":"2010-03-22T07:00:00","guid":{"rendered":"https:\/\/vermont.salk.edu\/news-release\/gatsby-charitable-foundation-awards-4-million-to-salk-uc-san-diego-consortium-to-study-brain-circuitry\/"},"modified":"2010-03-22T00:00:00","modified_gmt":"2010-03-22T07:00:00","slug":"gatsby-charitable-foundation-awards-4-million-to-salk-uc-san-diego-consortium-to-study-brain-circuitry","status":"publish","type":"disclosure","link":"https:\/\/www.salk.edu\/es\/news-release\/gatsby-charitable-foundation-awards-4-million-to-salk-uc-san-diego-consortium-to-study-brain-circuitry\/","title":{"rendered":"Gatsby Charitable Foundation awards $4 million to Salk-UC San Diego consortium to study brain circuitry"},"content":{"rendered":"<p>LA JOLLA\u2014A new consortium of four research teams from the Salk Institute for Biological Studies and the University of California, San Diego has been selected by the Gatsby Charitable Foundation, based in the United Kingdom, to receive a $4 million grant over five years to study neuronal circuits underlying higher brain function. <\/p>\n<p>\nThe teams headed by Salk researchers <a href=\"\/es\/faculty\/callaway.html\/\">Edward M. Callaway<\/a>, Ph.D., and <a href=\"\/es\/faculty\/reynolds.html\/\">John H. Reynolds<\/a>, Ph.D., and UC San Diego professors Anirvan Ghosh, Ph.D., and Massimo Scanziani, Ph.D., look forward to formalizing a longstanding relationship developed through overlapping research interests and facilitated by geographical proximity.<\/p>\n<p>\n&#8220;The grant from the Gatsby Charitable Foundation creates a tremendous opportunity to work closer together than ever before,&#8221; says Callaway, of the Salk Institute. &#8220;It allows us to capitalize on the unique strengths we have as a team.&#8221;<\/p>\n<p>\nHigher brain functions, such as visual perception and attention, are the result of the coordinated activity of neurons in the cerebral cortex. But a lack of detailed knowledge of how different elements and cell types interact to give rise to sensations and thought has limited understanding of the neural mechanisms that underlie cortical functions. <\/p>\n<p>\nThe collaborating teams&#8217; efforts will focus on developing and using genetic tools that will allow them to manipulate specific cell types in the brain to tease apart their contributions to higher order brain function. <\/p>\n<p>\n&#8220;The human brain with its unrivaled complexity is biology&#8217;s last frontier,&#8221; says UC San Diego researcher Ghosh. &#8220;Thanks to the support of the Gatsby Foundation, we expect to greatly expand the understanding of brain circuitry. This will in turn allow us to explore the brain&#8217;s ability to adapt and rewire, as well as its remarkable capacity to learn and remember.&#8221;<\/p>\n<p>\nAdds Callaway: &#8220;This collaborative study has the potential to provide us with exciting insight into how the brain makes us who we are.&#8221;<\/p>\n<ul>\n<li><strong>Edward M. Callaway, Ph.D.,<\/strong> a professor in the Systems Neurobiology Laboratories at the Salk Institute, studies the organization and function of neural circuits in the visual cortex to better understand how specific neural components contribute to the computations that give rise to visual perception and to elucidate the basic neural mechanisms that underlie cortical function.<\/li>\n<li><strong>Anirvan Ghosh, Ph.D.,<\/strong> a professor in UC San Diego&#8217;s Division of Biological Sciences and chair of the Division&#8217;s Neurobiology section, is interested in understanding the mechanisms that allow the developing brain to self-organize into functional circuits.<\/li>\n<li><strong>John H. Reynolds, Ph.D.,<\/strong> an associate professor in the Systems Neurobiology Laboratories at the Salk Institute seeks to understand the fundamental nature of the computations that are carried out by the neocortex, including the computations that enable us to attend to sensory stimuli, and to understand how and why these computations fail in brain disease.\n<\/li>\n<li><strong>Massimo Scanziani, Ph.D.,<\/strong> a professor in the UC San Diego Division of Biological Sciences&#8217; section of Neurobiology and Howard Hughes Medical Institute investigator, studies the mechanisms by which elementary circuits operate in the brain. His work aims to reveal the function and logic by which basic building blocks of cortical architecture orchestrate cortical activity, which gives rise to all thought and sensation.<\/li>\n<\/ul>\n<p><strong>About the Gatsby Charitable Foundation<\/strong><br \/>\nEstablished in 1967 by noted philanthropist Lord Sainsbury of Turville, the Gatsby Charitable Foundation is a London-based, endowed grant-making trust. Set up to provide funding for charitable causes, the Gatsby Charitable Foundation currently focuses on plant science, neuroscience, technical education, mental health in the criminal justice system, environmentally sustainable development and poverty alleviation in developing countries as well as the arts.  Learn more at <a href=\"http:\/\/www.gatsby.org.uk\">www.gatsby.org.uk<\/a>.<\/p>\n<p><strong>Acerca del Instituto Salk de Estudios Biol\u00f3gicos<\/strong><br \/>\nEl Instituto Salk de Estudios Biol\u00f3gicos es una de las instituciones de investigaci\u00f3n b\u00e1sica m\u00e1s destacadas del mundo, donde un cuerpo docente de prestigio internacional investiga cuestiones fundamentales de las ciencias de la vida en un entorno \u00fanico, colaborativo y creativo. Centrados tanto en el descubrimiento como en la formaci\u00f3n de las futuras generaciones de investigadores, los cient\u00edficos del Salk realizan contribuciones revolucionarias a nuestra comprensi\u00f3n del c\u00e1ncer, el envejecimiento, el Alzheimer, la diabetes y las enfermedades infecciosas mediante el estudio de la neurociencia, la gen\u00e9tica, la biolog\u00eda celular y vegetal, y otras disciplinas relacionadas.<\/p>\n<p>\nLos logros del cuerpo docente han sido reconocidos con numerosos galardones, entre los que se incluyen premios Nobel y la pertenencia a la Academia Nacional de Ciencias. Fundado en 1960 por el Dr. Jonas Salk, pionero en la vacuna contra la poliomielitis, el Instituto es una organizaci\u00f3n independiente sin fines de lucro y un hito arquitect\u00f3nico.<\/p>\n<p>\n<strong>About UC San Diego<\/strong><\/p>\n<p>Founded in 1960, the University of California, San Diego is ranked the best value public university in California by <em>Kiplinger&#8217;s Personal Finance<\/em> magazine and the 7th best public university in the nation by <em>U.S. News and World Report<\/em>. Named the &#8220;hottest&#8221; institution to study science by <em>Newsweek<\/em>, UC San Diego is one of the nation&#8217;s most accomplished research universities, widely acknowledged for its local impact, national influence and global reach. Renowned for its collaborative, diverse and cross-disciplinary ethos that transcends traditional boundaries in science, arts and the humanities, the university attracts stellar faculty, students and staff.  For more information, please visit <a href=\"http:\/\/www.ucsd.edu\">www.ucsd.edu<\/a>.<\/p>","protected":false},"featured_media":0,"template":"","faculty":[84,107],"disease-research":[],"class_list":["post-2026","disclosure","type-disclosure","status-publish","hentry","faculty-edward-callaway","faculty-john-reynolds"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Gatsby Charitable Foundation awards $4 million to Salk-UC San Diego consortium to study brain circuitry - Salk Institute for Biological Studies<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.salk.edu\/es\/news-release\/gatsby-charitable-foundation-awards-4-million-to-salk-uc-san-diego-consortium-to-study-brain-circuitry\/\" \/>\n<meta property=\"og:locale\" content=\"es_MX\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Gatsby Charitable Foundation awards $4 million to Salk-UC San Diego consortium to study brain circuitry - 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