{"id":1976,"date":"2009-05-29T00:00:00","date_gmt":"2009-05-29T07:00:00","guid":{"rendered":"https:\/\/vermont.salk.edu\/news-release\/salk-scientist-inder-verma-to-receive-2009-outstanding-achievement-award-from-american-society-of-gene-therapy\/"},"modified":"2009-05-29T00:00:00","modified_gmt":"2009-05-29T07:00:00","slug":"salk-scientist-inder-verma-to-receive-2009-outstanding-achievement-award-from-american-society-of-gene-therapy","status":"publish","type":"disclosure","link":"https:\/\/www.salk.edu\/es\/news-release\/salk-scientist-inder-verma-to-receive-2009-outstanding-achievement-award-from-american-society-of-gene-therapy\/","title":{"rendered":"Salk Scientist Inder Verma to Receive 2009 Outstanding Achievement Award from American Society of Gene Therapy"},"content":{"rendered":"

La Jolla, CA\u2014Salk Professor Inder M. Verma<\/a>, Ph.D., one of the world’s leading authorities on the development and use of engineered viruses for gene therapy, has been named the 2009 recipient of the American Society of Gene Therapy’s Outstanding Achievement Award. The award recognizes an ASGT member who has conducted groundbreaking research or achieved a lifetime of significant scientific contributions to the field of gene therapy. Verma is only the second scientist honored with the society’s Outstanding Achievement Award, which debuted in 2008.\n <\/p>\n

\nVerma, the American Cancer Society Professor of Molecular Biology in the Salk Institute’s Laboratory of Genetics and holder of the Irwin Mark Jacobs Chair in Exemplary Life Science, pioneered the use of stripped-down versions of viruses, in particular HIV, to ferry intact versions of genes that are defective or missing to cells throughout the body. His innovations revolutionized gene therapy, stem cell and cancer research, and other areas of molecular biology. He will receive the award in San Diego, at the society’s annual meeting May 27-30, 2009.\n <\/p>\n

\nWhen Verma and his team conducted the first successful study to use viruses to deliver therapeutic genes into cells in 1983, the news made the front page of the New York Times. The research demonstrated that a genetic disease, in this case, Lesch-Nyhans syndrome, could be corrected in a Petri dish using retroviruses-a family of viruses that can insert themselves into a cell’s genome-as the vector, or delivery vehicle. They went on to use viral vectors to introduce genes into animals, correcting such genetic diseases as hemophilia and severe combined immunodeficiency syndrome (SCID), or “bubble boy disease.” Currently, more than 60 percent of all gene therapy trials worldwide rely on viruses to transport their genetic payload into cells.\n <\/p>\n

\nPrior to 1996, viruses used as gene delivery vehicles could only infect dividing cells, which left out the vast majority of cells in the body. That year, however, Verma’s group modified the human immunodeficiency virus (HIV), a member of the retrovirus family, which is capable of infecting nondividing cells, to deliver genes safely and efficiently into a wide variety of cells. Using this new method, they were able to influence a number of diseases in animal models.\n <\/p>\n

\nThe HIV vector his group developed has also become a standard tool in stem cell research, used to convert fibroblast and other cells to create induced pluripotent (iPS) stem cells (adult cells that have been reprogrammed into a stem cell-like state) and to make experimental model systems for research. Most recently, Verma and his Salk colleague Juan Carlos Izpis\u00faa Belmonte received $6.6 million from the California Institute of Regenerative Medicine to collaborate on treatments that combine gene therapy and stem cell therapy for Fanconi anemia and SCID, both of which are diseases of the blood that are caused by mutation in a single gene.<\/p>\n

\nAbout Inder Verma<\/strong>
\nVerma received a master’s degree from Lucknow University in Uttar Pradesh, India, and his doctorate from The Weizmann Institute of Science in Rehovoth, Israel. After postdoctoral study at MIT in the laboratory of the Nobel laureate David Baltimore, he joined the faculty of the Salk Institute in 1974, at age 26. For his many outstanding accomplishments, Dr. Verma was elected to the U.S. National Academy of Sciences and as a Foreign Fellow to the National Academy of Sciences, India. Verma was also elected to the Third World Academy of Sciences, the Institute of Medicine, the American Academy of Arts and Sciences, and the American Philosophical Society.\n <\/p>\n

\nVerma was the ASGT’s fourth president and founded the society’s journal, Molecular Therapy, serving as its founding editor-in-chief for five years.<\/p>\n

\nAbout the American Society of Gene Therapy<\/strong>
\nThe American Society of Gene Therapy is a nonprofit medical and professional organization that represents researchers and scientists devoted to the discovery of new gene therapies. ASGT was established in 1996 by a group of the country’s leading researchers in gene therapy. With more than 2,000 members worldwide, ASGT is the largest association of individuals involved in gene therapeutics.\n <\/p>\n

\nAcerca del Instituto Salk de Estudios Biol\u00f3gicos:<\/strong>
\nEl Instituto Salk de Estudios Biol\u00f3gicos es una de las instituciones de investigaci\u00f3n b\u00e1sica m\u00e1s destacadas del mundo, donde un cuerpo docente de prestigio internacional investiga cuestiones fundamentales de las ciencias de la vida en un entorno \u00fanico, colaborativo y creativo. Centrados tanto en el descubrimiento como en la formaci\u00f3n de las futuras generaciones de investigadores, los cient\u00edficos del Salk realizan contribuciones revolucionarias a nuestra comprensi\u00f3n del c\u00e1ncer, el envejecimiento, el Alzheimer, la diabetes y las enfermedades cardiovasculares mediante el estudio de la neurociencia, la gen\u00e9tica, la biolog\u00eda celular y vegetal, y otras disciplinas relacionadas.\n <\/p>\n

\nLos logros del cuerpo docente han sido reconocidos con numerosos galardones, entre los que se incluyen premios Nobel y la pertenencia a la Academia Nacional de Ciencias. Fundado en 1960 por el Dr. Jonas Salk, pionero en la vacuna contra la poliomielitis, el Instituto es una organizaci\u00f3n independiente sin fines de lucro y un hito arquitect\u00f3nico. <\/p>","protected":false},"featured_media":0,"template":"","faculty":[115],"disease-research":[],"class_list":["post-1976","disclosure","type-disclosure","status-publish","hentry","faculty-inder-verma"],"acf":[],"yoast_head":"\nSalk Scientist Inder Verma to Receive 2009 Outstanding Achievement Award from American Society of Gene Therapy - Salk Institute for Biological Studies<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.salk.edu\/es\/news-release\/salk-scientist-inder-verma-to-receive-2009-outstanding-achievement-award-from-american-society-of-gene-therapy\/\" \/>\n<meta property=\"og:locale\" content=\"es_MX\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Salk Scientist Inder Verma to Receive 2009 Outstanding Achievement Award from American Society of Gene Therapy - Salk Institute for Biological Studies\" \/>\n<meta property=\"og:description\" content=\"La Jolla, CA\u2014Salk Professor Inder M. 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