{"id":15366,"date":"2017-11-09T11:25:12","date_gmt":"2017-11-09T19:25:12","guid":{"rendered":"https:\/\/vermont.salk.edu\/?post_type=disclosure&#038;p=15366"},"modified":"2018-10-03T14:37:51","modified_gmt":"2018-10-03T21:37:51","slug":"fruit-fly-brains-inform-search-engines-future","status":"publish","type":"disclosure","link":"https:\/\/www.salk.edu\/es\/news-release\/fruit-fly-brains-inform-search-engines-future\/","title":{"rendered":"Fruit fly brains inform search engines of the future"},"content":{"rendered":"<p>LA JOLLA\u2014Every day, websites you visit and smartphone apps that you use are crunching huge sets of data to find things that resemble each other: products that are similar to your past purchases; songs that are similar to tunes you\u2019ve liked; faces that are similar to people you\u2019ve identified in photos. All these tasks are known as similarity searches, and the ability to perform these massive matching games well\u2014and fast\u2014has been an ongoing challenge for computer scientists. <\/p>\n<figure id=\"attachment_15166\"  class=\"wp-caption alignright\"><img decoding=\"async\" class=\"img-responsive wp-image-15166 size-col-md-5\" src=\"https:\/\/www.salk.edu\/wp-content\/uploads\/2017\/11\/Saket-Navlakha_Sanjoy-Dasgupta_Chuck-Stevens_e_MG_0924-458x305.jpeg\" alt=\"From left: Saket Navlakha, Sanjoy Dasgupta, Charles Stevens\" \/><figcaption class=\"wp-caption-text\">From left: Saket Navlakha, Sanjoy Dasgupta, Charles Stevens<\/p>\n<p> <a href=\"https:\/\/www.salk.edu\/wp-content\/uploads\/2017\/11\/Saket-Navlakha_Sanjoy-Dasgupta_Chuck-Stevens_e_MG_0924.jpeg\">Click here<\/a> for a high-resolution image<\/p>\n<p> Credit: Salk Institute<\/figcaption><\/figure>\n<p>Now, Salk and UC San Diego scientists have discovered that the fruit fly brain has an elegant and efficient method of performing similarity searches. For flies, it helps them identify odors that are most similar to those they\u2019ve encountered before, so they know how to behave in response to the odor, such as to approach or avoid it. New details on the fly\u2019s computational approach to smelly similarity searches, described in the journal <em>Science<\/em> on November 9, 2017, could inform computer algorithms of the future. <\/p>\n<p>\u201cThis is a problem that pretty much every technology company with any kind of information retrieval system has to solve, so it\u2019s been something that computer scientists have studied for years,\u201d says <a href=\"https:\/\/www.salk.edu\/scientist\/saket-navlakha\/\">Saket Navlakha<\/a>, assistant professor in Salk\u2019s Integrative Biology Laboratory and lead author of the new paper. \u201cNow, we have this new approach to similarity searches thanks to the fly.\u201d<\/p>\n<p>The way most computerized data systems categorize items\u2015from songs to images\u2015to optimize similarity searches is by reducing the amount of information associated with each item. These systems assign short \u201chashes\u201d to each item so that similar items are more likely to be assigned the same or a similar hash compared to two very different items. (Hashes are a kind of digital shorthand, the way a bitly is a shorter version of a URL.) Assigning hashes in this way is called \u201clocality-sensitive hashing\u201d to computer scientists. When searching for similar items, a program looks through the hashes, rather than the original items, to find similarities quickly.<\/p>\n<div class=\"row\" style=\"\"><div class=\"col-md-10 col-md-push-1\"><div class=\"video-anchor\" id=\"video-PEUMP4UTqrk\"><\/div><div class=\"embed-responsive embed-responsive-16by9\"> <iframe class=\"embed-responsive-item\" src=\"\/\/www.youtube.com\/embed\/PEUMP4UTqrk?rel=0\" webkitallowfullscreen mozallowfullscreen allowfullscreen><\/iframe><\/div><!-- .embed-responsive --><\/div><!-- .col-md-*size --><\/div><!-- .\/row -->\n<p>Navlakha was chatting with colleague <a href=\"https:\/\/www.salk.edu\/scientist\/charles-f-stevens\/\">Charles Stevens<\/a>, a professor in Salk\u2019s Molecular Neurobiology Laboratory and a coauthor of the new work, who had studied fly olfaction, when the former realized that flies\u2014and all animals\u2014are constantly faced with similarity searches as well. So he started combing the literature on the brain circuitry behind fly olfaction to work out just how flies identify similar smells. <\/p>\n<p>\u201cIn the natural world, you\u2019re not going to encounter exactly the same odor every time; there\u2019s going to be some noise and fluctuation,\u201d Navlakha explains. \u201cBut if you smell something that you\u2019ve previously associated with a behavior, you need to be able to identify that similarity and recall that behavior.\u201d So if a fruit fly knows that the smell of a rotting banana means mealtime, it needs to respond the same way when it encounters a very similar smell, even if it never experienced that exact smell before. <\/p>\n<figure id=\"attachment_15166\"  class=\"wp-caption alignleft\"><img decoding=\"async\" class=\"img-responsive wp-image-15166 size-col-md-5\" src=\"https:\/\/www.salk.edu\/wp-content\/uploads\/2017\/11\/Salk-Navlakha-illustration-fly-search-458x424.jpg\" alt=\"\" \/><figcaption class=\"wp-caption-text\">This illustration represents a fruit fly executing a similarity search algorithm based on odor.<\/p>\n<p> <a href=\"https:\/\/www.salk.edu\/wp-content\/uploads\/2017\/11\/Salk-Navlakha-illustration-fly-search.jpg\">Click here<\/a> for a high-resolution image<\/p>\n<p> Credit: Salk Institute<\/figcaption><\/figure>\n<p>Navlakha and his collaborators\u2019 review of the literature revealed that when fruit flies first sense an odor, 50 neurons fire in a combination that\u2019s unique to that smell. But rather than hashing that information by reducing the number of hashes associated with the odor, as computer programs would, flies do the opposite\u2014they expand the dimension. The 50 initial neurons lead to 2,000 neurons, spreading out the input so that each smell has an even more distinct fingerprint among those 2,000 neurons. The brain then stores only the 5 percent of those 2,000 neurons with the top activity as the \u201chash\u201d for that odor. The whole paradigm helps the brain notice similarities better than it would compared to reducing the dimension, Navlakha says. <\/p>\n<p>\u201cSay you have a bunch of people clustered by their relationships, and they\u2019re bunched into a crowded room,\u201d he explains. \u201cThen take the same people and relationships, but have them spread out on a football field. It will be much easier to see the structure of relationships and draw boundaries between groups in the expanded space relative to the crowded space.\u201d<\/p>\n<p>While Navlakha and his collaborators did not reveal the actual mechanism by which flies are storing odor information\u2014that was already available in the literature\u2014they are the first to analyze how this process maximizes speed and efficiency for similarity searches. When they applied the process to three standard datasets computer scientists use to test search algorithms, they found that the fly approach improved performance. This approach, they think, may inform computer programs someday. <\/p>\n<p>\u201cPieces of this approach had been used in the past by computer scientists, but evolution put it together in a very unique way,\u201d says Navlakha. <\/p>\n<p>Navlakha\u2019s collaborators say that the study is among the first to make such concrete parallels between neural circuits in the brain and information processing algorithms used in computer science. <\/p>\n<p>\u201cFor the past 20 years I\u2019ve been interested in random projections [a core component of locality-sensitive hashing for similarity search] as they apply to algorithms running on computers,\u201d says Sanjoy Dasgupta, a professor of computer science and engineering at UCSD and first author of the new paper. \u201cIt never occurred to me that similar operations may be at work in nature.\u201d<\/p>\n<p>\u201cA dream shared by neurobiologists and computer scientists is to understand how the brain computes well enough that we can adapt its methods to improve machine computation,\u201d adds Stevens. \u201cOur paper provides a proof of principle that this dream may become reality.\u201d<\/p>\n<p>The work and the researchers involved were supported by grants from the National Science Foundation (EAGER PHY-1444273) and the Army Research Office (DOD W911NF-17-1-0045).<\/p>\n","protected":false},"featured_media":0,"template":"","faculty":[67,101],"disease-research":[332,146,124],"class_list":["post-15366","disclosure","type-disclosure","status-publish","hentry","faculty-charles-f-stevens","faculty-saket-navlakha","disease-research-computational-biology","disease-research-aging-and-regenerative-medicine","disease-research-neuroscience-and-neurological-disorders"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Fruit fly brains inform search engines of the future - Salk Institute for Biological Studies<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.salk.edu\/es\/news-release\/fruit-fly-brains-inform-search-engines-future\/\" \/>\n<meta property=\"og:locale\" content=\"es_MX\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Fruit fly brains inform search engines of the future - Salk Institute for Biological Studies\" \/>\n<meta property=\"og:description\" content=\"LA JOLLA\u2014Every day, websites you visit and smartphone apps that you use are crunching huge sets of data to find things that resemble each other: products that are similar to your past purchases; songs that are similar to tunes you\u2019ve liked; faces that are similar to people you\u2019ve identified in photos. 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