{"id":14358,"date":"2017-08-01T12:55:43","date_gmt":"2017-08-01T19:55:43","guid":{"rendered":"https:\/\/vermont.salk.edu\/?post_type=disclosure&p=14358"},"modified":"2017-08-03T13:37:06","modified_gmt":"2017-08-03T20:37:06","slug":"salk-lab-part-new-effort-advance-understanding-brain-structure","status":"publish","type":"disclosure","link":"https:\/\/www.salk.edu\/es\/news-release\/salk-lab-part-new-effort-advance-understanding-brain-structure\/","title":{"rendered":"Equipos de Salk forman parte de un nuevo esfuerzo para avanzar en la comprensi\u00f3n de la estructura cerebral"},"content":{"rendered":"

LA JOLLA\u2014Dos laboratorios de neurociencia del Salk forman parte de un esfuerzo de la National Science Foundation (NSF) para comprender mejor el cerebro. Los profesores del Salk Terrence Sejnowski<\/a> y Ed Callaway<\/a> reciben cada uno de los colaboradores en proyectos interinstitucionales m\u00e1s de $9 millones cada uno.<\/p>\n

Los premios se otorgan a trav\u00e9s de la Iniciativa BRAIN<\/a> (a trav\u00e9s de la NSF Redes de Pr\u00f3xima Generaci\u00f3n para Neurociencia, NeuroNex<\/a> como parte de un objetivo mayor para establecer una infraestructura nacional que mejore la comprensi\u00f3n de la funci\u00f3n cerebral a trav\u00e9s de niveles organizacionales y una diversidad de especies. Desde su inicio, la iniciativa BRAIN se ha centrado en nuevas tecnolog\u00edas para descubrir la funci\u00f3n cerebral. Los premios NeuroNex impulsan esa misi\u00f3n al proporcionar a los equipos cient\u00edficos el apoyo que se requiere no solo para continuar superando los l\u00edmites, sino tambi\u00e9n para compartir sus tecnolog\u00edas con otros neurocient\u00edficos a trav\u00e9s de talleres y cursos pr\u00e1cticos.<\/p>\n

\"Terrence
Terrence Sejnowski<\/p>\n

Haga clic aqu\u00ed<\/a> para obtener una imagen en alta resoluci\u00f3n.<\/p>\n

Cr\u00e9dito: Instituto Salk<\/figcaption><\/figure>\n

Sejnowski, la Universidad de Texas en Austin y el Texas Advanced Computing Center (TACC) han recibido una subvenci\u00f3n de m\u00e1s de $9 millones de d\u00f3lares de la National Science Foundation (NSF) para desentra\u00f1ar detalles del cerebro, en particular mediante el mapeo de conexiones llamadas sinapsis. Liderado por UT Austin, el proyecto modelar\u00e1 la funci\u00f3n sin\u00e1ptica y compartir\u00e1 los datos p\u00fablicamente para su uso por parte de cient\u00edficos de todo el mundo.<\/p>\n

\u201cNuestro equipo en el Instituto Salk construir\u00e1 un microscopio computacional para animar los datos del microscopio electr\u00f3nico del proyecto NeuroNex y explorar la funci\u00f3n de las sinapsis a nivel molecular\u201d, dice Sejnowski, jefe de laboratorio del Laboratorio de Neurobiolog\u00eda Computacional de Salk e investigador del Howard Hughes Medical Institute. El equipo crear\u00e1 un nuevo microscopio electr\u00f3nico que pueda obtener im\u00e1genes de vol\u00famenes m\u00e1s grandes de materia cerebral mientras observa simult\u00e1neamente la subestructura m\u00e1s peque\u00f1a de sinapsis individuales. El equipo tambi\u00e9n desarrollar\u00e1 nuevas herramientas de modelado computacional para comprender c\u00f3mo la ultraestructura sin\u00e1ptica apoya la funci\u00f3n cerebral.<\/p>\n

Callaway y un grupo de la Universidad de Stanford tambi\u00e9n han recibido m\u00e1s de $9 millones a trav\u00e9s de las becas NeuroNex. El equipo fusionar\u00e1 principios de gen\u00e9tica, f\u00edsica, \u00f3ptica, ingenier\u00eda y biolog\u00eda para construir y difundir metodolog\u00edas, instrumentaci\u00f3n y an\u00e1lisis que permitan la focalizaci\u00f3n y el control de tipos individuales de c\u00e9lulas cerebrales. El resultado ser\u00e1 una plataforma ampliamente aplicable para descubrir c\u00f3mo la actividad de los circuitos neuronales da lugar a cogniciones y comportamientos complejos en el cerebro, lo que conducir\u00e1 a una mejor comprensi\u00f3n de las enfermedades neurol\u00f3gicas y psiqui\u00e1tricas.<\/p>\n

\"Ed
Ed Callaway<\/p>\n

Haz clic aqu\u00ed para ver una imagen de alta resoluci\u00f3n. <\/p>\n

Cr\u00e9dito: Instituto Salk<\/figcaption><\/figure>\n

Este \u201cequipo de ensue\u00f1o\u201d de investigadores son l\u00edderes en cada uno de los enfoques gen\u00e9ticos clave que se est\u00e1n utilizando para revertir la ingenier\u00eda del cerebro: Callaway, por vincular tipos de c\u00e9lulas a circuitos neuronales; Liqun Luo, por dirigir la expresi\u00f3n g\u00e9nica a tipos espec\u00edficos de c\u00e9lulas cerebrales; Mark Schnitzer, por monitorear la actividad a trav\u00e9s de tecnolog\u00edas de imagen; y el investigador principal del premio, Karl Deisseroth, por la manipulaci\u00f3n optogen\u00e9tica de la actividad neuronal.<\/p>\n

\u201cEstamos entusiasmados con la oportunidad que nos brinda esta financiaci\u00f3n para trabajar estrechamente juntos en llevar nuestras tecnolog\u00edas al siguiente nivel y compartir lo que hemos aprendido con la comunidad\u201d, dice Callaway, quien ostenta la C\u00e1tedra Audrey Geisel en Ciencias Biom\u00e9dicas.<\/p>\n

Los 17 premios NeuroNex anunciados este a\u00f1o re\u00fanen a investigadores de diversas disciplinas con nuevas tecnolog\u00edas y enfoques, dando lugar a maneras novedosas de abordar los misterios del cerebro. Estos proyectos apoyar\u00e1n el desarrollo de capacidades y recursos innovadores, accesibles y compartidos, as\u00ed como marcos te\u00f3ricos y modelado computacional para hacer avanzar la investigaci\u00f3n en neurociencia.<\/p>\n

\u201cA trav\u00e9s del desarrollo de instrumentaci\u00f3n avanzada para observar y modelar el cerebro, estamos m\u00e1s cerca de nuestro objetivo de construir una base de conocimiento m\u00e1s completa sobre c\u00f3mo la actividad neuronal produce el comportamiento\u201d, dice Jim Olds, subdirector de Ciencias Biol\u00f3gicas de la National Science Foundation. \u201cNeuroNex busca impulsar ese progreso, creando un ecosistema de nuevas herramientas, recursos y teor\u00edas. Lo m\u00e1s importante es que NeuroNex tiene como objetivo garantizar su amplia difusi\u00f3n a la comunidad de neurocient\u00edficos. Con estas subvenciones, la NSF est\u00e1 sentando las bases para la pr\u00f3xima generaci\u00f3n de investigaci\u00f3n sobre el cerebro\u201d.\u201d<\/p>","protected":false},"featured_media":0,"template":"","faculty":[84,114],"disease-research":[124],"class_list":["post-14358","disclosure","type-disclosure","status-publish","hentry","faculty-edward-callaway","faculty-terrence-sejnowski","disease-research-neuroscience-and-neurological-disorders"],"acf":[],"yoast_head":"\nSalk teams part of new effort to advance understanding of brain structure - Salk Institute for Biological Studies<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.salk.edu\/es\/news-release\/salk-lab-part-new-effort-advance-understanding-brain-structure\/\" \/>\n<meta property=\"og:locale\" content=\"es_MX\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Salk teams part of new effort to advance understanding of brain structure - Salk Institute for Biological Studies\" \/>\n<meta property=\"og:description\" content=\"LA JOLLA\u2014Two Salk neuroscience labs are part of a National Science Foundation (NSF) effort to better understand the brain. 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