{"id":348,"date":"2015-09-09T12:01:48","date_gmt":"2015-09-09T19:01:48","guid":{"rendered":"https:\/\/vermont.salk.edu\/?page_id=348"},"modified":"2024-01-30T14:07:39","modified_gmt":"2024-01-30T22:07:39","slug":"immune-system-biology","status":"publish","type":"page","link":"https:\/\/www.salk.edu\/de\/science\/research\/immune-system-biology\/","title":{"rendered":"Immunbiologie"},"content":{"rendered":"

Das menschliche Immunsystem ist eine fein abgestimmte Maschine, die abw\u00e4gt, wann sie eine zellul\u00e4re Armee freisetzt, um Krankheitserreger zu bek\u00e4mpfen, und wann sie diese Armee z\u00fcgelt, um einen Angriff auf den K\u00f6rper selbst zu stoppen. Salk-Wissenschaftler untersuchen, wie der K\u00f6rper dieses Gleichgewicht f\u00fcr eine optimale Gesundheit aufrechterh\u00e4lt.<\/p>","protected":false},"excerpt":{"rendered":"

Das menschliche Immunsystem ist eine fein abgestimmte Maschine, die abw\u00e4gt, wann sie eine zellul\u00e4re Armee freisetzt, um Krankheitserreger zu bek\u00e4mpfen, und wann sie diese Armee z\u00fcgelt, um einen Angriff auf den K\u00f6rper selbst zu stoppen. Salk-Wissenschaftler untersuchen, wie der K\u00f6rper dieses Gleichgewicht f\u00fcr eine optimale Gesundheit aufrechterh\u00e4lt.<\/p>","protected":false},"author":3,"featured_media":45818,"parent":40,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"template-research-overview.php","meta":{"_acf_changed":false,"footnotes":""},"folder":[517],"class_list":["post-348","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"yoast_head":"\nImmunobiology - Salk Institute for Biological Studies<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.salk.edu\/de\/science\/research\/immune-system-biology\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Immunobiology - Salk Institute for Biological Studies\" \/>\n<meta property=\"og:description\" content=\"The human immune system is a finely tuned machine, balancing when to release a cellular army to deal with pathogens, with when to rein in that army, stopping an onslaught from attacking the body itself. 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Allergien entstehen, wenn das Immunsystem durch etwas ausgel\u00f6st wird, das der K\u00f6rper f\u00fcr einen Eindringling h\u00e4lt. Salk-Wissenschaftler decken die molekularen Mechanismen solcher Erkrankungen auf, indem sie auf genetische Fehlentwicklungen abzielen, die dazu f\u00fchren, dass unser Immunsystem sich selbst angreift. Diese Forschung k\u00f6nnte zur Entwicklung neuer Therapien sowohl f\u00fcr das Sommerniesen als auch f\u00fcr schwerere allergische Reaktionen f\u00fchren.<\/p>","image":{"ID":44892,"id":44892,"title":"2020","filename":"2020-1.jpg","filesize":50339,"url":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/2020-1.jpg","link":"https:\/\/www.salk.edu\/de\/science\/research\/immune-system-biology\/2020-2\/","alt":"","author":"3","description":"","caption":"","name":"2020-2","status":"inherit","uploaded_to":348,"date":"2023-12-09 04:08:47","modified":"2023-12-09 04:08:47","menu_order":0,"mime_type":"image\/jpeg","type":"image","subtype":"jpeg","icon":"https:\/\/www.salk.edu\/wp-includes\/images\/media\/default.png","width":400,"height":400,"sizes":{"thumbnail":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/2020-1-150x150.jpg","thumbnail-width":150,"thumbnail-height":150,"medium":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/2020-1-300x300.jpg","medium-width":300,"medium-height":300,"medium_large":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/2020-1.jpg","medium_large-width":400,"medium_large-height":400,"large":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/2020-1.jpg","large-width":400,"large-height":400,"1536x1536":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/2020-1.jpg","1536x1536-width":400,"1536x1536-height":400,"2048x2048":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/2020-1.jpg","2048x2048-width":400,"2048x2048-height":400,"trp-custom-language-flag":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/2020-1.jpg","trp-custom-language-flag-width":12,"trp-custom-language-flag-height":12,"hero":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/2020-1.jpg","hero-width":400,"hero-height":400,"square":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/2020-1.jpg","square-width":400,"square-height":400,"cision-147":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/2020-1-147x147.jpg","cision-147-width":147,"cision-147-height":147,"pr-300":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/2020-1-300x300.jpg","pr-300-width":300,"pr-300-height":300,"col-md-5":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/2020-1.jpg","col-md-5-width":400,"col-md-5-height":400,"col-md-6":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/2020-1.jpg","col-md-6-width":400,"col-md-6-height":400,"col-md-7":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/2020-1.jpg","col-md-7-width":400,"col-md-7-height":400,"col-md-8":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/2020-1.jpg","col-md-8-width":400,"col-md-8-height":400,"grid-767":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/2020-1.jpg","grid-767-width":400,"grid-767-height":400,"col-md-10":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/2020-1.jpg","col-md-10-width":400,"col-md-10-height":400,"gform-image-choice-sm":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/2020-1.jpg","gform-image-choice-sm-width":300,"gform-image-choice-sm-height":300,"gform-image-choice-md":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/2020-1.jpg","gform-image-choice-md-width":400,"gform-image-choice-md-height":400,"gform-image-choice-lg":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/2020-1.jpg","gform-image-choice-lg-width":400,"gform-image-choice-lg-height":400}},"faculty":[206,15215,965]},{"title":"Asthma","content":"<p>In den Vereinigten Staaten leiden fast 25 Millionen Menschen an Asthma. F\u00fcr einige ist Asthma eine leichte Bel\u00e4stigung - nur ein gelegentliches Engegef\u00fchl in der Brust und eine gewisse Schleimbildung in der Nase -, aber f\u00fcr andere k\u00f6nnen diese leichten Symptome zu Kurzatmigkeit, Keuchen, Husten und m\u00f6glicherweise sogar zum Tod f\u00fchren. Salk-Wissenschaftler setzen genetische und molekulare Werkzeuge ein, um Asthma besser zu verstehen und den Patienten in Zukunft neue Pr\u00e4ventions- und Therapiem\u00f6glichkeiten zu bieten.<\/p>","image":{"ID":44923,"id":44923,"title":"Ayres-Microscopy-hr (1)","filename":"Ayres-Microscopy-hr-1.jpg","filesize":282696,"url":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/Ayres-Microscopy-hr-1.jpg","link":"https:\/\/www.salk.edu\/de\/science\/research\/immune-system-biology\/ayres-microscopy-hr-1\/","alt":"","author":"3","description":"","caption":"","name":"ayres-microscopy-hr-1","status":"inherit","uploaded_to":348,"date":"2023-12-09 04:23:05","modified":"2023-12-09 04:23:05","menu_order":0,"mime_type":"image\/jpeg","type":"image","subtype":"jpeg","icon":"https:\/\/www.salk.edu\/wp-includes\/images\/media\/default.png","width":974,"height":974,"sizes":{"thumbnail":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/Ayres-Microscopy-hr-1-150x150.jpg","thumbnail-width":150,"thumbnail-height":150,"medium":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/Ayres-Microscopy-hr-1-300x300.jpg","medium-width":300,"medium-height":300,"medium_large":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/Ayres-Microscopy-hr-1-768x768.jpg","medium_large-width":768,"medium_large-height":768,"large":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/Ayres-Microscopy-hr-1.jpg","large-width":974,"large-height":974,"1536x1536":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/Ayres-Microscopy-hr-1.jpg","1536x1536-width":974,"1536x1536-height":974,"2048x2048":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/Ayres-Microscopy-hr-1.jpg","2048x2048-width":974,"2048x2048-height":974,"trp-custom-language-flag":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/Ayres-Microscopy-hr-1.jpg","trp-custom-language-flag-width":12,"trp-custom-language-flag-height":12,"hero":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/Ayres-Microscopy-hr-1-974x550.jpg","hero-width":974,"hero-height":550,"square":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/Ayres-Microscopy-hr-1-767x767.jpg","square-width":767,"square-height":767,"cision-147":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/Ayres-Microscopy-hr-1-147x147.jpg","cision-147-width":147,"cision-147-height":147,"pr-300":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/Ayres-Microscopy-hr-1-300x300.jpg","pr-300-width":300,"pr-300-height":300,"col-md-5":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/Ayres-Microscopy-hr-1-458x458.jpg","col-md-5-width":458,"col-md-5-height":458,"col-md-6":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/Ayres-Microscopy-hr-1-585x585.jpg","col-md-6-width":585,"col-md-6-height":585,"col-md-7":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/Ayres-Microscopy-hr-1-553x553.jpg","col-md-7-width":553,"col-md-7-height":553,"col-md-8":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/Ayres-Microscopy-hr-1-750x750.jpg","col-md-8-width":750,"col-md-8-height":750,"grid-767":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/Ayres-Microscopy-hr-1-767x767.jpg","grid-767-width":767,"grid-767-height":767,"col-md-10":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/Ayres-Microscopy-hr-1-945x945.jpg","col-md-10-width":945,"col-md-10-height":945,"gform-image-choice-sm":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/Ayres-Microscopy-hr-1.jpg","gform-image-choice-sm-width":300,"gform-image-choice-sm-height":300,"gform-image-choice-md":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/Ayres-Microscopy-hr-1.jpg","gform-image-choice-md-width":400,"gform-image-choice-md-height":400,"gform-image-choice-lg":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/Ayres-Microscopy-hr-1.jpg","gform-image-choice-lg-width":600,"gform-image-choice-lg-height":600}},"faculty":[206,15215,965]},{"title":"HIV","content":"<p>HIV (Humanes Immundefizienz-Virus) ist ein Virus, das das Immunsystem des K\u00f6rpers angreift. Wird HIV nicht behandelt, kann es zu AIDS (erworbenes Immundefizienzsyndrom) f\u00fchren, einem Zustand der Immunschw\u00e4che, bei dem Menschen besonders anf\u00e4llig f\u00fcr Infektionen und andere schwere Krankheiten sind. Salk-Wissenschaftler bestimmen die Struktur von HIV mit nahezu atomarer Aufl\u00f6sung. Ihre mikroskopischen Bilder und Modelle tragen zu unserem Verst\u00e4ndnis der molekularen Merkmale der HIV-Infektion bei und liefern chemische Baupl\u00e4ne f\u00fcr potenziell bessere antivirale Therapien.<\/p>","image":{"ID":44962,"id":44962,"title":"Screenshot 2023-12-08 at 8.32.55\u202fPM","filename":"Screenshot-2023-12-08-at-8.32.55\u202fPM.png","filesize":570772,"url":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/Screenshot-2023-12-08-at-8.32.55\u202fPM.png","link":"https:\/\/www.salk.edu\/de\/science\/research\/immune-system-biology\/screenshot-2023-12-08-at-8-32-55-pm\/","alt":"","author":"3","description":"","caption":"","name":"screenshot-2023-12-08-at-8-32-55-pm","status":"inherit","uploaded_to":348,"date":"2023-12-09 04:33:32","modified":"2023-12-09 04:33:32","menu_order":0,"mime_type":"image\/png","type":"image","subtype":"png","icon":"https:\/\/www.salk.edu\/wp-includes\/images\/media\/default.png","width":560,"height":560,"sizes":{"thumbnail":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/Screenshot-2023-12-08-at-8.32.55\u202fPM-150x150.png","thumbnail-width":150,"thumbnail-height":150,"medium":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/Screenshot-2023-12-08-at-8.32.55\u202fPM-300x300.png","medium-width":300,"medium-height":300,"medium_large":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/Screenshot-2023-12-08-at-8.32.55\u202fPM.png","medium_large-width":560,"medium_large-height":560,"large":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/Screenshot-2023-12-08-at-8.32.55\u202fPM.png","large-width":560,"large-height":560,"1536x1536":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/Screenshot-2023-12-08-at-8.32.55\u202fPM.png","1536x1536-width":560,"1536x1536-height":560,"2048x2048":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/Screenshot-2023-12-08-at-8.32.55\u202fPM.png","2048x2048-width":560,"2048x2048-height":560,"trp-custom-language-flag":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/Screenshot-2023-12-08-at-8.32.55\u202fPM.png","trp-custom-language-flag-width":12,"trp-custom-language-flag-height":12,"hero":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/Screenshot-2023-12-08-at-8.32.55\u202fPM-560x550.png","hero-width":560,"hero-height":550,"square":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/Screenshot-2023-12-08-at-8.32.55\u202fPM.png","square-width":560,"square-height":560,"cision-147":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/Screenshot-2023-12-08-at-8.32.55\u202fPM-147x147.png","cision-147-width":147,"cision-147-height":147,"pr-300":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/Screenshot-2023-12-08-at-8.32.55\u202fPM-300x300.png","pr-300-width":300,"pr-300-height":300,"col-md-5":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/Screenshot-2023-12-08-at-8.32.55\u202fPM-458x458.png","col-md-5-width":458,"col-md-5-height":458,"col-md-6":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/Screenshot-2023-12-08-at-8.32.55\u202fPM.png","col-md-6-width":560,"col-md-6-height":560,"col-md-7":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/Screenshot-2023-12-08-at-8.32.55\u202fPM-553x553.png","col-md-7-width":553,"col-md-7-height":553,"col-md-8":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/Screenshot-2023-12-08-at-8.32.55\u202fPM.png","col-md-8-width":560,"col-md-8-height":560,"grid-767":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/Screenshot-2023-12-08-at-8.32.55\u202fPM.png","grid-767-width":560,"grid-767-height":560,"col-md-10":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/Screenshot-2023-12-08-at-8.32.55\u202fPM.png","col-md-10-width":560,"col-md-10-height":560,"gform-image-choice-sm":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/Screenshot-2023-12-08-at-8.32.55\u202fPM.png","gform-image-choice-sm-width":300,"gform-image-choice-sm-height":300,"gform-image-choice-md":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/Screenshot-2023-12-08-at-8.32.55\u202fPM.png","gform-image-choice-md-width":400,"gform-image-choice-md-height":400,"gform-image-choice-lg":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/Screenshot-2023-12-08-at-8.32.55\u202fPM.png","gform-image-choice-lg-width":560,"gform-image-choice-lg-height":560}},"faculty":[6049]},{"title":"Infektionskrankheit","content":"<p>Wenn Eindringlinge wie Bakterien, Viren und Pilze in den K\u00f6rper gelangen, k\u00f6nnen sie Infektionen verursachen, die die Aufmerksamkeit unseres Immunsystems erfordern. Eine breite Kategorie von Krankheiten, die von der Grippe der Atemwege \u00fcber Masern bis hin zu HIV reicht, bietet ein weites Feld f\u00fcr wissenschaftliche Entdeckungen. Die Salk-Forscher versuchen, die Eindringlinge zu verstehen und eine Allianz mit ihnen einzugehen. <\/p>\n<p>Mithilfe neuartiger Bildgebungs- und Entschl\u00fcsselungstechniken k\u00f6nnen wir aus den Strukturen der Eindringlinge und den Methoden ihrer Angriffe lernen, wie unser K\u00f6rper auf Gefahren reagiert - und wie wir diese besser gestalten k\u00f6nnen.<\/p>","image":{"ID":44924,"id":44924,"title":"20230824_E10-Pl8-Pan3-ROI1-Thy11AF488-Ly51PE-B220BV421-THAF647-20x-3x3-Tile-Scan_Stitch_2023-08-17T12-39-44 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Entz\u00fcndung ist die nat\u00fcrliche Reaktion des K\u00f6rpers auf eine Verletzung oder Infektion. Es handelt sich um eine Schutzreaktion, bei der unsere Immunzellen, Blutgef\u00e4\u00dfe und Signalmolek\u00fcle zusammenarbeiten, um die Quelle der Reizung zu beseitigen. Eine \u00dcberaktivierung kann jedoch zu chronischen Entz\u00fcndungen f\u00fchren, die mit Schmerzen, \u00fcberm\u00e4\u00dfigen Schwellungen und sogar Funktionsverlusten einhergehen k\u00f6nnen. Chronische Entz\u00fcndungen werden mit einer Vielzahl von Krankheiten in Verbindung gebracht, darunter Herz-Kreislauf-Erkrankungen, Krebs, Diabetes sowie Autoimmun- und neurodegenerative St\u00f6rungen. In Salk erforschen wir die Rolle, die Proteine und andere Signalmolek\u00fcle bei der Entstehung von Entz\u00fcndungsreaktionen spielen, was zur Entwicklung neuer entz\u00fcndungshemmender Behandlungen f\u00fchren k\u00f6nnte.<\/p>","image":{"ID":44954,"id":44954,"title":"Screenshot 2023-12-08 at 8.30.09\u202fPM","filename":"Screenshot-2023-12-08-at-8.30.09\u202fPM.png","filesize":192311,"url":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/12\/Screenshot-2023-12-08-at-8.30.09\u202fPM.png","link":"https:\/\/www.salk.edu\/de\/science\/research\/immune-system-biology\/screenshot-2023-12-08-at-8-30-09-pm\/","alt":"","author":"3","description":"","caption":"","name":"screenshot-2023-12-08-at-8-30-09-pm","status":"inherit","uploaded_to":348,"date":"2023-12-09 04:30:38","modified":"2023-12-09 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