{"id":26218,"date":"2020-04-14T10:37:13","date_gmt":"2020-04-14T17:37:13","guid":{"rendered":"https:\/\/vermont.salk.edu\/?post_type=disclosure&p=26218"},"modified":"2020-04-14T10:58:43","modified_gmt":"2020-04-14T17:58:43","slug":"salk-scientist-ronald-evans-receives-a-2020-nomis-distinguished-scientist-award","status":"publish","type":"disclosure","link":"https:\/\/www.salk.edu\/de\/news-release\/salk-scientist-ronald-evans-receives-a-2020-nomis-distinguished-scientist-award\/","title":{"rendered":"Salk scientist Ronald Evans receives a 2020 NOMIS Distinguished Scientist Award"},"content":{"rendered":"

LA JOLLA\u2014Salk Professor Ronald Evans<\/a>, Howard Hughes Medical investigator\u00a0and director of Salk\u2019s Gene Expression Laboratory, has been awarded a 2020 NOMIS Distinguished Scientist and Scholar Award by the NOMIS Foundation, a\u00a0Swiss foundation that supports high-risk basic research. The award, which totals $2.5M, recognizes scientists for their \u201coutstanding contributions to the advancement of science and human progress through their pioneering, innovative and collaborative research,\u201d according to NOMIS. The award will enable Evans to decode how different parts of the body, including the brain, endocrine glands, gut, liver, immune cells and the microbiome, cooperate to maintain health.<\/p>\n

\"Ronald
Ronald Evans<\/p>\n

Klicken Sie hier<\/a> f\u00fcr ein hochaufl\u00f6sendes Bild.<\/p>\n

Kredit: Salk Institut<\/figcaption><\/figure>\n

Evans is a member of Salk’s\u00a0NOMIS Center for Immunobiology and Microbial Pathogenesis, which was launched in 2008 as part of what is today a longstanding alliance with the NOMIS Foundation.\u00a0The center aims to shed light on the molecular mechanisms that cause infectious diseases, define key molecules involved in the body\u2019s response to injury and infection, elucidate the rules of engagement between the body\u2019s microbiome and immune system, and understand why inflammatory processes spin out of control under some circumstances.\u00a0Salk trustee Markus Reinhard is managing director of the NOMIS Foundation.<\/p>\n

\u201cWe are grateful to NOMIS for recognizing Ron\u2019s contributions to science as well as for supporting his interdisciplinary approach to better understanding how\u00a0organs communicate with one another,\u201d says Salk President Rusty Gage. \u201cRon’s\u00a0Science of Health project could lead to new preventative strategies for diabetes, cancer and neurodegenerative disorders\u00a0such as Alzheimer\u2019s.\u00a0We are very proud to have Ron as a member of NOMIS\u00a0for the Salk community.\u201d<\/p>\n

Evans is known for revolutionizing the fields of endocrinology and metabolism, and for producing novel classes of drugs that act on genes. He discovered a \u201csuperfamily\u201d of 48 genes called nuclear hormone receptors (NRs), that respond to steroid and thyroid hormones, vitamins A and D, as well as to dietary fats and bile acids. This led to the unifying theory of hormone action in which gene networks control body physiology from embryonic development to adulthood. Evans identified novel NRs involved in inflammation, cancer, diabetes and the creation of new brain cells (neurogenesis).<\/p>\n

He also first identified exercise mimetics, molecules sometimes collectively called \u201cexercise in a pill.\u201d By acting on \u00a0mitochondria, the power houses of the cell, exercise mimetics confer the benefits of fitness without training. And by improving physical endurance, they also lower inflammation, promote weight loss, lower blood sugar and enhance memory.<\/p>\n

The NOMIS-funded project, called \u201cThe Science of Health: A New Perspective for Treating Disease,\u201d seeks to understand organ communication by exploring the use of exercise mimetics to prevent neurodegenerative diseases. It will also examine the interplay between immune responses and the gut microbiome; the protective effects of vitamin D against liver damage; and how stimulating NRs \u201clocally\u201d in the gut acts \u201cglobally\u201d on the liver and pancreas to manage diabetes and metabolic disease.<\/p>\n

Evans earned his BA in bacteriology and PhD in microbiology and immunology from the University of California, Los Angeles, and completed his postdoctoral fellowship at Rockefeller University. He has received numerous accolades, including the Wolf Prize in Medicine, the Albany Medical Center Prize in Medicine and Biomedical Research, the Canada Gairdner Foundation International Award, the Albert Lasker Award for Basic Medical Research, the March of Dimes Prize and the Keio Medical Science Prize. He is a member of the National Academy of Sciences and the National Academy of Medicine, and holds the March of Dimes Chair in Molecular and Developmental Biology at Salk.<\/p>\n

About NOMIS: <\/strong><\/p>\n

NOMIS supports and enables insight-driven science across all disciplines, focusing on researchers who put forth bold new ideas, exhibit a pioneering spirit and seek to inspire the world around them. Their vision is to \u201ccreate a spark\u201d in the world of science by enabling pioneering research in the natural sciences, social sciences and the humanities that benefits humankind and our planet.<\/p>\n

\u00dcber das Salk Institute for Biological Studies:<\/strong><\/p>\n

Every cure has a starting point. The Salk Institute embodies Jonas Salk\u2019s mission to dare to make dreams into reality. Its internationally renowned and award-winning scientists explore the very foundations of life, seeking new understandings in neuroscience, genetics, immunology, plant biology and more. The Institute is an independent nonprofit organization and architectural landmark: small by choice, intimate by nature and fearless in the face of any challenge. Be it cancer or Alzheimer\u2019s, aging or diabetes, Salk is where cures begin. Learn more at: salk.edu.<\/p>","protected":false},"featured_media":26220,"template":"","faculty":[91],"disease-research":[279],"class_list":["post-26218","disclosure","type-disclosure","status-publish","has-post-thumbnail","hentry","faculty-ronald-evans","disease-research-awards"],"acf":[],"yoast_head":"\nSalk scientist Ronald Evans receives a 2020 NOMIS Distinguished Scientist Award - Salk Institute for Biological Studies<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.salk.edu\/de\/news-release\/salk-scientist-ronald-evans-receives-a-2020-nomis-distinguished-scientist-award\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Salk scientist Ronald Evans receives a 2020 NOMIS Distinguished Scientist Award - Salk Institute for Biological Studies\" \/>\n<meta property=\"og:description\" content=\"LA JOLLA\u2014Salk Professor Ronald Evans, Howard Hughes Medical investigator\u00a0and director of Salk\u2019s Gene Expression Laboratory, has been awarded a 2020 NOMIS Distinguished Scientist and Scholar Award by the NOMIS Foundation, a\u00a0Swiss foundation that supports high-risk basic research. 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