{"id":2452,"date":"2013-09-27T00:00:00","date_gmt":"2013-09-27T07:00:00","guid":{"rendered":"https:\/\/vermont.salk.edu\/news-release\/promising-new-research-earns-salk-scientist-career-development-award\/"},"modified":"2013-09-27T00:00:00","modified_gmt":"2013-09-27T07:00:00","slug":"promising-new-research-earns-salk-scientist-career-development-award","status":"publish","type":"disclosure","link":"https:\/\/www.salk.edu\/de\/news-release\/promising-new-research-earns-salk-scientist-career-development-award\/","title":{"rendered":"Promising new research earns Salk scientist Career Development Award"},"content":{"rendered":"<p>LA JOLLA, CA\u2014The <a href=\"http:\/\/jdrf.org\/\">Juvenile Diabetes Research Foundation (JDRF)<\/a> has given Salk scientist <a href=\"\/de\/faculty\/huising.html\/\">Mark Huising<\/a> a five-year, $750,000 Career Development Award for his proposed study on how a novel network of receptors in human islets receives and integrates molecular signals. In pre-clinical models, activation of these receptors has proven to actually prevent diabetes. Career Development Awards are highly competitive and bestowed upon only a handful of people each year.\n<\/p>\n<p>\nThe goal of Huising&#8217;s study, entitled &#8220;Urocortin 3 Marks Mature Beta Cells and Prevents Diabetes,&#8221; is to understand how this protection against diabetes is accomplished. &#8220;Despite years of research,&#8221; he says, &#8220;significant gaps remain in our understanding of the way the islet receives and integrates signals from a wide variety of sources. We envision that among these networks of signaling molecules remain plenty that are unknown and can lead to novel strategies to treat or cure Type 1 diabetes.&#8221;\n<\/p>\n<p>\nType 1 diabetes is a chronic condition in which the pancreas produces little or no insulin. Although the condition, which usually appears during childhood or adolescence, can be managed, it&#8217;s a daily juggling act. Food, exercise and insulin must be carefully balanced with scheduled blood sugar checks and insulin injections. A diagnosis of diabetes is also a major risk factor for such later complications as cardiac failure, kidney problems and lower limb amputations. To date, Type 1 diabetes has no cure, making Huising&#8217;s research all the more exciting. <\/p>\n<p>\nHuising received his doctorate in biology at Radboud University Nijmegen, the Netherlands. Currently working in the <a href=\"\/de\/faculty\/clayton_foundation_laboratories_for_peptide_biology.html\/\">Clayton Foundation Laboratorien f\u00fcr Peptidbiologie<\/a> at the Salk Institute, Huising and his team study the actions of corticotropin-releasing factor (CRF) and urocortins in the pancreas. Urocortin 3, a peptide related to CRF, is abundantly expressed by mature beta cells and makes important contributions to the regulation of insulin secretion and glucose metabolism. <\/p>\n<p>\nThe JDRF is the leading global organization funding Type 1 diabetes research. The foundation currently sponsors $530 million in scientific research in 17 countries and emphasizes seeking researchers &#8220;who will bridge the gap between the bench and bedside.&#8221; The primary purpose of the Career Development Award is to &#8220;attract qualified and promising scientists early in their faculty careers and to give them the opportunity to establish themselves&#8221; in areas pertinent to diabetes research.<\/p>\n<p><strong><br \/>\n\u00dcber das Salk Institute for Biological Studies:<\/strong><br \/>Das Salk Institute for Biological Studies ist eine der weltweit f\u00fchrenden Institutionen f\u00fcr Grundlagenforschung, an der international renommierte Fakult\u00e4tsmitglieder grundlegende Fragen der Biowissenschaften in einem einzigartigen, kollaborativen und kreativen Umfeld untersuchen. Mit dem Fokus auf Entdeckungen und die Ausbildung zuk\u00fcnftiger Forschergenerationen leisten Salk-Wissenschaftler bahnbrechende Beitr\u00e4ge zu unserem Verst\u00e4ndnis von Krebs, Alterung, Alzheimer, Diabetes und Infektionskrankheiten durch die Untersuchung von Neurowissenschaften, Genetik, Zell- und Pflanzenbiologie sowie verwandten Disziplinen.<\/p>\n<p>\nDie Leistungen der Fakult\u00e4t wurden mit zahlreichen Auszeichnungen gew\u00fcrdigt, darunter Nobelpreise und Mitgliedschaften in der National Academy of Sciences. Das 1960 vom Polio-Impfstoff-Pionier Dr. Jonas Salk gegr\u00fcndete Institut ist eine unabh\u00e4ngige gemeinn\u00fctzige Organisation und ein architektonisches Wahrzeichen.<\/p>","protected":false},"featured_media":0,"template":"","faculty":[],"disease-research":[173,123,138],"class_list":["post-2452","disclosure","type-disclosure","status-publish","hentry","disease-research-diabetes-type-1","disease-research-metabolism-and-diabetes","disease-research-pre-diabetes"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Promising new research earns Salk scientist Career Development Award - Salk Institute for Biological Studies<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.salk.edu\/de\/news-release\/promising-new-research-earns-salk-scientist-career-development-award\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Promising new research earns Salk scientist Career Development Award - Salk Institute for Biological Studies\" \/>\n<meta property=\"og:description\" content=\"LA JOLLA, CA\u2014The Juvenile Diabetes Research Foundation (JDRF) has given Salk scientist Mark Huising a five-year, $750,000 Career Development Award for his proposed study on how a novel network of receptors in human islets receives and integrates molecular signals. 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