{"id":18409,"date":"2018-06-26T11:50:40","date_gmt":"2018-06-26T18:50:40","guid":{"rendered":"https:\/\/vermont.salk.edu\/?post_type=disclosure&p=18409"},"modified":"2018-06-26T12:06:05","modified_gmt":"2018-06-26T19:06:05","slug":"salk-researchers-win-five-competitive-grants-for-cancer-research","status":"publish","type":"disclosure","link":"https:\/\/www.salk.edu\/de\/news-release\/salk-researchers-win-five-competitive-grants-for-cancer-research\/","title":{"rendered":"Salk researchers win five competitive grants for cancer research"},"content":{"rendered":"

LA JOLLA\u2014Salk Institute scientists Ronald Evans<\/a>, Diana Hargreaves<\/a>, Tony Hunter<\/a>, Graham McVicker<\/a> und Geoffrey Wahl<\/a> are among the first wave of researchers to receive funding from Padres Pedal the Cause, one of one of the largest stand-alone cancer fundraising events in San Diego. The nonprofit raised $2.4 million for cancer research in November 2017, thanks to the efforts of more than 3,000 bicycle riders, sponsors, volunteers and donors.<\/p>\n

\"\"
Padres Pedal the Cause presented a check for $2,401,523.00 to representatives from Moores Cancer Center at UC San Diego Health, Sanford Burnham Prebys Medical Discovery Institute, the Salk Institute for Biological Studies and Rady Children\u2019s Hospital\u2013San Diego. <\/p>\n

From left to right: Bill Koman, Padres Pedal Founder; Geoffrey M. Wahl, Ph.D. \u2013 Salk Institute for Biological Studies; Anne Marchand, Executive Director \u2013 Padres Pedal; Christopher J. Kane, MD \u2013 Moores Cancer Center at UC San Diego Health; Garth Powis, D. Phil. \u2013 Sanford Burnham Prebys Medical Discovery Institute; Donald Kearns, M.D., M.M.M., President & CEO \u2013 Rady Children\u2019s Hospital\u2013San Diego <\/p>\n

Klicken Sie hier<\/a> for a high-resolution image <\/p>\n

Credit: Padres Pedal the Cause<\/figcaption><\/figure>\n

Pedal the Cause awards millions of dollars each year via its Discovery Grants program to cross-institutional teams of physicians and scientists from San Diego\u2019s best cancer institutions, including the Salk Institute for Biological Studies, Moores Cancer Center at UC San Diego Health, Sanford Burnham Prebys Medical Discovery Institute and Rady Children\u2019s Hospital.<\/p>\n

“The Padres Pedal the Cause Discovery Grants are opening the door to critically needed research,” say Professors Geoffrey Wahl of Salk and Frank Furnari of UC San Diego, who are leading a 2018 Discovery Grant together. “This funding has allowed us to build a highly collaborative research team to tackle glioblastoma, a particularly aggressive brain cancer.”<\/p>\n

According to Pedal the Cause, the Discovery Grant funding process is highly selective and proposals are screened via a rigorous vetting process. Funding is awarded to best-in-class project submissions to green-light project exploration with the hope that initial findings may lead to additional funding from national sources and, ultimately, a cure.<\/p>\n

Salk scientists are co\u2013principal investigators on Projects 3, 7, 8, 9 and 10 of the 2018 Discovery Grants listed below:<\/p>\n

Project 1: \u201cInducing Cytosolic Chromatin Fragments in Cancer Cells to Turn Cold Tumors Hot\u201d<\/strong>
\nJack Bui, Moores Cancer Center
\nPeter Adams, Sanford Burnham Prebys Medical Discovery Institute<\/p>\n

Project 2: \u201cUnderstanding and Targeting NRF2 in Pancreatic Cancer\u201d<\/strong>
\nMichael Karin, Moores Cancer Center
\nAndrew Lowy, Moores Cancer Center
\nJorge Moscat, Sanford Burnham Prebys Medical Discovery Institute<\/p>\n

Project 3: \u201cTargeting a Therapeutic Vulnerability in PTEN-Deficient Brain Tumors\u201d<\/strong>
\nFrank Furnari, Moores Cancer Center
\nGeoffrey Wahl<\/a>, Salk Institute for Biological Studies<\/p>\n

Project 4: \u201cNatural Killer Cells for Treatment of Medulloblastoma\u201d<\/strong>
\nDan S. Kaufman, Moores Cancer Center
\nRobert J. Wechsler-Reya, Sanford Burnham Prebys Medical Discovery Institute<\/p>\n

Project 5: \u201cTranscriptomic and Epigenomic Profiling to Reveal Tumor-Infiltrating Lymphocyte and Microglia Functional Phenotype and Clonality In Pediatric Brain Tumors\u201d<\/strong>
\nAnusha Preethi Ganesan, Rady Children\u2019s Hospital, San Diego
\nP. Vijayanand, La Jolla Institute<\/p>\n

Project 6: \u201cResponses of Melanoma Patients to Checkpoint Immunotherapy\u201d<\/strong>
\nLinda Bradley, Sanford Burnham Prebys Medical Discovery Institute
\nGregory Daniels, Moores Cancer Center<\/p>\n

Project 7: \u201cEnhanced Breast Cancer Risk Prediction from Imputed Gene Expression\u201d<\/strong>
\nHannah Carter, Moores Cancer Center
\nGraham McVicker<\/a>, Salk Institute for Biological Studies<\/p>\n

Project 8: \u201cEpigenetic Profiling of Endometrial Cancer\u201d
\nDiana Hargreaves<\/a>, Salk Institute for Biological Studies
\nRamez Eskander, Moores Cancer Center<\/p>\n

Project 9: \u201cTargeting Fibroblast Heterogeneity to Improve Surgical Outcomes in Pancreatic Cancer\u201d<\/strong>
\nRonald M. Evans<\/a>, Salk Institute for Biological Studies
\nMichael Bouvet, Moores Cancer Center<\/p>\n

Project 10: \u201cA Novel Role for Histidine Kinase Activity in Neuroblastoma Pathogenesis\u201d<\/strong>
\nPeter Zage, Rady Children\u2019s Hospital, San Diego
\nTony Hunter<\/a>, Salk Institute for Biological Studies<\/p>\n

Project 11: \u201cDevelopment and Implementation of a Peer-Navigation Intervention to Improve Research Literacy in Pediatric Cancer Trials\u201d<\/strong>
\nPaula Aristizabal, Rady Children\u2019s Hospital, San Diego
\nElena Martinez, UC San Diego Health<\/p>\n

About Padres Pedal the Cause:<\/strong>
\nPadres Pedal the Cause is a 501(c)(3) nonprofit organization dedicated to funding collaborative cancer research in San Diego. To date, Padres Pedal has raised and donated over $7.1 million to fund 42 translational research projects at Moores Cancer Center at UC San Diego Health, the Salk Institute for Biological Studies, Rady Children\u2019s Hospital and Sanford Burnham Prebys Medical Discovery Institute. It is our goal that the research funded by Padres Pedal the Cause will lead to increased survivorship and ultimately, a cure. For more information or to register for the November 17 event, please visit www.gopedal.org<\/a> or on Facebook, Instagram and Twitter. <\/p>","protected":false},"featured_media":0,"template":"","faculty":[74,90,99,91,72],"disease-research":[46],"class_list":["post-18409","disclosure","type-disclosure","status-publish","hentry","faculty-diana-hargreaves","faculty-geoffrey-wahl","faculty-graham-mcvicker","faculty-ronald-evans","faculty-tony-hunter","disease-research-cancer-biology"],"acf":[],"yoast_head":"\nSalk researchers win five competitive grants for cancer research - Salk Institute for Biological Studies<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.salk.edu\/de\/news-release\/salk-researchers-win-five-competitive-grants-for-cancer-research\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Salk researchers win five competitive grants for cancer research - Salk Institute for Biological Studies\" \/>\n<meta property=\"og:description\" content=\"LA JOLLA\u2014Salk Institute scientists Ronald Evans, Diana Hargreaves, Tony Hunter, Graham McVicker and Geoffrey Wahl are among the first wave of researchers to receive funding from Padres Pedal the Cause, one of one of the largest stand-alone cancer fundraising events in San Diego. 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