Geoffrey Wahl, PhD

Professor

Gene Expression Laboratory

Geoffrey Wahl
Salk Institute for Biological Studies - News

News


Salk Institute Professor Geoffrey Wahl receives 2022 Susan G. Komen® Brinker Award

LA JOLLA—Salk Institute Professor Geoffrey Wahl has received the 2022 Brinker Award for Scientific Distinction in Basic Science from Susan G. Komen®, the world’s leading breast cancer organization. According to …


Uncovering how injury to the pancreas impacts cancer formation

Pancreatic acinar cells form a diverse population of new cell types in response to injury with the potential to limit or drive disease. Acinar-derived clones labeled in red and green.Click …

Location, location, location: the cell membrane facilitates RAS protein interactions

LA JOLLA—Many cancer medications fail to effectively target the most commonly mutated cancer genes in humans, called RAS. Now, Salk Professor Geoffrey Wahl and a team of scientists have uncovered …


Mysterious tuft cells found to play role in pancreatitis

LA JOLLA—Persistent inflammation of the pancreas (chronic pancreatitis) is a known risk factor for developing pancreatic cancer, the third-deadliest cancer in the United States. Tuft cells—cells sensitive to chemical (chemosensory) …


Mapping normal breast development to better understand cancer

LA JOLLA—Breast cancer is one of the most prevalent cancers, and some forms rank among the most difficult to treat. Its various types and involvement of many different cells makes …


A master switch controls aggressive breast cancer

LA JOLLA—A team at the Salk Institute has identified a master switch that appears to control the dynamic behavior of tumor cells that makes some aggressive cancers so difficult to …


Back to the future: breast cancer reprises pathways found in fetal cells

Pictured is mammary tissue of a developing mouse embryo at day 18, with cells that express both luminal protein (red) and basal protein (green). Cells in breast cancer often show …

Salk researchers win five competitive grants for cancer research

LA JOLLA—Salk Institute scientists Ronald Evans, Diana Hargreaves, Tony Hunter, Graham McVicker and Geoffrey Wahl are among the first wave of researchers to receive funding from Padres Pedal the Cause, …


Salk Institute launches Conquering Cancer Initiative

LA JOLLA—On Friday, April 20, 2018, the Salk Institute launched a new initiative called Conquering Cancer, to harness specific and emerging scientific strategies to tackle the five deadliest cancers: pancreatic, …


Errant gene turns cells into mobile cancer factories

LA JOLLA–A single stem cell has the potential to generate an animal made of millions of different types of cells. Some cancers contain stem-like but abnormal cells that can act …


Geoffrey Wahl named a National Cancer Institute Outstanding Investigator Award recipient to further his cancer research

LA JOLLA—Salk Professor Geoffrey Wahl will receive the National Cancer Institute (NCI) Outstanding Investigator Award (OIA), which encourages cancer research with breakthrough potential. Wahl, a professor in Salk’s Gene Expression …


Salk scientists unveil powerful method to speed cancer drug discovery

LA JOLLA–For decades, researchers have struggled to translate basic scientific discoveries about cancer into therapeutics that effectively–and with minimal side effects–shrink a tumor.

One avenue that may hold great potential …


Pedal the Cause funds local ground-breaking cancer research with inaugural grant awards

LA JOLLA—Pedal the Cause, the region’s only multiday cycling fundraiser where 100 percent of the net proceeds goes to support cancer research in San Diego, today announced five research projects …


Ability to isolate and grow breast tissue stem cells could speed cancer research

LA JOLLA—By carefully controlling the levels of two proteins, researchers at the Salk Institute have discovered how to keep mammary stem cells—those that can form breast tissue—alive and functioning in …


Geoffrey Wahl elected to Academy of Arts and Sciences class of 2014 for outstanding scientific work

LA JOLLA—The American Academy of Arts and Sciences (AAAS) elected Salk Professor Geoffrey M. Wahl to its society, whose ranks include Nobel laureates, Pulitzer Prize recipients and Oscar winners, as …


American Association for Cancer Research appoints Salk scientists to inaugural class of fellows

LA JOLLA, CA—The American Association for Cancer Research (AACR), the world’s oldest and largest professional organization dedicated to accelerating scientific progress to prevent and cure cancer, has selected four Salk …


Prestigious endowed chairs awarded to Salk scientists

The Salk Institute is pleased to announce that faculty members Geoffrey M. Wahl and Martyn Goulding were celebrated as the recipients of endowed chairs in recognition of their significant scientific …


Salk scientists use an old theory to discover new targets in the fight against breast cancer

LA JOLLA, CA—Reviving a theory first proposed in the late 1800s that the development of organs in the normal embryo and the development of cancers are related, scientists at the …


The genome guardian’s dimmer switch: regulating p53 is a matter of life or death

LA JOLLA, CA—Scientists at the Salk Institute for Biological Studies have found clues to the functioning of an important damage response protein in cells. The protein, p53, can cause cells …


The stemness of cancer cells

LA JOLLA, CA—A close collaboration between researchers at the Salk Institute for Biological Studies and the Institute for Advanced Study found that the tumor suppressor p53, long thought of as …


Tumor suppressor pulls double shift as reprogramming watchdog

LA JOLLA, CA—A collaborative study by researchers at the Salk Institute for Biological Studies uncovered that the tumor suppressor p53, which made its name as “guardian of the genome,” not …


The two faces of Mdmx: Why some tumors don’t respond to radiation and chemotherapy

LA JOLLA, CA—A tightly controlled system of checks and balances ensures that a powerful tumor suppressor called p53 keeps a tight lid on unchecked cell growth but doesn’t wreak havoc …


Salk Institute Scientist Plays Pivotal Role in More Than $100 Mill National “Stand Up To Cancer” Fundraising, Pancreatic Cancer Research “Dream Team”

La Jolla-More than three years ago, while serving as president-elect and then president of the American Association for Cancer Research (AACR), Salk scientist Geoff Wahl had an …


Geoffrey M. Wahl named 2008 AAAS Fellow

Salk researcher Geoffrey M. Wahl, a professor in the Gene Expression Laboratory, has been awarded the distinction of AAAS Fellow, an honor bestowed upon members of the American Association for …


New model of p53 regulation proposed that suggests novel anticancer strategy

La Jolla, CA – Genetically engineered mice convinced scientists at the Salk Institute for Biological Studies that it was time to overhaul widely held beliefs about …


Cancer related gene p53 not regulated as indicated by previous tissue culture research; results may be relevant to drug development

La Jolla, CA – The cellular cascade of molecular signals that instructs cells with fatally damaged DNA to self-destruct pivots on the p53 tumor suppressor gene. If p53 is inactivated, …


Salk Institute scientist Geoff Wahl named President-elect of world’s largest cancer research organization

La Jolla, CA – Geoffrey M. Wahl, Ph.D., professor at the Salk Institute for Biological Studies, recently was elected the 2006-07 president of the American Association for Cancer Research (AACR), …


Elusive chromosomal “ignition” identified by Salk scientists

La Jolla, CA – Before the engine that drives cell division goes into gear, it must receive a biological spark from its genetic machinery to set the process in motion. …


Education

BA, Bacteriology, UCLA
PhD, Biological Chemistry, Harvard University
Postdoctoral Fellow, Stanford University


Awards & Honors

  • Susan G. Komen® Brinker Award, 2022
  • National Cancer Institute (NCI) Outstanding Investigator Award, 2015-Present
  • American Academy of Arts And Sciences (AAAS) Fellow, 2014
  • American Association for Cancer Research Fellow, 2013
  • American Association for the Advancement Of Science (AAAS) Fellow, 2008
  • Scientific Advisory Board, Pancreatic Cancer Action Network, 2007-2014
  • Susan G. Komen Scholar, 2010-Present
  • President, American Association for Cancer Research, 2006-2007
  • “Citation Classic” Designation for One of the Most Highly Cited Scientific Papers, 1961-1982
  • American Men And Women of Science