Alan Saghatelian, PhD

Professor

Clayton Foundation Laboratories for Peptide Biology

Dr. Frederik Paulsen Chair

Salk Institute for Biological Studies - News

News


Microprotein increases appetite in mice

LA JOLLA—Obesity and metabolic diseases, such as diabetes, are extremely common in the United States. Tiny proteins called microproteins have long been overlooked in research, but new evidence demonstrates that …


Salk scientists discover anti-inflammatory molecules that decline in the aging brain

LA JOLLA—Aging involves complicated plot twists and a large cast of characters: inflammation, stress, metabolism changes, and many others. Now, a team of Salk Institute and UC San Diego scientists …


Salk scientists receive 2022 Mark Foundation Endeavor Award to study lung cancer

LA JOLLA—Professors Reuben Shaw, Susan Kaech, Christian Metallo and Alan Saghatelian have received a 2022 Mark Foundation for Cancer Research Endeavor Award to support their research exploring the metabolic changes …


Salk Institute among cross-collaborative teams gifted $220 million by Wu Tsai Human Performance Alliance

LA JOLLA—A Salk Institute team led by Professor Satchin Panda, along with teams from five other organizations, have been awarded a total of $220 million by the Joe and Clara …


Salk Professors Susan Kaech and Alan Saghatelian named 2020 AAAS Fellows

LA JOLLA—Salk Professors Susan Kaech and Alan Saghatelian have been named 2020 Fellows of the American Association for the Advancement of Science (AAAS), the world’s largest general scientific society and …


Salk researchers accelerate, expand COVID-19 research

LA JOLLA—As the COVID-19 pandemic continues across the globe, the Salk Institute joins in efforts to understand the fundamental science behind the novel coronavirus to pave the way to treatments …


Experimental drug boosts levels of “good” fats

LA JOLLA—Salk and Scripps Research Institute scientists, along with collaborators at the pharmaceutical company Lundbeck, identified two genes that can regulate levels of healthy fats, called FAHFAs, in mice. The …


Finding the smallest genes could yield outsized benefits

LA JOLLA—While scientists know of about 25,000 genes that code for biologically important proteins, additional, smaller genes hiding in our DNA may be just as important. But these tiny lines …


Mysterious microproteins have major implications for human disease

LA JOLLA—As the tools to study biology improve, researchers are beginning to uncover details into microproteins, small components that appear to be key to some cellular processes, including those involved …


Depleting microbiome with antibiotics can affect glucose metabolism

LA JOLLA—A new study from the Salk Institute has found that mice that have their microbiomes depleted with antibiotics have decreased levels of glucose in their blood and better insulin …


Salk scientists curb growth of cancer cells by blocking access to key nutrients

LA JOLLA—Salk researchers have discovered how to curb the growth of cancer cells by blocking the cells’ access to certain nutrients. The approach, detailed in a new paper published today …


The right way to repair DNA

Chromosomes (red) with telomeres (green) that are undisturbed remain pristine and separate. Right: when CYREN is absent, chromosomes that have been disturbed to artificially trigger NHEJ show fusions that are …

Small but mighty: tiny proteins with big roles in biology

LA JOLLA—We all know how hard it is to find something small like a dropped contact lens that blends into the background. It’s similarly tough for biologists to find tiny …


New mechanism discovered for Alzheimer’s risk gene

LA JOLLA—For decades, scientists have known that people with two copies of a gene called apolipoprotein E4 (ApoE4) are much more likely to have Alzheimer’s disease at age 65 than …


TSRI, Salk scientists discover ‘outlier’ enzymes that could offer new targets to treat diabetes, inflammation

LA JOLLA—A team led by scientists at The Scripps Research Institute (TSRI) and the Salk Institute for Biological Studies has discovered two enzymes that appear to play a role in …


Scientists discover a ‘good’ fat that fights diabetes

LA JOLLA–Scientists at the Salk Institute and Beth Israel Deaconess Medical Center (BIDMC) in Boston have discovered a new class of molecules–produced in human and mouse fat–that protects against diabetes.

The …


Salk Institute welcomes four new faculty

LA JOLLA—The Salk Institute is pleased to welcome a new full professor and three new assistant professors, all exceptional leaders in their respective fields. The new faculty will facilitate innovative …


Education

BS, Chemistry, University of California, Los Angeles
PhD, Chemistry, The Scripps Research Institute, La Jolla, Ca
Merck Postdoctoral Fellow of the Life Sciences Research Foundation, 2003


Affiliations


Awards & Honors

  • Mark Foundation for Cancer Research Endeavor Award, 2022
  • Fellows of the American Association for the Advancement of Science, 2020
  • Sloan Foundation Fellow, 2011
  • Searle Scholars Program Award, 2008
  • New Innovator Award, National Institutes of Health, 2007
  • Burroughs Wellcome Fund Career Award in Biomedical Sciences, 2005