Hsu aims to develop the next generation of medical therapeutics by harnessing the gene editing technology known as CRISPR. A gene editing technique originally derived from bacterial immune systems, CRISPR has recently made headlines for its use in modifying DNA with unprecedented ease and accuracy. The Hsu lab develops diverse approaches from synthetic biology, genomics, and neuroscience for the high-throughput interrogation and control of transcriptional and epigenetic cell states, particularly for the treatment of neurodegenerative disease and complex genetic disorders.
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After obtaining his undegraduate degree in Chemistry/Biochemistry from UCSD, Dmitry Lyumkis obtained his PhD in Biophysics from the Scripps Research Institute in La Jolla, CA, working under the supervision of Bridget Carragher and Clinton S. Potter. His interests lie in utilizing electron microscopy to gain insight into macromolecular assemblies, while at the same time pushing the technological limits of the single-particle methodology. He is currently a Helmsley-Salk Fellow at the Salk Institute for Biological Studies.
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Helmsley Postdoctoral Fellows
Elena Blanco SuarezMolecular Neurobiology Laboratory (Nicola Allen) ‘Identification of an astrocyte-secreted factor that regulates neuronal synapse formation’
Aaron Yun ChenMolecular and Cell Biology Laboratory (Clodagh O’Shea) ‘Determining the role and genomic regulation of a novel p53 activated immune/inflammation pathway in limiting viral and tumor replication ’
Joanna San PedroMolecular and Cell Biology Laboratory (Clodagh O’Shea) ‘Visualizing the nuclear architecture: Development of a universal method for identifying genomic interactions of insoluble protein complexes ’
Yu ShiMolecular and Cell Biology Laboratory (Tony Hunter) ‘Targeting the pancreatic stellate cells for pancreatic cancer therapy’