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Technology for Oncology Applications

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S00014: Bushman

Method of Rapidly Identifying Inhibitors of Topoisomerase DNA Religation
High throughput screen for compounds that modulate topoisomerase activity

S08001: Emerson

Epigenetic Silencing of Tumor Suppressor Genes
Epigenetic silencing of tumor suppressor genes occurs through loss of CTCF binding and chromatin boundaries

S96024A: Evans

Treatment of Disease States which Result from Neoplastic Cell Proliferation Using PPAR-gamma Activators and Compositions Useful Therefor
Administration of PPAR-gamma agonists, optionally in combination with RXR specific agonists, can block neoplastic cell proliferation

S96023A: Evans

Treatment of Liposarcomas Using a Combination of Thiazolidinediones and Retinoid X Receptor Selective Agonists
Compositions useful for the treatment of liposarcomas

S98015: Gage

Transcription Factor Regulating FGF-2 and Variants Thereof
Genes which encode polypeptides that are FGF-2 regulators of transcription

S96027: Rivier

Gonadotropin Releasing Hormone (GnRH) Analogs
Potent GnRH antagonists with significantly increased duration of action, useful for applications including fertility regulation, endometriosis, hormone-dependent tumors, and precocious puberty.

S09022: Shaw

Imaging and Treatment of Intestinal Cancer: Peutz-Jeghers Syndrome
Gastrointestinal Disease or Disorder Imaging and Treatment

S08023: Thomas

Non-Mammalian Animal Models with Glioma for Cancer Discovery
Gliomas, neoplasms of glial cells and their precursors, are the most common malignant tumors of the central nervous system (CNS).