Technology for CNS Applications
S06007: Callaway
Understanding Neural Networks: Identifying Monosynaptic Connections
Technology that enables specific labeling and/or manipulation of neural networks
S09023: Gage
A New Diagnostic Assay: Measuring Retrotransposition in Man
L1 retrotransposition in human neural progenitor cells
S09001: Gage
Computational Model of Neurogenesis
Role of Neurogenesis in Pattern Separation Neural Networks
S08017: Gage
Pluripotent Stem Cells from Neuronal Cells
Transcriptional analysis of virus-free human induced pluripotent cells
S08014: Gage
Human Cell Assay for Amyotrophic Lateral Sclerosis (ALS)
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative adult disease characterized by fatal paralysis in both the brain and spinal cord motor neurons due to motor neuron death.
S04010: Gage
A Molecular Switch Regulating Neurogenesis
A "master switch" that determines whether the genetic program that mediates neural differentiation is repressed or activated
S98035: Gage
Regulation of Tyrosine Hydroxylase Expression
Nurr1 polypeptide upregulates tyrosine hydroxylase activity and promotes expression of DOPA, norepinenephrine and epinephrine.
S00007: Heinemann
Kainate Receptor Subunit GluR7 Polymorphisms for Diagnosing Predisposition and for Therapy of Mood Disorders
The Kainate Receptor Subunit GluR7 Gene is Associated with Mood Disorders
S05002: Lee
Nerve Regeneration: Compositions and Methods
Methods and compositions for promoting nerve growth and/or regeneration, including what is believed to be the first demonstration of locomotor functional recovery following a complete spinal cord transection.
S08010: OLeary
Controlling Axon Growth and Mapping in the Visual System
Axonal connections in the mature nervous system are extraordinarily precise.
S96032: Rivier
Corticotropin-Releasing Factor (CRF) Antagonists
Drugs to activate CRF receptors based on peptide antagonists
S06017: Slesinger
Kir Channel Modulators
Methods and materials for modulating Kir channel activity and identification of related compounds.
S96012: Vale
Urocortin
A native mammalian peptide with potent hypotensive activity used as a therapeutic or target
S93011: Vale
Corticotropin-Releasing Factor Overproducing Transgenic Mice
Transgenic mouse useful to screen compounds that modulate corticotropin-releasing factor levels
