Salk Institute

New Technology

New Technologies

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S06007: Callaway

Understanding Neural Networks: Identifying Monosynaptic Connections
Technology that enables specific labeling and/or manipulation of neural networks

S08013: Chory

A Zinc Protein That Controls Morning-specific Growth in Plants
Growth in plants is modulated by a complex interplay between internal signals and external cues.

S08001: Emerson

Epigenetic Silencing of Tumor Suppressor Genes
Epigenetic silencing of tumor suppressor genes occurs through loss of CTCF binding and chromatin boundaries

S09026: Evans

Adipose-derived Induced Pluripotent Stem Cells
Model system for studying the molecular mechanisms of feeder-free iPS generation and maintenance

S09023: Gage

A New Diagnostic Assay: Measuring Retrotransposition in Man
L1 retrotransposition in human neural progenitor cells

S09001: Gage

Computational Model of Neurogenesis
Role of Neurogenesis in Pattern Separation Neural Networks

S08017: Gage

Pluripotent Stem Cells from Neuronal Cells
Transcriptional analysis of virus-free human induced pluripotent cells

S08014: Gage

Human Cell Assay for Amyotrophic Lateral Sclerosis (ALS)
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative adult disease characterized by fatal paralysis in both the brain and spinal cord motor neurons due to motor neuron death.

S09011: Izpisua Belmonte

Increased Reprogramming for Generating Pluripotent Stem Cells
Induced pluripotent stem (iPS) cell generation using two factors and p53 inactivation

S09007: Izpisua Belmonte

A Step Toward Safe Derivation of Clinically Relevant Human Induced Pluripotent Stem Cells
A single plasmid construct that expresses four transcription factors from one polycistronic unit

S08024: Izpisua Belmonte

Production of Induced Pluripotent Stem Cells: Generation from a Single Hair
Induced Pluripotent Stem Cells and Methods of Use

S08022: Lemke

A Novel Animal Model for Studying Anticoagulants: Protein S Deficient Mice
Protein S (ProS) is a blood anticoagulant, and ProS deficiencies are associated with venous thrombosis, stroke, and autoimmunity.

S08010: OLeary

Controlling Axon Growth and Mapping in the Visual System
Axonal connections in the mature nervous system are extraordinarily precise.

S09022: Shaw

Imaging and Treatment of Intestinal Cancer: Peutz-Jeghers Syndrome
Gastrointestinal Disease or Disorder Imaging and Treatment

S08023: Thomas

Non-Mammalian Animal Models with Glioma for Cancer Discovery
Gliomas, neoplasms of glial cells and their precursors, are the most common malignant tumors of the central nervous system (CNS).

S08005: Verma

IKK2: A Central Player in Allergic Reactions
Methods of identifying IKK2 activators or inhibitors for regulation of mast cell degranulation

S09008: Wang

Increasing Unnatural Amino Acid Incorporation 5-Fold in Mammalian Cells
Improved orthogonal tRNA-synthetase recognition for efficient unnatural amino acid incorporation and application in mammalian cells

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