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Salk News


Richard A. Murphy Appointed President and CEO of The Salk Institute

La Jolla, CA – Richard A. Murphy, director of the Montreal Neurological Institute (MNI), has been named president and chief executive officer of The Salk Institute, effective October 1.


Humanized Mouse To Become Basic Tool To Test Drug-Drug Interactions

La Jolla, CA – A genetically engineered mouse, equipped with a human gene that senses potentially toxic substances in the body, including drugs, has been created by scientists at The Salk Institute.


Cancer “Survival” Structure Deciphered By Salk Scientists

La Jolla, CA – It’s a molecule that endows cancer cells with their pernicious ability to persevere.


Chromosome Copying: Salk Scientists Identify Unique Mechanism

La Jolla, CA – Before the moment of conception, living organisms experience another distinct birth – the creation of healthy eggs and sperm. Salk scientists recently obtained a peek at how genetic material is copied during the process, called meiosis, that produces these sex cells.


First Genes To Control Cortex Identity Discovered By Salk Scientists

La Jolla, CA – Salk Institute neuroscientists have obtained the first evidence that specific genes control how the cortex forms functional units during development. The cortex is the most recently evolved part of the mammalian brain and, in humans, governs abstract reasoning and symbolic thought.


Single Gene Deficiency Makes Mice “Neurotic”

La Jolla, CA – Mice are not usually noted for their stalwart natures, but a new Salk Institute study shows that the loss of a single gene can render them especially anxious. The resulting “neurotic” mice approach new situations tentatively and appear to experience stress more acutely than normal mice.


We Live In The Past, Salk Scientists Discover

La Jolla, CA – If you think you?re living in the past, you’re right – and science can tell you just how far behind the times you are. According to a new Salk study, it’s at least 80 milliseconds, just slightly longer than the blink of an eye.


Potential Male Contraceptive Target Discovered by Salk Scientists

La Jolla, CA – The first gene to control male fertility without affecting sexual behavior or physical appearance has been identified by Salk researchers. The study, appearing in the current Nature Genetics, demonstrates that a certain genetic mutation eliminates sperm development in male mice. It has no effect on females.


Plant “DWARF” Gene Found By Salk Scientists

La Jolla, CA – Manicuring golf courses and the ritual mowing of suburban lawns may soon be relegated to history with the discovery of a new “dwarf” gene that limits plant stem length.


HIV Movement Visualized by Salk Scientists

La Jolla, CA – A new technique developed by Salk scientists allows the first glimpse of HIV inside a living cell and shows how the virus advances toward its ultimate target, the nucleus.


Gene That Speeds Maturation In Plants Isolated By Scientists At The Salk Institute

La Jolla, CA – A gene that speeds up the maturation process in plants, resulting in earlier development and flowering, has been isolated by a team of scientists at The Salk Institute.


Structure of Molecular Scissors Critical for the Shaping of Cells Revealed by Structural Biologists at The Salk Institute

La Jolla, CA – The living cell is the prototypical shape-shifter. At any given moment, it will reorganize itself to move, grow, replicate and even die.


Exercise Makes Mice Smarter, Salk Scientists Demonstrate

La Jolla, CA – Should you hit the treadmill before hitting the books?


Vitamin A Shown To Be Critical For Heart Location In Vertebrate Animals

La Jolla, CA – To make sure your heart’s in the right place, you need to add just the right amount of vitamin A.


Finding Suggests New Therapy For Genetic Disorder

La Jolla, CA – A home movie of toddlers will show them wobble and weave, often to the amusement of adult viewers. But for babies born with the rare genetic disease ataxia-telangiectasia, commonly known as A-T, what may seem like normal and adorable lack of polish accelerates into a progressive and pervasive loss of muscle control and early death.


Plant Enzyme Important For Nutraceuticals Deciphered By Salk Scientists

La Jolla, CA – The three-dimensional structure of a linchpin enzyme plants need to thrive – and one viewed as a key player in the growing nutraceutical market – has been revealed in atomic detail by scientists at The Salk Institute.


Flower Pattern Switch Found By Salk Scientists

La Jolla, CA – During the turbulent ’60s, the phrases “flower power” and “petal power” were counterculture slogans that invoked peace and love. Though science has yet to design flowers capable of fulfilling the wishes of a bygone era, researchers at The Salk Institute are learning more about the genetic power behind flower formation that one day could yield designer blooms.


Plant Genome Project Leader Joins The Salk Institute

La Jolla, CA – Joseph R. Ecker, one of the nation’s leading authorities on the molecular biology and genetics of plants, will be joining the faculty of The Salk Institute, effective next summer.


Gene Switches Wing To Leg, Salk Scientists Find

La Jolla, CA – A single gene can transform embryonic tissue destined to form a wing into a leg instead, Salk Institute investigators have found. Their studies were performed in chickens, and the gene, called Tbx4 , appears to be involved in limb formation in mammals as well, including humans.


Mice cured of hemophilia by Salk gene therapy protocol

La Jolla, CA – With the aid of a common virus used to ferry a clotting factor gene into liver cells, a team led by researchers at The Salk Institute for Biological Studies has cured a form of hemophilia in mice.