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Salk Scientists Provide New Mouse Model For Autoimmunity

La Jolla, CA – Salk scientists have created an animal model for autoimmune diseases that closely mirrors the perplexing patterns of symptoms observed in human autoimmunity, including an increased susceptibility of females over males.

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Study Led By Salk Scientists Answers Long-Sought Question: Where Do Flowers Come From?

La Jolla, CA – Though a rose, carnation or tulip each has its own distinguishing feel, look and smell, they all share one common trait: the flower's petals adorn its perimeter while the reproductive organs sit in the flower's center.

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Neural Progenitor Cells Recovered From Postmortem And Adult Tissue

La Jolla, CA – Salk Institute scientists have isolated cells from the brains of human cadavers that can grow, divide and form specialized classes of brain cells. Their findings indicate that postmortem tissue may be a potential source of multipotent stem cells, with a variety of uses and applications.

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Synapse Formation Triggered By Muscle, Salk Scientists Show

La Jolla, CA – Sometimes nerve is all you need. But nerves have needs, too, including the use of synapses – tiny junctions that coordinate communication between nerves and the muscles they control.

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New Potential Drug Target In HIV Enzyme

La Jolla, CA – A Salk Institute-led team of scientists has identified a new site on the HIV enzyme integrase for potential drug therapy. Integrase is the only HIV enzyme not targeted by current drugs; reverse transcriptase and protease are blocked by drugs such as AZT and the protease inhibitors.

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Salk Scientists Find Genes That Control Limb Formation In Vertebrates

La Jolla, CA – Whether they're wings, fins or legs, those appendages generally known as limbs play a critical role for lifting, grasping, moving and other activities needed to sustain life.

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Running Boosts Brain Cell Numbers in Neurodegenerative Disease Model

La Jolla, CA – Scientists at The Salk Institute have shown that running can boost brain cell survival in animals with neurodegenerative disease.

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First Plant Genome Sequenced: Salk Scientists Part Of International Effort

La Jolla, CA – The first complete genome sequence of a plant appears in the current issue of Nature. Salk Professor Joseph R. Ecker, co-director of one of six contributing sequencing groups, expects the sequence to greatly accelerate efforts to improve the yield and hardiness of crop plants.

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Vitamin A Deficiency Impairs Learning Functions In Reversible Manner

La Jolla, CA – Removing Vitamin A from the diets of mice diminishes chemical changes in the brain considered the hallmarks of learning and memory. When vitamin A is added back to their diets, the impairment is reversed.

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"Gene Chips" Offer First Look at Genetic Behavior In Brain

La Jolla, CA – Salk scientists have obtained the first snapshot of how gene behavior varies among mammalian brains. The study employed "gene chip" technology to simultaneously compare the activities of approximately 13,000 genes in two inbred strains of mice.

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