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Gene Therapy Postpones Lou Gehrig's Disease Symptoms

La Jolla, CA – A unique gene therapy method postpones the symptoms and nearly doubles the life span in a mouse animal model of Lou Gehrig's disease, a research team led by the Salk Institute has found.

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Missing Enzyme Found to Lead to Alzheimer?s Disease Symptoms

La Jolla, CA – An enzyme studied by scientists for years can prevent tangles of proteins from forming in the brain's nerve cells – as occurs in patients with age-dependent Alzheimer's disease, according to a study by investigators at the Salk Institute, Beth Israel Deaconess Medical Center and Harvard Medical School.

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Salk Study Advances Understanding of Plant Genes and Their Function

La Jolla, CA – A Salk Institute study provides significant new information in the process of allowing scientists to understand the function of plant genes. The study is published in the August 1 issue of Science.

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Leila Josefowicz to Perform at Symphony at Salk

La Jolla, CA – The eighth annual Symphony at Salk, a benefit for the Salk Institute for Biological Studies, will be held Saturday, Aug. 23, under the stars on the institute's Gildred Court.

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HIV Inactivates the Body's Cellular Smart Bomb

La Jolla, CA – HIV eludes one of the body's key smart bomb defenses against infection, and this finding may lay the groundwork for new drugs to treat AIDS, according to a new Salk Institute study.

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Salk Researcher Wins Major National Institutes of Health Grant for Work on Brain-Immune Interactions, Potential Autoimmune Disease Treatments

La Jolla, CA – A Salk Institute scientist has been awarded a $3.3 million grant and the Jacob Javits Award from the National Institutes of Health (NIH) for his work in identifying how the immune and nervous systems interact to ward off disease, which may result in treatments for such autoimmune diseases as multiple sclerosis.

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Salk Scientists Identify Pathway That Determines When Plants Flower

La Jolla, CA – Salk scientists have defined a new pathway that controls how plants flower in response to shaded, crowded conditions, and their findings may have implications for increasing yield in crops ranging from rice to wheat.

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Cell Receptor Controls Body Fat Despite Food Consumption

La Jolla, CA – A cellular receptor that helps tailor responses to stress also keeps the body lean despite high-fat diets, a Salk Institute research team has found. But this leanness only appears under certain conditions, including a high-fat diet.

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Salk Professor Ronald Evans Awarded Two Major Prizes

La Jolla, CA – Professor Ronald Evans, the March of Dimes Chair in Molecular and Developmental Biology, has received the 2003 March of Dimes Prize in Developmental Biology for his pioneering the molecular pathways that lead to the most common chronic diseases affecting humans. He has also been awarded the Alfred P. Sloan Prize, one of three awards given annually by the General Motors Cancer Research Foundation.

The March of Dimes Prize is given every year to scientists whose research has profoundly advanced understanding of birth defects. The Sloan Prize is given for the most outstanding recent contribution in basic science related to cancer research.

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Male Sex Hormones Cooperate With Breast Cancer Gene To Suppress Tumors, Salk Scientists Find

La Jolla, CA – BRCA-2, a gene linked with breast and ovarian cancer, cooperates with male sex hormones to enhance its ability to activate transcription of genes, which may suppress tumor formation in normal cells, Salk Institute researchers have found.

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