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Researchers solve mystery of how nuclear pores duplicate before cell division

La Jolla, CA – Researchers have long wondered how nuclear pores – the all-important channels that control the flow of information in and out of a cell's nucleus – double in number to prepare for the split to come when a cell divides. Now, for the first time, scientists at the Salk Institute for Biological Studies watched as new funnel-like pore structures formed from scratch, and inserted themselves into the nuclear membrane.


Salk research challenges concept that motion perception is all black and white

La Jolla, CA – Researchers at the Salk Institute for Biological Studies have discovered a neural circuit that is likely to play an important role in the visual perception of moving objects. Their finding, published in the April issue of the journal Neuron, forces neurobiologists to rethink the neural pathways that our brain relies on to detect motion.


New model of p53 regulation proposed that suggests novel anticancer strategy

La Jolla, CA – Genetically engineered mice convinced scientists at the Salk Institute for Biological Studies that it was time to overhaul widely held beliefs about how a powerful tumor suppressor called p53 is controlled in cells. Their new model of p53 regulation has important implications for the development of anticancer drugs.



La Jolla, CA – On April 10, 2006, the Salk Institute revealed the latest version of its Master Plan Update. This long-term development plan will serve as a blueprint for the growth and development of the Institute for the next 50 years. The updated plan stays true to the original vision for the campus developed by Jonas Salk and Louis Kahn, and will allow the Institute to remain a world leader in the rapidly evolving world of basic medical research.


Salk scientist Ron Evans wins 2006 Gairdner Award for his discovery of hormone sensors

La Jolla, CA – Ronald M. Evans, Ph.D., professor and head of the Gene Expression Laboratory of the Salk Institute for Biological Studies, has been named a 2006 winner of the prestigious Gairdner Award for his pioneering research into nuclear hormone receptors.


Four of the Nation's Preeminent Research Institutions Announce Stem Cell Research Alliance

La Jolla, CA – Salk Institute professor Ursula Bellugi, who pioneered the study of the biological foundation of language, has been elected a member of the National Academy of Sciences. The Academy made the announcement today during its 144th annual meeting in Washington, DC. Election to the Academy recognizes distinguished and continuing achievements in original research, and is considered one of the highest honors accorded a U.S. scientist.


For the first time: longevity modulated without disrupting life-sustaining function

La Jolla, CA – For the first time ever, researchers at the Salk Institute have pinpointed a protein specifically responsible for extending lifespan and youthfulness without disrupting an organism's response to some forms of stress, development and fertility controlled by the insulin signaling pathway.


Salk researchers make fast strides towards understanding how our body controls walking

La Jolla, CA – Researchers at the Salk Institute for Biological Studies have identified an important circuit in the spinal cord that controls the speed with which our leg muscles contract and relax. Their findings mark an important milestone in understanding the neural circuitry that coordinates walking movements – one of the main obstacles in developing new treatments for spinal cord injuries.


Salk Board of Trustees adds three prominent San Diegans to its leadership

La Jolla, CA – Dr. Irwin Jacobs, co-founder of QUALCOMM; Richard Freeman, president and chief operating officer of the San Diego Padres; and Ted Waitt, co-founder of Gateway, have been named to the positions of vice chair of the Salk Institute's Board of Trustees. They join vice chair, Dr. Jennifer Howse, president of the March of Dimes; and Jerry Kohlberg, chairman of the Board of Trustees, to form the upper echelon of board leadership for the Salk Institute.


"Jumping genes": new target for body's innate immune protection system against viruses

La Jolla, CA – When HIV and other retroviruses invade a cell in the human body, a fierce battle ensues between the intruder and the cell's defense team: members of the APOBEC family, a handful of closely related antiviral proteins that try to disarm the invading virus by scrambling its genetic information.


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