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The Salk Institute announces $10 million challenge gift from Irwin and Joan Jacobs

La Jolla, CA – The Salk Institute announced today that Irwin and Joan Jacobs have established a $10 million matching fund to support the creation of 10 Senior Scientist Endowed Chairs. By providing a match, this fund enables 10 donors to each make a gift of $2 million to create and name a highly prestigious and permanent chair. The Irwin and Joan Jacobs Leadership Challenge will add a $1 million match to each gift, thus providing each Chair with a $3 million endowment. Each named chair will provide key support to a Salk Institute Senior scientist.


A place in the sun

La Jolla, CA – Those spindly plants that desperately try to reach for a break in the canopy formed by larger plants all suffer from the same affliction: Shade avoidance syndrome or SAS. Now, the molecular details of SAS have been brought to light by researchers at the Salk Institute for Biological Studies.


Salk scientist wins 2007 Young Investigator's Award in Gene Therapy for Cancer

La Jolla, CA – Dr. Clodagh O'Shea, an assistant professor in the Molecular and Cellular Biology Laboratory at the Salk Institute for Biological Studies, has been selected for the 2007 Young Investigator's Award in Gene Therapy for Cancer. She will receive $500,000 over a three-year period to develop the "next generation oncolytic adenoviruses for p53-selective tumor therapy."


Vicki Lundblad to receive 2008 Pearl Meister Greengard Prize

La Jolla, CA – The fifth annual Pearl Meister Greengard Prize, an international award to recognize outstanding women scientists, has been awarded to Salk professor Vicki Lundblad, Ph.D., for her groundbreaking work in telomere biology.


How worms protect their chromosomes: Thereby hangs a surprising tail

La Jolla, CA – A team of scientists at the Salk Institute for Biological Studies has discovered that the roundworm C. elegans constructs the protective tips of its chromosomes – known as telomeres – with a little more panache than do mammals, a finding that could deepen our understanding of the interrelationship of aging and cancer.


Chronically elevated blood sugar levels disable "fasting switch"

La Jolla, CA – Continually revved up insulin production, the kind that results from overeating and obesity, slowly dulls the body's response to insulin. As a result, blood sugar levels start to creep up, setting the stage for diabetes-associated complications such as blindness, stroke and renal failure. To make matters even worse, chronically elevated blood sugar concentrations exacerbate insulin resistance.


UC San Diego and Salk Institute Establish Center to Study the Origin of Humans

La Jolla, CA – Perhaps the oldest question in the world is "where do I come from?"


New potential drug target for the treatment of atherosclerosis

La Jolla, CA – A nuclear receptor protein, known for controlling the ability of cells to burn fat, also exerts powerful anti-inflammatory effects in arteries, suppressing atherosclerosis in mice prone to developing the harmful plaques, according to new research by scientists at the Salk Institute for Biological Studies and the Harvard School of Public Health.


Salk researchers uncover molecular connection between excessive nutrient levels and insulin resistance

La Jolla, CA – For quite some time now, scientists suspected the so-called hexosamine pathway – a small side business of the main sugar processing enterprise inside a cell – to be involved in the development of insulin resistance. But they could never quite put their finger on the underlying mechanism.


PNAS article by Salk scientists wins 2007 Cozzarelli Prize

La Jolla, CA – The editors of the Proceedings of the National Academy of Sciences (PNAS) selected the article "Targeted delivery of proteins across the blood-brain barrier" by Brian J. Spencer, Ph.D. and Inder M. Verma, Ph.D., for the 2007 Cozzarelli Prize, which recognizes papers that reflect the highest standards of scientific excellence and originality.


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