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Cancer stem cells can go it alone

La Jolla, CA – At the heart of most, if not all cancers, lie a handful of wayward stem cells that feed the ever growing tumor mass, but their scarcity make it difficult for scientists to study them. Now, times of plenty may lie ahead as a breast cancer cell line – established long ago – turned out to behave a lot like cancer stem cells.

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Salk Institute receives a $2.3 million stem cell research facility grant

La Jolla, CA – The Salk Institute for Biological Studies was awarded a $2.3 million share of the stem cell research facilities grants approved by the governing board of the California Institute for Regenerative Medicine (CIRM) on June 5.

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Tony Hunter receives Robert. J. and Claire Pasarow Award for Cancer Research

La Jolla, CA – Salk scientist Dr. Tony Hunter is the recipient of the 2006 Pasarow Award in Cancer Research for his key discoveries of the chemical "switch" that turns healthy cells into cancer cells.

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Salk researchers successfully deliver protein across the blood-brain barrier

La Jolla, CA – Researchers at the Salk Institute for Biological Studies have overcome a long-standing problem in biology by equipping a protein with a small homing device, allowing it to slip behind the blood-brain barrier. Circumventing this barrier – specifically designed to keep substances out of the brain – is a crucial step for the delivery of drugs to the central nervous system (CNS).

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Newborn neurons like to hang with the in-crowd

La Jolla, CA – Like any new kid on the block that tries to fit in, newborn brain cells need to find their place within the existing network of neurons. The newcomers jump right into the fray and preferentially reach out to mature brain cells that are already well connected within the established circuitry, report scientists at the Salk Institute for Biological Studies in the online edition of Nature Neuroscience.

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Board of Trustees for the Salk Institute Appoints EVP/COO

La Jolla, CA – The Salk Institute for Biological Studies today announced the appointment of Dr. Marsha A. Chandler to the new position of Executive Vice President/Chief Operating Officer. The Salk Board of Trustees unanimously approved the appointment at its meeting in New York City on April 26.

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Salk researchers discover first gene that specifically links calorie restriction to longevity

La Jolla, CA – In studies going back to the 1930's, mice and many other species subsisting on a severely calorie-restricted diet have consistently outlived their well-fed peers by as much as 40 percent. But just how a diet verging on the brink of starvation extends lifespan has remained elusive.

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Salk scientist Ursula Bellugi elected to National Academy of Sciences

La Jolla, CA – Salk Institute professor Ursula Bellugi, who pioneered the study of the biological foundation of language, has been elected a member of the National Academy of Sciences. The Academy made the announcement today during its 144th annual meeting in Washington, DC. Election to the Academy recognizes distinguished and continuing achievements in original research, and is considered one of the highest honors accorded a U.S. scientist.

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Salk scientists hammer out a pathway that promotes muscle cell survival in mice

La Jolla, CA – Scientists at the Salk Institute for Biological Studies have identified an enzyme that pumps up a cell's ability to maintain healthy muscle and restores normal muscle function in genetically engineered mice with weak muscles. The study, published online in Nature Medicine, is the first to explore the part this enzyme plays in a cascade of events triggered by exercise-induced hormones and other signals.

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Salk Scientist Ronald M. Evans Receives America's Top Prize in Medicine

La Jolla, CA – Ronald M. Evans, Ph.D., Professor in the Salk Institute's Gene Expression Laboratory and a Howard Hughes Medical Investigator, has been named a recipient of the 2007 Albany Medical Center Prize in Medicine and Biomedical Research – America's top prize in medicine.

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