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Salk researchers successfully reprogram keratinocytes attached to a single hair

The first reports of the successful reprogramming of adult human cells back into so-called induced pluripotent stem (iPS) cells, which by all appearances looked and acted liked embryonic stem cells created a media stir. But the process was woefully inefficient: Only one out of 10,000 cells could be persuaded to turn back the clock.


Salk Scientist Fred H. Gage to Receive the Keio Medical Science Prize

La Jolla – Salk researcher Dr. Fred H. Gage, professor in the Laboratory of Genetics, has been awarded the Keio Medical Science Prize for his discovery of the physiological role of adult neurogenesis in mammalian brains. He will officially receive the award during a ceremony at Keio University's School of Medicine in Japan on Nov. 21.


Salk Researcher Terry Sejnowski Elected to Institute of Medicine

La Jolla, CA – Terry Sejnowski, Ph.D., professor and head of the Computational Neurobiology Laboratory at the Salk Institute has been elected to the Institute of Medicine, the IOM has announced. Election to the IOM is considered one of the highest honors in the fields of health and medicine and recognizes individuals who have demonstrated outstanding professional achievement and commitment to service.


Salk Institute Appoints Dr. William R. Brody as President

La Jolla, CA – The Salk Institute at a press conference today announced the appointment of Dr. William R. Brody, an acclaimed physician scientist and university leader, as the Institute's new president. Currently completing a 12-year tenure as president of The Johns Hopkins University, Dr. Brody is renowned for his achievements in biomedical engineering and his stellar academic career. He will assume his new role effective March 1, 2009.


A fine balance

La Jolla, CA – Once a toddler has mastered the art of walking, it seems to come naturally for the rest of her life. But walking and running require a high degree of coordination between the left and right sides of the body. Now researchers at the Salk Institute for Biological Studies have shown how a class of spinal cord neurons, known as V3 neurons, makes sure that one side of the body doesn't get ahead of the other.


Food for thought–regulating energy supply to the brain during fasting

La Jolla, CA – If the current financial climate has taught us anything, it's that a system where over-borrowing goes unchecked eventually ends in disaster. It turns out this rule applies as much to our bodies as it does to economics. Instead of cash, our body deals in energy borrowed from muscle and given to the brain.


What HIV Needs

La Jolla, CA – The human immunodeficiency virus (HIV) only brings along a minimalist's survival gear and relies on its host cell to provide what's missing. Now, a new study provides novel insight into how the virus exploits cellular functions to take up house in infected cells.


Salk Investigator Lei Wang Receives NIH New Innovator Award

La Jolla, CA – Salk researcher Dr. Lei Wang has been named a 2008 recipient of the National Institutes of Health Director's New Innovator Award. He joins a group of young scientists who will receive a portion of more than $138 million in support of innovative approaches to biomedical research.


Looking versus seeing

La Jolla, CA – The superior colliculus has long been thought of as a rapid orienting center of the brain that allows the eyes and head to turn swiftly either toward or away from the sights and sounds in our environment. Now a team of scientists at the Salk Institute for Biological Studies has shown that the superior colliculus does more than send out motor control commands to eye and neck muscles.


Biologists Identify Genes Controlling Rhythmic Plant Growth

La Jolla, CA – A team of biologists from the Salk Institute for Biological Studies, UC San Diego, and Oregon State University has identified the genes that enable plants to undergo bursts of rhythmic growth at night and allow them to compete when their leaves are shaded by other plants.


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