LA JOLLA, CA—Growing evidence suggests that there may be a link between diabetes and Alzheimer's disease, but the physiological mechanisms by which diabetes impacts brain function and cognition are not fully understood. In a new study published in Aging Cell, researchers at the Salk Institute for Biological Studies show, for the first time, that diabetes enhances the development of aging features that may underlie early pathological events in Alzheimer's.

LA JOLLA, CA—Scientists have long believed that glioblastoma multiforme (GBM), the most aggressive type of primary brain tumor, begins in glial cells that make up supportive tissue in the brain or in neural stem cells. In a paper published October 18 in Science, however, researchers at the Salk Institute for Biological Studies have found that the tumors can originate from other types of differentiated cells in the nervous system, including cortical neurons.

LA JOLLA, CA—By reprogramming skin cells from Parkinson's disease patients with a known genetic mutation, researchers at the Salk Institute for Biological Studies have identified damage to neural stem cells as a powerful player in the disease. The findings, reported online October 17, 2013 in Nature, may lead to new ways to diagnose and treat the disease.

LA JOLLA, CA—Cold viruses generally get a bad rap—which they've certainly earned—but new findings by a team of scientists at the Salk Institute for Biological Studies suggest that these viruses might also be a valuable ally in the fight against cancer.

LA JOLLA, CA—Based on two new studies by researchers at the Salk Institute for Biological Studies, regeneration of a new limb or organ in a human will be much more difficult than the mad scientist and supervillain, Dr. Curt Connors, made it seem in the Amazing Spider-man comics and films.

LA JOLLA, CA—Salk scientists have identified a unique molecular signature in induced pluripotent stem cells (iPSCs), "reprogrammed" cells that show great promise in regenerative medicine thanks to their ability to generate a range of body tissues.

LA JOLLA, CA—Scientists at the Salk Institute for Biological Studies have discovered a key genetic switch by which plants control their response to ethylene gas, a natural plant hormone best known for its ability to ripen fruit, but which, under stress conditions, can cause wilted leaves, premature aging and spoilage from over-ripening. The findings, published August 30 in Science magazine, may hold the key to manipulating plants' ethylene on/off switch, allowing them to balance between drought resistance and growth and, therefore, decrease crop losses from drought conditions.