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Genetic Re-disposition: Combined stem cell-gene therapy approach cures human genetic disease in vitro

La Jolla, CA—A study led by researchers at the Salk Institute for Biological Studies, has catapulted the field of regenerative medicine significantly forward, proving in principle that a human genetic disease can be cured using a combination of gene therapy and induced pluripotent stem (iPS) cell technology. The study, published in the May 31, 2009 early online edition of Nature, is a major milestone on the path from the laboratory to the clinic.

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Salk Scientist Inder Verma to Receive 2009 Outstanding Achievement Award from American Society of Gene Therapy

La Jolla, CA—Salk Professor Inder M. Verma, Ph.D., one of the world's leading authorities on the development and use of engineered viruses for gene therapy, has been named the 2009 recipient of the American Society of Gene Therapy's Outstanding Achievement Award. The award recognizes an ASGT member who has conducted groundbreaking research or achieved a lifetime of significant scientific contributions to the field of gene therapy. Verma is only the second scientist honored with the society's Outstanding Achievement Award, which debuted in 2008.

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Salk Institute Scientist Plays Pivotal Role in More Than $100 Mill National "Stand Up To Cancer" Fundraising, Pancreatic Cancer Research "Dream Team"

La Jolla-More than three years ago, while serving as president-elect and then president of the American Association for Cancer Research (AACR), Salk scientist Geoff Wahl had an epiphany: cancer research needed a grassroots American fundraising movement reminiscent of the polio-inspired March of Dimes.

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Good fences make good neighbors:

La Jolla, CA-Our genome is a patchwork of neighborhoods that couldn't be more different: Some areas are hustling and bustling with gene activity, while others are sparsely populated and in perpetual lock-down. Breaking down just a few of the molecular fences that separate them blurs the lines and leads to the inactivation of at least two tumor suppressor genes, according to researchers at the Salk Institute for Biological Studies.

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Salk Scientist wins the 2009 McKnight Scholar Award

La Jolla, CA—Dr. Tatyana Sharpee, an assistant professor in the Laboratory for Computational Biology, has been named a 2009 McKnight Scholar. She will receive a grant of $225,000 over a three-year period to study "Discrete representation of visual shapes in the brain."

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Salk Receives $6.6 Million Grant to Develop Stem Cell-Based Treatments for Incurable Diseases

La Jolla, CA -- The Salk Institute for Biological Studies has been awarded a $6.6 million grant – the largest single award in the latest competition -- by the California Institute Regenerative Medicine (CIRM) for research aimed at translating basic science into clinical cures. The funds are part of $67.7 million Early Translational Grants CIRM provided to 15 research organizations on Wednesday.

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Salk scientist Marc Montminy elected to National Academy of Sciences

La Jolla, CA – Salk researcher Marc R. Montminy, M.D., Ph.D., a professor in the Clayton Foundation Laboratories for Peptide Biology, has been elected a member of the National Academy of Sciences, the nation's most prestigious honorary society for scientists. The Academy made the announcement today during its 146th annual meeting in Washington, DC.

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Salk Launches Center for Nutritional Genomics with $5.5 Million Grant from Helmsley Trust

La Jolla, CA -- The Salk Institute has received a $5.5 million grant from the Leona M. and Harry B. Helmsley Charitable Trust to launch the Salk Center for Nutritional Genomics. The new Center will employ a molecular approach to nutrition and its impact on the role of metabolism on the immune system, cancer, diabetes and lifespan, thereby increasing the understanding of how nutrients affect health.

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Repairing a 'bad' reputation?

La Jolla, CA—New research at the Salk Institute for Biological Studies casts the role of a neuronal growth factor receptor—long suspected to facilitate the toxic effects of beta amyloid in Alzheimer's disease—in a new light, suggesting the molecule actually protects the neuron in the periphery from beta amyloid-induced damage.

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How the retina works: Like a multi-layered jigsaw puzzle of receptive fields

La Jolla, CA—About 1.25 million neurons in the retina -- each of which views the world only through a small jagged window called a receptive field -- collectively form the seamless picture we rely on to navigate our environment. Receptive fields fit together like pieces of a puzzle, preventing "blind spots" and excessive overlap that could blur our perception of the world, according to researchers at the Salk Institute for Biological Studies.

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