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Salk scientists uncover new clues to repairing an injured spinal cord

LA JOLLA—Frogs, dogs, whales, snails can all do it, but humans and primates can't. Regrow nerves after an injury, that is—while many animals have this ability, humans don't. But new research from the Salk Institute suggests that a small molecule may be able to convince damaged nerves to grow and effectively rewire circuits. Such a feat could eventually lead to therapies for the thousands of Americans with severe spinal cord injuries and paralysis.

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Analysis of African plant reveals possible treatment for aging brain

LA JOLLA—For hundreds of years, healers in São Tomé e Príncipe—an island off the western coast of Africa—have prescribed cata-manginga leaves and bark to their patients. These pickings from the Voacanga africana tree are said to decrease inflammation and ease the symptoms of mental disorders.

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Memory relies on astrocytes, the brain's lesser known cells

LA JOLLA—When you're expecting something—like the meal you've ordered at a restaurant—or when or when something captures your interest, unique electrical rhythms sweep through your brain.

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New gene discovered that stops the spread of deadly cancer

LA JOLLA—Scientists at the Salk Institute have identified a gene responsible for stopping the movement of cancer from the lungs to other parts of the body, indicating a new way to fight one of the world's deadliest cancers.

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One injection stops diabetes in its tracks

LA JOLLA—In mice with diet-induced diabetes—the equivalent of type 2 diabetes in humans—a single injection of the protein FGF1 is enough to restore blood sugar levels to a healthy range for more than two days. The discovery by Salk scientists, published today in the journal Nature, could lead to a new generation of safer, more effective diabetes drugs.

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No extra mutations in modified stem cells, study finds

LA JOLLA—The ability to switch out one gene for another in a line of living stem cells has only crossed from science fiction to reality within this decade. As with any new technology, it brings with it both promise—the hope of fixing disease-causing genes in humans, for example—as well as questions and safety concerns. Now, Salk scientists have put one of those concerns to rest: using gene-editing techniques on stem cells doesn't increase the overall occurrence of mutations in the cells. The new results were published July 3 in the journal Cell Stem Cell.

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Salk Institute welcomes four new faculty

LA JOLLA—The Salk Institute is pleased to welcome a new full professor and three new assistant professors, all exceptional leaders in their respective fields. The new faculty will facilitate innovative and collaborative breakthroughs in understanding human health and disease.

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Some stem cell methods closer to "gold standard" than others

LA JOLLA—Researchers around the world have turned to stem cells, which have the potential to develop into any cell type in the body, for potential regenerative and disease therapeutics.

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First appointment in new Salk Fellows Program

LA JOLLA—The Salk has launched a new initiative called the Salk Fellows Program. The program brings scientists from broad disciplines to the Institute to trigger innovation and perpetuate the collaborative spirit of the Salk.

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Conrad T. Prebys gives $25 million to Salk Institute to support scientific research

LA JOLLA—The Salk Institute for Biological Studies has received a $25 million gift from San Diego philanthropist and former Salk trustee Conrad T. Prebys to support cutting-edge biological research on a wide range of diseases.

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