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Salk News
Scientists reveal potential link between brain development and breast cancer gene

LA JOLLA—Scientists at the Salk Institute have uncovered details into a surprising—and crucial—link between brain development and a gene whose mutation is tied to breast and ovarian cancer. Aside from better understanding neurological damage associated in a small percentage of people susceptible to breast cancers, the new work also helps to better understand the evolution of the brain.


Salk microflora researcher Janelle Ayres named Searle Scholar

LA JOLLA—Janelle Ayres, assistant professor at Salk Institute's Nomis Foundation Laboratories for Immunobiology and Microbial Pathogenesis, has received the prestigious Searle Scholar award, which each year is given to only 15 researchers in the fields of chemical and biological sciences.


Salk scientist Vicki Lundblad wins accolades

LA JOLLA—Vicki Lundblad, professor of the Salk Institute's Molecular and Cell Biology Laboratory, has been awarded the Becky and Ralph S. O'Connor Chair and elected a Fellow of the American Academy of Microbiology.


Skyping for science education: "SciChat" takes off

LA JOLLA — A new science outreach program promotes virtual interaction and learning between Salk Institute scientists and students at the Del Mar Hills Academy of Arts and Sciences in Del Mar, California.


Salk Institute and Stanford University to lead new $40 million stem cell genomics center

LA JOLLA—The Salk Institute for Biological Studies will join Stanford University in leading a new Center of Excellence in Stem Cell Genomics, created through a $40 million award by California's stem cell agency, the California Institute for Regenerative Medicine.


Natural plant compound prevents Alzheimer's disease in mice

LA JOLLA—A chemical that's found in fruits and vegetables from strawberries to cucumbers appears to stop memory loss that accompanies Alzheimer's disease in mice, scientists at the Salk Institute for Biological Studies have discovered. In experiments on mice that normally develop Alzheimer's symptoms less than a year after birth, a daily dose of the compound—a flavonol called fisetin—prevented the progressive memory and learning impairments. The drug, however, did not alter the formation of amyloid plaques in the brain, accumulations of proteins which are commonly blamed for Alzheimer's disease. The new finding suggests a way to treat Alzheimer's symptoms independently of targeting amyloid plaques.


Salk scientists identify factors that trigger ALT-ernative cancer cell growth

LA JOLLA, CA—Highly diverse cancers share one trait: the capacity for endless cell division. Unregulated growth is due in large part to the fact that tumor cells can rebuild protective ends of their chromosomes, which are made of repeated DNA sequences and proteins. Normally, cell division halts once these structures, called telomeres, wear down. But cancer cells keep on going by deploying one of two strategies to reconstruct telomeres.


Salk scientist Fred Gage named to National Academy of Inventors

LA JOLLA—Fred H. Gage, professor in the Salk Institute's Laboratory of Genetics and holder of the Vi and John Adler Chair for Research on Age-Related Neurodegenerative Disease, has been elected a Fellow of the National Academy of Inventors (NAI).


Missing molecule in chemical production line discovered

LA JOLLA, CA—It takes dozens of chemical reactions for a cell to make isoprenoids, a diverse class of molecules found in every type of living organism. Cholesterol, for example, an important component of the membranes of cells, is a large isoprenoid chemical. The molecule that gives oranges their citrusy smell and taste is an isoprenoid, as is the natural antimalarial drug artemisinin.


Salk Institute Board of Trustees elects two visionary business leaders

LA JOLLA, CA—The Salk Institute is pleased to announce that Alan D. Gold and David F. Hale have been elected to its Board of Trustees.


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