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Wahl Lab - Publications 1996-1998
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- Huang, L-c., Clarkin, K., and Wahl, G.M. (1996) p53 dependent cell cycle arrests are preserved in DNA-activated protein kinase deficient mouse fibroblasts. Cancer Research 56:2940-2944.
- Paulson, T.G., Wright, F., Parker, B., Russack, V., and Wahl, G.M. (1996) Microsatellite instability correlates with reduced survival and poor disease prognosis in breast cancer. Cancer Research 56:4021-4026.
- Jones, S.N., Sands, A.T., Hancock, A.R., Vogel, H., Donehower, L.A., Linke, S.P., Wahl, G.M., Bradley, A. (1996) Absence of a p53-independent role for Mdm2 in control of cell growth and tumorigenesis. Proc. Natl. Acad. Sci. USA 93:14106-14111.
- Aladjem, M., Brody, L., O'Gorman, S., and Wahl, G.M. (1997) Positive selection of FLP mediated unequal sister chromatid exchange products in mammalian cells. Mol. Cell. Biol. 17:857-861.
- Wahl, G.M., Linke, S.P., Paulson, T.G., and Huang, L-C. (1997) Cell Cycle Control of Genetic Stability, in Genomic Instability and Immortality in Cancer: Mammalian checkpoints and genetic instability. In Enrico Mihich (ed.), Proceedings of the 8th Annual Pezcoller Symposium, June 17-19, 1996, Trento, Italy. Plenum Publishing Co., New York 8:33-52
- Wahl, G.M., Linke, S.P., Paulson, T.G., and Huang, L-c. (1997) Checkpoint Controls and Cancer: Maintaining genetic stability through Tp53 mediated checkpoint control. In J. Tooze (ed.), Cancer Surveys. Cold Spring Harbor Laboratory Press, New York 29:183-219.
- Linke, S.P., Clarkin, K., and Wahl, G.M. (1997) p53 mediates permanent arrest over multiple cell cycles in response to g- irradiation1. Cancer Research 57:1171-1179.
- Di Leonardo, A., Hussain-Khan, S., Linke, S.P., Greco, V., Seidita, G., and Wahl, G.M. (1997) DNA rereplication in the presence of mitotic spindle inhibitors in human and mouse fibroblasts lacking either p53 or pRb function1. Cancer Research 57:1013-1019.
- Linke, S.P., Harris, M.P., Neugebauer, S.E., Clarkin, K.C., Shepard, H.M., Maneval, D.C., and Wahl, G.M. (1997) p53-mediated accumulation of hypophosphorylated pRb after the G1 restriction point fails to halt cell cycle progression. Oncogene 15:337-345.
- Aladjem, M. and Wahl, G.M. (1998) Mapping replication fork direction by leading strand analysis. Methods: A companion to Methods in Enzymology 13(3):281-292.
- Paulson, T.G., Almasan, A., Brody, L., and Wahl, G.M. (1998) Gene amplification in a p53-deficient cell line requires cell cycle progression under conditions that generate DNA breakage. Mol. Cell. Biol. 18(5):3089-3100.
- Shimizu, N., Itoh, N., Utiyama, H., and Wahl, G.M. (1998) Selective entrapment of extrachromosomally amplified DNA by nuclear budding and micronucleation during S-phase. J Cell Biol. 140(6):1307-1320
- Aladjem, M. I., Spike, B. T., Rodewald, L. W., Hope, T. J., Klemm, M., Jaenisch, R., and Wahl, G.M. (1998) ES cells do not activate p53 dependent stress responses and undergo p53-independent apoptosis in response to DNA damage. Current Biology 8:145-155.

