Wahl Lab

Wahl Lab - Publications 1986-1993

Current Publications | 2004-2006 | 2000-2003 | 1998-2000 | 1996-1998 | 1994-1996 | 1986-1993 | 1970-1986

  1. Wahl, G.M., Gaudray, P., Carroll, S. and Proctor, N. (1986) Is gene amplification inducible?  In: R. Dulbecco, V. De Vita, L. Santi, L. Zardi, eds.  Cancer Frontiers, Proceedings of the Second International Conference on Progress in Cancer Research.  The Humana Press, pp. 71-98.
  2. Wahl, G.M., Carroll, S., Gaudray, P., Meinkoth, J. and Ruiz, J. (1986). Applications of Gene Transfer in the Analysis of Gene Transfer in the Analysis of Gene Amplification.  In: Gene Transfer (R. Kucherlapati, ed), Plenum Publishing Corp., pp. 289-323.
  3. Wahl, G.M. and Richman, D.D. (1986). Nucleic Acid Probes to Detect Viral Diseases. In: Concepts in Viral Pathogenesis. (A.L. Notkins and M.B.A. Oldstone, Eds.) Springer-Verlag, New York, pp. 301-309.
  4. Meinkoth, J. and Wahl, G.M. (1987) Chapters concerning Nucleic Acid Hybridization in Guide to Molecular Cloning Techniques, Methods in Enzymology Vol. 152 (S.L. Berger and A.R. Kimmel, Eds.) New York Academic Press: Chapter 9, 399-407. Nick Translation.
  5. Wahl, G.M., Berger, S.L., Kimmel, A.R. Chapter 43, 91-94. Molecular Hybridization of Immobilized Nucleic Acids: Theoretical Concepts and Practical Considerations. 
  6. Wahl, G.M. and Berger, S.L. Chapter 45, 415-423. Screening Colonies or Plaques with Radioactive Nucleic Acid Probes.
  7. Wahl, G.M., Meinkoth, J. and Kimmel, A.R. Chapter 61, 572-581. Northern and Southern Blots.
  8. Evans, G.A. and Wahl, G.M. (1987) Cosmid Cloning Vectors: In Guide to Molecular Cloning Techniques, Methods in Enzymology Vol. 152 (S.L. Berger and A.R. Kimmel, Eds.) New York Academic Press: Chapter 65: 604-610. Cosmid Vectors for Genomic Walking and Rapid Restriction Mapping.
  9. Wahl, G.M., Carroll, S.M., Gaudray, P., deRose, M.L., Emery, J. and Von Hoff, D.D. (1987) High Frequency Amplification of a Transfected Gene via Excision of an Autonomously Replicating Episome. In Proceedings of the Workshop on the Role of DNA Amplification in Tumor Initiation and Promotion.  (H. zur Hausen and J.R. Schlehofer, Eds.) J. B. Lippincott Co., Philadelphia, pp. 45-57.
  10. Meinkoth, J.L., Killary, A., Fournier, R.E.K. and Wahl, G.M. (1987) Unstable and Stable CAD Gene Amplification:  Importance of Flanking Sequences and Nuclear Environment in Gene Amplification. Mol. Cell. Biol. 7:1415-1424.
  11. Wahl, G.M., Lewis, K.A., Ruiz, J.C., Rothenberg, B., Zhao, J. and Evans, G. (1987) Cosmid Vectors for Rapid Genomic Walking, Restriction Mapping and Gene Transfer.  Proc. Natl. Acad. Sci. USA 84:2160-2164.
  12. Carroll, S., Gaudray, P., DeRose, M.L., Emery, J.F., Meinkoth, J.L., Nakkim, E., Subler, M. and Wahl, G.M. (1987). Characterization of an Episome Produced in Hamster Cells that Amplify a Transfected CAD Gene at High Frequency: Functional Evidence for a Mammalian Replication Origin. Mol. Cell Biol. 7:1740-1750.
  13. Carroll, S., DeRose, M.L., Gaudray, P., Moore, C., Vandevanter, D.N., Von Hoff, D.D. and Wahl, G.M. (1988) Double Minute Chromosomes Can Be Produced From Precursors Derived From A Chromosomal Deletion. Mol. Cell. Biol. 8:1525-1533.
  14. Von Hoff, D.D., Needham-Vandevanter, D.R., Yucel, J., Windle, B.F. and Wahl, G.M. (1988) Amplified MYC Oncogenes Localized to Replicating Submicroscopic, Circular DNA Molecules. Proc. Natl. Acad. Sci. USA 85: 4804-4808.
  15. Ruiz, J.C. and Wahl, G.M. (1988) Formation of an Inverted Duplication Can Be an Initial Step in Gene Amplification. Mol. Cell. Biol. 8:4302-4313.
  16. Barclay, B.J., Huang, T., Nagel, M.G., Misener, V.L., Game, J.C., and Wahl, G.M. (1988) Mapping and sequencing of the dihydrofolate reductase gene (DFR1) of Saccharomyces cerevisiae. Gene 63:175-185.
  17. Ruiz, J., Choi, K., Von Hoff, D.D., Roninson, I.B. and Wahl, G.M. (1989) Autonomously Replicating Episomes Contain mdr-1 Genes in a Multidrug Resistant Human Cell Line.  Mol. Cell. Biol. 9:109-115.
  18. Wahl, G.M. (1989) The Importance of Circular DNA in Mammalian Gene Amplification.  Cancer Research 49:1333-1340.
  19. Stark, G.R., Debatisse, M., Wahl, G.M. and D. Glover (1989) DNA Amplification in Eukaryotes.  IRL Press, B.D. Hanes and D.M. Glover (eds.) Gene Rearrangement, pp 99-149.
  20. Stark, G.R., Debatisse, M., Giulotto E. and Wahl, G.M. (1989) Recent Progress in Understanding Mechanisms of Mammalian DNA Amplification. Cell 57:901-908.
  21. Ruiz, J. and Wahl, G.M. (1990) Chromosome Destabilization During Gene Amplification. Mol. Cell. Biol. 10:3056-3066.
  22. Barringer, K.J., Orgel, L., Wahl, G.M. and Gingeras, T.R. (1990) Blunt-end and Single-strand Ligation by Escherichia coli Ligase: Influence on an In Vitro Amplification Scheme. Gene 89:117-122.
  23. Windle, B., Draper, B., Yin, Y., O'Gorman, S.  and Wahl, G.M. (1991) A central role for chromosome breakage in gene amplification, deletion formation and amplicon integration. Genes and Dev. 5:160-174.
  24. O'Gorman, S., Fox, D.T. and Wahl, G.M. (1991) Recombinase-mediated gene activation and site-specific integration in mammalian cells. Science 251:1351-1355.
  25. Benner, S.E., Wahl, G.M. and Von Hoff, D.D. (1991) Double Minute Chromosomes and Homogeneously Staining Regions in tumors taken directly from patients versus in human tumor cell lines. Anticancer Drugs 2:11-25.
  26. Carroll, S., Trotter, J. and Wahl, G.M. (1991) Replication timing control can be maintained in extrachromosomally amplified genes. Mol. Cell. Biol. 11:4779-4785.
  27. Von Hoff, D.D., Waddelow, T., Forseth, B., Davidson, K., Scott, J. and Wahl, G.M. (1991) Hydroxyurea accelerates loss of extrachromosomally amplified genes from tumor cells. Cancer Research 51:6273-6279.
  28. Wahl, G.M., Carroll, S. M., and Windle, B.E. (1992) Cytogenetic and molecular dynamics of mammalian gene amplification: evidence supporting chromosome breakage as an initiating event. In Gene Amplification in Mammalian Cells:  A Comprehensive Guide R. Kellems, Ed., Marcel Dekker, Inc., New York, pages 513-531.
  29. Kimmel, M., Axelrod, D.E. and Wahl, G.M. (1992) A branching process model of gene amplification following chromosome breakage. Mutat. Res. 276: 225-239.
  30. Windle, B.E. and Wahl, G.M. (1992) Molecular dissection of mammalian gene amplification: new mechanistic insights revealed by analyses of very early events.  Mutat. Res. 276:199-224.
  31. Yin, Y., Tainsky, M.A., Bischoff, F.Z., Strong, L. C. and Wahl, G.M. (1992) Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles.  Cell 70:937-948.
  32. Nonet, G.H., Carroll, S.M., DeRose, M.L., Wahl, G.M. (1993) Molecular dissection of an extrachromosomal amplicon reveals a circular structure consisting of an imperfect inverted duplication. Genomics 15: 543-558.
  33. VonHoff, D.D., McGill, J.R., Forseth, B.J., Davidson, K.K., Bradley, T.P., Van Devanter, D.R., and Wahl, G.M. (1992) Elimination of extrachromosomally amplified c-Myc genes from human tumor cells reduces their tumorigenicity. Proc. Natl. Acad. Sci. 89: 8165-8169.
  34. Nonet, G. and Wahl, G.M. (1993) Introduction of YACs containing a putative mammalian replication origin into mammalian cells can generate structures that replicate autonomously. Somatic Cell Mol. Genet. 19:171-192.
  35. Carroll, S. M., DeRose, M.L., Kolman, J.L., Nonet, G. H., Kelly, R.E., and Wahl, G.M. (1993) Localization of a bidirectional DNA replication origin in native locus and in episomally amplified murine adenosine deaminase loci. Mol. Cell. Biol. 13: 2971-2981.
  36. Barclay, B.J., Ondrusek, N.K., Wildenhain, Y.D., Huang, T., Carlone, R.L., Clement, J-M., Wahl, G.M. (1993) Effect of genomic position on amplification of the DFR1 gene in saccharomyces cerevisiae. In Chemistry and Biology of Pteridines and Folates.  Eds. J. Ayling, M. Nair and C. Baugh, Plenum Press, New York.  338: 545-550.