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Shaw Laboratory Videos

New gene discovered that stops the spread of deadly cancer
July 17, 2014

Cancer Breakthrough in San Diego
July 18, 2014

Salk Scientists Find Diabetes Drug Treats Lung Cancer
January 29, 2013


Phenformin decreases size of lung tumors and increases survival in mice
January 30, 2013


Salk Institute receives $42M grant to research genetic factors that contribute to human diseases-
Funds awarded by Helmsley Charitable Trust
January 23, 2013


The Art and Science of Cuisine at the Salk Institute
January 23, 2014
Reuben Shaw, Isabel Cruz and Joy Houston. See more information and videos at

Treating Cancer with Diabetes Drugs...and other Adventures in Basic Biomedical Research
November 7, 2012
A presentation to the SalkExcellerators

"Fasting pathway" points the way to new class of diabetes drugs
May 12, 2011

A uniquely collaborative study by researchers at the Salk Institute for Biological Studies uncovered a novel mechanism that turns up glucose production in the liver when blood sugar levels drop, pointing towards a new class of drugs for the treatment of metabolic disease.

Their findings, published in the May 13, 2011, issue of the journal Cell, revealed a crucial role for so called histone deacetylases (HDACs), a group of enzymes that is the target of the latest generation of cancer drugs. HDACs get sugar production rolling when blood glucose levels run low after prolonged periods of fasting or during the night. Read more>>

How cells running on empty trigger fuel recycling
December 23, 2010

In a paper published in the Dec. 23, 2010 edition of Science Express, a team led by Reuben Shaw, PhD., Howard Hughes Medical Institute Early Career Scientist and Hearst Endowment assistant professor in the Salk's Molecular and Cell Biology Laboratory, reports that AMPK activates a cellular recycling process known as autophagy by activating an enzyme, known as ATG1, that jumpstarts the process. Read more>>


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