Anthony Grey Craig, Ph.D., Senior Staff Scientist


Research Interests

(i) Characterizing protein post-translational modifications
(ii) Sequencing of bio-polymers
(iii) Determining the structural arrangement of cyclic peptides
(iv) Bio-affinity capture of samples for mass spectrometry
(v) Modifying the glycan structures on glycoproteins to investigate bioactivity

Education

Ph. D. (Chemistry), 1984. University of New South Wales, Australia
B. Sc. (Hons.), 1979, La Trobe University, Victoria, Australia

Professional Society Memberships

American Chemical Society
American Society for Mass Spectrometry
American Association for the Advancement of Science
Protein Society

Selected Publications

Kirby, D. A., S. C. Koerber, A. G. Craig, R. D. Feinstein, L. Delmas, M. R. Brown and J. E. Rivier (1993). "Defining structural requirements for neuropeptide Y receptors using truncated and conformationally restricted analogues." J Med Chem 36: 385-393.

J. Gulyas, C. Rivier, M. Perrin, S. C. Koerber, S. Sutton, A. Corrigan, S. L. Lahrichi, A. G. Craig, W. Vale and J. Rivier (1995). Potent, structurally constrained agonists and competitive antagonists of corticotropin releasing factor (CRF). Proc. Natl. Acad. Sci., USA 92, 10575-10579

J. S. Martinez, B. M. Olivera, W. R. Gray, A. G. Craig, D. R. Groebe, S. N. Abramson and J. M. McIntosh (1995). a-Conotoxin EI, A New Nicotinic Acetycholine Receptor Antagonist with Novel Selectivity. Biochemistry 34, 14519-14526

J. E. Rivier, G.-C. Jiang, S. C. Koerber, J. Porter, A. G. Craig and C. Hoeger (1995). Betidamino acids: Versatile and constrained scaffolds for drug discovery. Proc. Natl. Acad. Sci. USA. 93, 2031-2036

Fischer, W. H., J. E. Rivier and A. G. Craig (1993). "In situ Reduction Suitable for Matrix Assisted Laser Desorption/Ionization and Liquid Secondary Ionization Mass Spectrometry Using Tris (2-carboxyethyl) phosphine." Rapid Commun Mass Spectrom 7: 225-228.

Craig, A. G., W. H. Fischer, J. E. Rivier and W. R. Gray (1994). MS Based Scanning Methodologies Applied to Conus Venom. Tech Prot Chem VI. San Diego, CA, Academic Press. J. W. Crabb ed. 31-38.

Craig, A. G., S. W. Sutton, J. Vaughan and W. H. Fischer (1995). Immunoprecipitation as a Means of Purification for Analysis with Mass Spectrometry. Tech Prot Chem VII. San Diego, CA, Academic Press. D. Marschak ed. (in press).

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