Publications

updated 11/07/02

2002 / 2001 / 2000 / 1999 / 1998

2002

Contractor, A. and Heinemann, S.F.

Glutamate receptor trafficking in synaptic plasticity. Science STKE 156:RE14 (2002). [Abstract]

Contractor, A., Rogers, C.A., Maron, C., Henkemeyer, M., Swanson, G.T. and Heinemann, S.F.

Trans-synaptic eph receptor-ephrin signaling in hippocampal mossy fiber LTP. Science 296:1864-1869 (2002). [Abstract]

Green, T., Rogers, C.A., Contractor, A., and Heinemann, S.F.

NMDA receptors formed by NR1 in Xenopus laevis oocytes do not contain the endogenous subunit XenU1. Molecular Pharmacology 61:326-333 (2002). [Abstract]

Kaspar, B.K., Vissel, B., Bengoechea, T., Crone, S., Randolph-Moore, L., Muller, R., Brandon, E.P., Schaffer, D., Verma, I.M., Lee, K.F., Heinemann, S.F. and Gage, F.H.

Adeno-associated virus effectively mediates conditional gene modification in the brain. Proc Natl Acad Sci U S A 99:2320-5 (2002). [Abstract]

Krupp, J.J., Vissel, B.,Thomas, C.G., Heinemann, S.F. and Westbrook, G.L.

Calcineurin Acts via the C-terminus of NR2A to modulate desensitization of NMDA receptors. Neuropharmacology 42:593-602 (2002). [Abstract]

Swanson, G.T., Green, T., Sakai, R., Contractor, A., Che, W., Kamiya, H. and Heinemann, S.F.

Differential activation of individual subunits in heteromeric kainate receptors. Neuron 34:589-98 (2002) [Abstract]

Vetter, D.E., Li, C., Zhoa, L., Contarino, A., Liberman, M.C., Smith, G.W., Marchuk, Y., Koob, G.F. Heinemann, S.F. Vale, W. and Lee, K.F.

Urocortin-deficient mice show hearing impairment and increased anxiety-like behavior. Nature Genetics : (2002). [Abstract]

Vissel, B., Krupp, J.J., Heinemann, S.F. and Westbrook, G.L.

Intracellular domains of NR2 alter calcium-dependent inactivation of N-methyl-D-aspartate receptors. Molecular Pharmacology 61:595-605 (2002). [Abstract]

2001

Contractor, A., Swanson, G.T., and Heinemann, S.F.

Kainate receptors are involved in short- and long-term plasticity at mossy fiber synapses in the hippocampus. Neuron 29:209-216 (2001). [Abstract]

Elgoyhen, A.B., Vetter, D.E., Katz, E., Rothlin, C.V., Heinemann, S.F. and Boulter, J.

Alpha 10: A determinant of nicotinic cholinergic receptor function in mammalian vestibular and cochlear mechanosensory hair cells. PNAS 89:3501-3506 (2001). [Abstract]

Pérez-Otaño, I., Schulteis, C.T., Contractor, A., Lipton, S.A., Trimmer, J.S., Sucher, N.J. and Heinemann, S.F.

Assembly with the NR1 subunit is required for surface expression of NR3a-containing NMDA receptors. Journal of Neuroscience 21:1228-1237 (2001). [Abstract]

Sakai, R., Swanson, G.T., Shimamoto, K., Green, T., Contractor, A., Ghetti, A., Tamura-Horikawa, Y., Oiwa, C. and Kamiya, H.

Pharmacological properties of the potent epileptogenic amino acid dysiherbaine, a novel glutamate receptor agonist isolated from the marine sponge Dysidea herbacea. J. Pharm. Exp. Ther. 296:650-658 (2001). [Abstract]

Vissel, B., Royle, G.A., Christie, B.R., Schiffer, H.H., Ghetti, A., Tritto, T. Pérez-Otaño, I., Radcliffe, R.A., Seamans, J., Sejnowski, T., Wehner, J.M., Collins, A.C., O'Gorman, S. and Heinemann, S.F.

The role of RNA editing of kainate receptors in synaptic plasticity and seizures. Neuron 29:217-227 (2001). [Abstract]

Vissel, B., Krupp, J.J., Heinemann, S.F. and Westbrook, G.L.

A use-dependent tyrosine dephosphorylation of NMDA receptors is independent of ion flux. Nature Neuroscience 4:587-596 (2001). [Abstract]

2000

Brené S., Messer C., Okado H., Hartley M., Heinemann S.F., and Nestler E.J.

Regulation of GluR2 promoter activity by neurotrophic factors via a neuron-restrictive silencer element. European Journal of Neuroscience 12(5):1525-1533 (2000). [Abstract]

Contractor, A., Swanson, G.T., Sailer, A., O'Gorman, S., and Heinemann, S.F.

Kainate receptor subunits underlying modulation of excitatory synaptic transmission in the CA3 region of the hippocampus. Journal of Neuroscience 20:8269-8278 (2000). [Abstract]

Ghetti, A. and Heinemann, S.F.

NMDA-dependent modulation of hippocampal kainate receptors by calcineurin and Ca2+/Calmodulin-dependent protein kinase. Journal of Neuroscience 20:2766-2773 (2000). [Abstract]

Katz, E., Verbitsky, M., Rothlin, C.V., Vetter, D.E., Heinemann, S.F., and Elgoyhen, A.B.

High calcium permeability and calcium block of the α9 nicotinic acetylcholine receptor. Hearing Research 141:117-128 (2000). [Abstract]

Mulle, C., Sailer, A., Swanson, G.T., Brana, C., O'Gorman, S., Bettler, B., and Heinemann, S.F.

Subunit composition of kainate receptors in hippocampal interneurons. Neuron 28:475-484 (2000). [Abstract]

Rothlin, C.V., Katz, E., Verbitsky, M., Vetter, D.E., Heinemann, S.F., and Elgoyhen, A.B.

Block of the α9 nicotinic receptor by ototoxic aminoglycosides. Neuropharmacology 39:2525-2532 (2000). [Abstract]

Schiffer, H.H., Swanson, G.T., Masliah, E., and Heinemann, S.F.

Unequal expression of allelic kainate receptor GluR7 mRNAs in human brains. Journal of Neuroscience 20:9025-9033 (2000).
[Abstract]

1999

Alagarsamy, S., Rouse, S.T., Gereau, R.W., IV, Heinemann, S.F., Smith, Y. and Conn, P.J.

Activation of NMDA receptors reverses desensitization of mGluR5 in native and recombinant systems. Nature Neuroscience 2:234-240 (1999). [Abstract]

Bureau, I. Bischoff, S., Heinemann, S.F. and Mulle, C.

Kainate receptor-mediated responses in the CA1 field of wild-type and GluR6-deficient mice. Journal of Neuroscience 19: 653-663 (1999). [Abstract]

Everts, I., Petroski, R., Kizelsztein, P., Teichberg, V.I., Heinemann, S.F. and Hollmann, M.

Lectin-induced inhibition of desensitization of the kainate receptor GluR6 depends on the activation state and can be mediated by a single native or ectopic N-linked carbohydrate side chain. Journal of Neuroscience 19:916-927 (1999). [Abstract]

Krupp, J.J., Vissel, B., Thomas, C.G., Heinemann, S.F. and Westbrook, G.L.

Interactions of calmodulin and alpha-actinin with the NR1 subunit modulates Ca2+-dependent inactivation of NMDA receptors. Journal of Neuroscience 19:1165-1178 (1999). [Abstract]

Sailer, A., Swanson, G.T., Pérez-Otaño, I., O'Leary, L., Malkmus, S.A., Dyck, R.H., Dickinson-Anson, H., Schiffer, H.H., Maron, C., Yaksh, T.L., Gage, F.H., O'Gorman, S. and Heinemann, S.F.

Generation and analysis of GluR5 (Q636R) kainate receptor mutant mice. Journal of Neuroscience 19:8757-8764 (1999). [Abstract]

Schiffer, H.H. and Heinemann, S.F.

A Quantitative Method to Detect RNA Editing Events. Analytical Biochemistry 276: 257-260 (1999). [Abstract]

Somia, N.V., Schmitt, M.J., Vetter, D.E., Van Antwerp, D., Heinemann, S.F. and Verma, I.M.

LFG: An anti-apoptotic gene that provides protection from Fas-mediated cell death. PNAS 96:12667-12672 (1999). [Abstract]

Vetter, D.E., Liberman, M.C., Mann, J., Barhanin, J., Boulter, J., Brown, M.C., Saffiote-Kolman, J., Heinemann, S.F. and Elgoyhen, A.B.

Role of α9 Nicotinic Ach Receptor Subunits in the Development and Function of Cochlear Efferent Innervation. Neuron 23:93-103 (1999). [Abstract]

1998

Contractor, A., Gereau, R.W., IV, Green T. and Heinemann, S.F.

Direct effects of metabotropic glutamate receptor compounds on native and recombinant N-methyl-D-aspartate receptors. PNAS, 95:8969-8974 (1998). [Abstract]

Gereau, R.W., IV and Heinemann, S.F.

Role of protein kinase C phosphorylation in rapid desensitization of metabotropic glutamate receptor 5. Neuron 20:143-151 (1998). [Abstract]

Green, T., Heinemann, S.F. and Gusella, J.F.

Molecular neurobiology and genetics: Investigation of neural function and dysfunction. Neuron 21:427-444 (1998). [Abstract]

Krupp, J.J., Vissel, B., Heinemann, S.F. and Westbrook, G.L.

N-terminal domains in the NR2 subunit control desensitization of NMDA receptors. Neuron 20:317-327 (1998). [Abstract]

Minami, K., Gereau, R.W., IV, Minami, M., Heinemann, S.F. and Harris, R.A.

The effects of ethanol and anesthetics on type 1 and 5 metabotropic glutamate receptors expressed in Xenopus oocytes. Molecular Pharmacology 53:148-156 (1998). [Abstract]

Mulle, C., Sailer, A., Pérez-Otaño, I. Dickinson-Anson, H., Castillo, P.E., Bureau, I., Maron, C., Gage, F.H., Mann, J.R., Bettler, B. and Heinemann, S.F.

Altered synaptic physiology and reduced susceptibility to kainate-induced seizures in GluR6-deficient mice. Nature 391:601-605 (1998). [Abstract]

Swanson, G.T., Green, T. and Heinemann, S.F.

Kainate receptors exhibit differential sensitivities to (S)-5-iodowillardiine. Molecular Pharmacology 53:942-949 (1998). [Abstract]

Swanson, G.T. and Heinemann, S.F.

Heterogeneity of homomeric GluR5 kainate receptor desensitization expressed in HEK293 cells. Journal of Physiology 513:639-646 (1998). [Abstract]