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Publications

2012

248. Development and validation of an automated high-throughput system for zebrafish in vivoscreenings.
Letamendia A., Quevedo C., Ibarbia I., Virto J.M., Holgado O., Diez M., Izpisua Belmonte J.C., Callol-Massot C.
PLoS One. (2012). ePub ahead of print. [link]

249. Generation of induced pluripotent stemcells from human renal proximal tubular cells with only two transcription factors: OCT4 and SOX2
Montserrat, N., Ramírez-Bajo, M.J., Xia, Y., Sancho-Martinez, I., Moya-Rull, , D., Miquel-Serra, L., Yang, S., Nivet, E., Cortina, C., González, F., Izpisua Belmonte, J.C., and Josep M. Campistol
The Journal of Biological Chemistry. (2012). ePub ahead of print. [link]

250. Gating neural development and aging via nuclear pores
Liu, G-H, Li, M., Qu, J., and Izpisua Belmonte, J.C.
Cell Research. (2012). 22:1212-1214. [link]

251. Gametogenesis in a dish
Gu, Y., Liu, G-H, and Izpisua Belmonte, J.C.
Cell Research. (2012). ePub ahead of print. [link]

252. Transient down regulation of Bmp signalling induces extra limbs in vertebrates
Christen, B., Cavaco Rodrigues, A.M., Barragán Monasterio, M., Fabregat Roig, C., and Izpisua Belmonte, J.C.
Development. (2012). 139.2557-2565. [link]

253. Induced neural stem cells: a new tool for studying neural development and neurological disorders
Liu, G-H, Yi, F., Suzuki, K., Qu, J., and Izpisua Belmonte, J.C.
Cell Research. (2012) 22(7):1087-91. [link]

254. Small molecule-mediated TGFβ Type II receptor degradation promotes cardiomyogenesis in embryonic stem cells
Willems, E., Cabral-Teixeira, J., Schade, D., Cai, W., Reeves, P., Bushway, P., Lanier, M., Walsh, C., Kirchhausen, T., Izpisua Belmonte, J.C., Cashman, J., and Mercola, M.
Cell Stem Cell. (2012) In Press. [link]

255. Accumulation of instability in serial differentiation and reprogramming of parthenogenetic human cells
Vassena, R., Montserrat, N., Carrasco Canal, B., Aran, B., de Oñate, L., Veiga, A., and Izpisua Belmonte, J.C.
Human Molecular Genetics. (2012). ePub ahead of print. [link]

256. Human induced pluripotent stem cells derived hepatocytes: rising promise for disease modeling, drug development and celltherapy
Yi, F., Liu, G-H, and Izpisua Belmonte, J.C.
Protein & Cell. (2012) (2012) 3(4): 246–250. [link]

257. Reprogramming based gene therapy for inherited red blood cell disorders
Xu, X., Qu, J., Suzuki, K., Li, M., Zhang, W., Liu, G-H, and Izpisua Belmonte, J.C.
Cell Research. (2012) 22:941-944. [link]

258. Induced pluripotent stem cells in clinical hematology: potentials, progress, and remaining obstacles
Panopoulos, A.D. and Izpisua Belmonte, J.C.
Current Opinion in Hematology. (2012) ) (2012) 19(4):256-60. [link]

259. Rejuvenating liver and pancreas through cell transdifferentiation
Yi, F., Liu, G-H, Izpisua Belmonte, J.C.
Cell Research. (2012) 22:616-619. [link]

260. Cellules Mare Embrionaries: Que en Sabem Despres de Trenta Anys D'Investigacio?
Montserrat, N., Aran, B., and Izpisua Belmonte, J.C.
Treballs de la SCB (2012) 63:215-233. [link]

261. iPS cells versus ES cells: Close enough or yet too far apart?
Bilic, J. and Izpisua Belmonte, J.C.
Stem Cells. (2012) 30:33–41. [link]

262. No factor left behind: generation of transgene free induced pluripotent stem cells.
Li, M. and Izpisua Belmonte, J.C.
American Journal of Stem Cells. (2012). 1(1):75-80. [link]

263. Ablation of Dido3 compromises lineage commitment of stem cells in vitro and during early embryonic development.
Futterer, A., Raya, A., Liorente, M., Izpisua Belmonte, J.C., de la Pompa, J.L., Klatt, P., and Martinez-A, C.
Cell Death and Differentiation. (2012) 19:132-143. [link]

264. Skeletal muscle regeneration in Xenopus tadpoles and zebrafish larvae
Cavaco Rodrigues, A.M., Christen, B., Marti, M., Izpisua Belmonte, J.C.
BMC Developmental Biology. (2012) 12:9. [link]

265. p38α MAPK regulates myocardial regeneration in zebrafish
Jopling, C., Suñè, G., Morera, C., Izpisua Belmonte, J.C.
Cell Cycle. (2012) 11(6):1195-201. [link]

266. Cardiosphere-derived cells for heart regeneration
Masuda, S., Montserrat, N., Okamura, D., Suzuki K., and Izpisua Belmonte, J.C.
The Lancet. (2012). 379(9835): 2425-2426. [link]

267. Cord blood-derived neuronal cells by ectopic expression of Sox2 and c-Myc
Giorgetti, A., Marchetto, M., Li, M., Yu, D., Fazzina, R., Mu, Y., Adamo, A., Paramonov, I., Castaño Cardoso, J., Barragan Monasterio, M., Bardy, C., Cassiani-Ingoni, R. Liu, G-H, Gage F.H., and Izpisua Belmonte, J.C.
PNAS. (2012). ePub ahead of print. [link]

268. Establishment of hepatic and neural differentiation platforms of Wilson's disease specific induced pluripotent stem cells
Yi, F., Qu, J., Suzuki, K., Kim, NY, Liu, G-H, and Izpisua Belmonte, J.C.
Protein & Cell. (2012) ePub ahead of print. [link]

269. DNA Hypermethylation in Somatic Cells Correlates with Higher Reprogramming Efficiency
Barrero MJ, Berdasco M, Paramonov I, Bilic J, Vitaloni M, Esteller M, and Izpisua Belmonte, J.C.
Stem Cells. (2012) ePub ahead of print. [link]

270. Navigating the epigenetic landscape of pluripotent stem cells
Li, M., Liu, G-H, and Izpisua Belmonte, J.C.
Nature Reviews Molecular Cell Biology. (2012) 13, 524-535. [link]

271. Vitrified blastocysts from Preimplantation Genetic Diagnosis (PGD) as a source for human Embryonic Stem Cell (hESC) derivation
Aran, B, Sole, M., Rodriguez-Pizà, I., Parriego, M., Muñoz, Y., Boada, M., Barri, P.N., Izpisua Belmonte, J.C., and Veiga, A.
Journal of Assisted Reproduction and Genetics. (2012) ePub ahead of print. [link]

272. Post-translational modulation of pluripotency
Cai, N., Li, M., Qu, J., Liu, G-H, and Izpisua Belmonte, J.C.
Journal of Molecular Cell Biology. (2012) ePub ahead of print. [link]

273. Huntington’s disease: Dancing in a dish
Zhang, K., Yi, F., Liu, G-H, and Izpisua Belmonte, J.C.
Cell Research. (2012). ePub ahead of print. [link]

274. Lineage conversion methodologies meet the reprogramming toolbox
Sancho-Martinez, I., Baek, S.H., and Izpisua Belmonte, J.C.
Nature Cell Biology. (2012). In Press. [link]

275. The dawn of angiogenesis modeling: regenerating vasculature from human pluripotent stem cells
Yi, F., Qu, J., Liu, G.-H., and Izpisua Belmonte, J.C.
Cell Research. (2012). ePub ahead of print. [link]

276. Identification of a specific reprogramming-associated epigenetic signature in human induced pluripotent stem cells
Ruiz, S., Diep, D., Gore, A., Panopoulos, A.D., Montserrat, N., Plongthongkum, N., Kumar, S., Fung, H.-L., Giorgetti, A., Bilic, J., Batchelder, E.M., Zaehres, H., Kan, N.G.,
Schöler, H.R., Mercola, M., Zhang, K. and Izpisua Belmonte, J.C.
PNAS. (2012). ePub ahead of print. [link]

277. iPSC technology to study human aging and aging-related disorders
Liu, G.-H., Ding, Z., and Izpisua Belmonte, J.C.
Current Opinion in Cell Biology. (2012). ePub ahead of print. [link]

278. Activity of the oral MEK inhibitor trametinib in patients with advanced melanoma: a phase 1 dose-escalation trial
Masuda, S. and Izpisua Belmonte, J.C.
The Lancet Oncology. (2012).13(10): e409. [link]

279. In vitro generation of platelets through direct conversion: first report in My Knowledge (iMK)
Masuda, S., Li, M., and Izpisua Belmonte, J.C.
Cell Research. (2012). ePub ahead of Print. [link]

280. Generation of a drug-inducible reporter system to study cell reprogramming in human cells
Ruiz, S., Panopoulos, A.D., Montserrat, N., Multon, M.-C., Daury, A., Rocher, C.,Spanakis, E., Batchelder, E.M., Orsini, C., Deleuze, J.-F., and Izpisua Belmonte, J.C.
Journal of Biological Chemistry. (2012). ePub ahead of Print. [link]

281. Medicina regenerativa: la revolución de nuestro siglo.
Barrero, M.J. and Izpisua Belmonte, J.C.
Investigacion y Ciencia. (2012). November, 2012. [link]

282. Progressive degeneration of human neural stem cells caused by pathogenic LRRK2
Liu, G.-H., Qu, J., Suzuki, K., Li, M., Montserrat, N., Yi, F., Xu, X., Ruiz, S., Zhang, W., Ren, B., Wagner, U., Kim, A., Li, Y., Goebl, A., Kim, J., Soligalla, R.D., Dubova, I., Thompson, J., Yates, J., Rodriguez Esteban, C., Sancho-Martinez, I. and Izpisua Belmonte, J.C.
Nature. (2012). ePub ahead of print. [link]

283. Neuronopathic Gaucher's Disease: induced pluripotent stem cells for disease modelling and testing chaperone activity of small compounds
Tiscornia, G., Lorenzo Vivas, E., Matalonga, L., Berniakovich, I., Barragán Monasterio, M., Eguizábal Argaiz, C., Gort, L., González, F., Ortiz Mellet, C., García Fernández, J.M., Ribes, A., Veiga, A., and Izpisua Belmonte, J.C.
Human Molecular Genetics. (2012). ePub ahead of print. [link]

284. Beating in a dish: new hopes for cardiomyocyte regeneration
Gu, Y., Yi, F., Liu, G.-H., and Izpisua Belmonte, J.C.
Cell Research. (2012). ePub ahead of print. [link]

285. N-acetylcysteine protects induced pluripotent stem cells from in vitro stress: impact on differentiation outcome
Berniakovich, I., Laricchia-Robbio, L., and Izpisua Belmonte, J.C.
The International Journal of Developmental Biology. (2012). ePub ahead of print. [link]

286. Compound screening platform using human induced pluripotent stem cells to identify small molecules that promote chondrogenesis
Yang, S.-L., Harnish, E., Leeuw, T., Dietz, U., Batchelder, E., Wright, P.S., Peppard, J., August, P., Volle-Challier, C., Bono, F., Herbert, J.-M. and Izpisua Belmonte, J.C.
Protein and Cell. (2012). ePub ahead of print. [link]

287. Hypoxia induces myocardial regeneration in zebrafish
Jopling, C., Suñe, G., Faucherre, A., Fabregat, C. and Izpisua Belmonte, J.C.
Circulation. (2012). 126:3017-3027. [link]

288. Cell cycle gene-specific control of transcription has a critical role in proliferation of primordial germ cells
Okamura, D., Maeda, I., Taniguchi, H., Tokitake, Y., Ikeda, M., Ozato, K., Mise, N., Abe, K., Noce, T., Izpisua Belmonte, J.C., and Matsui, Y.
Genes and Development. (2012). ePub ahead of print. [link]

289. Conversion of human fibroblasts to angioblast-like progenitor cells
Kurian, L., Sancho-Martinez, I., Nivet, E., Aguirre, A., Moon, K., Pendaries, C., Volle-Challier, C., Bono, F., Herbert, J.-M., Pulecio, J., Xia, Y., Li, M., Montserrat, N., Ruiz, S., Dubova, I., Rodriguez, C., Denli, A.M., Boscolo, F.S., Thiagarajan, R.D., Gage, F., Loring, J.F., Laurent, L.C., and Izpisua Belmonte, J.C.
Nature Methods. (2012). ePub ahead of print. [link]

290. Reprogramming development and aging: cell differentiation as a malleable process
Izpisua Belmonte, J.C.
Current Opinion in Cell Biology. (2012). ePub ahead of print. [link]