Salk Home | Faculty | Laboratories

Publications

2011

207. Dynamic Changes in the Copy Number of Pluripotency and Cell Proliferation Genes in Human ES and iPS Cells during Reprogramming and Time in Culture.
Laurent, L.C., Ulitsky, I., Slavin, I., Tran, H., Schork, A., Morey, R., Lynch, C., Harness, J., Lee, S., Barrero, M.J., Martynova, M., Muller, F.-J., Semechkin, R., Galat, V., Gottesfeld, J., Izpisua Belmonte, J.C., Murray, C., Keirstead, H., Park, H.-S., Schmidt, U., Laslett, A., Nievergelt, C., Shamir, R. and Loring, J.
Cell Stem Cell. (2011) 8:106-118. [link]

208. Dedifferentiation, transdifferentiation and reprogramming: three routes to regeneration.
Jopling, C., Boue, S. and Izpisua Belmonte, J.C.
Nature Reviews Molecular Cell Biology. (2011) 12:79-89. [link]

209. Cell fate conversion by mRNA.
Li, M., Sancho-Martinez, I. and Izpisua Belmonte, J.C.
Stem Cell Research and Therapy. (2011) 2:5. [link]

210. Cre-LoxP-regulated expression of monoclonal antibodies driven by an ovalbumin promoter in primary oviduct cells.
Oishi, I., Kim, S., Yoshii, K., Rodriguez Esteban, C. and Izpisua Belmonte, J.C.
BMC Biotechnology. (2011) 11:5. [link]

211. A high proliferation rate is required for cell reprogramming and maintenance of human embryonic stem cell identity.
Ruiz, S., Panopoulos, A.D., Herrerias, A., Bissig, K-D, Lutz, M., Berggren, W.T., Verma, I. and Izpisua Belmonte, J.C.
Current Biology. (2011) 21: 45-52. [link]

212. Somatic coding mutations in human induced pluripotent stem cells.
Gore, A., Li, Z., Fung, H.L., Young, J., Agarwal, S., Antosiewicz-Bourget, J., Canto, I., Giorgetti, A., Israel, M., Kiskinis, E., Lee, J.H., Loh, Y.H., Manos, P.D., Montserrat, N., Panopoulos, A.D., Ruiz, S., Wilbert, M., Yu, J., Kirkness, E.F., Izpisua Belmonte, J.C., Rossi, D.J., Thomson, J., Eggan, K., Daley, G.Q., Goldstein, L.S.B. and Zhang, K.
Nature. (2011) 471:46-7. [link]

213. Regenerating the Epigenome.
Barrero, M.J. and Izpisua Belmonte, J.C.
EMBO Reports. (2011) 12:208-215. [link]

214. Modelling Long QT Syndrome with iPS cells: Be still, my beating heart...
Tiscornia, G., Montserrat, N. and Izpisua Belmonte, J.C.
Circulation Research. (2011) 108:648-649. [link]

215. Simple generation of human induced Pluripotent stem cells using Poly({beta}-Amino Esters) as non-viral gene delivery system.
Montserrat, N., Garreta Bahima, E., Gonzalez, F., Gutierrez, J., Eguizabal, C., Ramos Perez, V., Borros, S., Izpisua Belmonte, J.C.
Journal of Biological Chemistry. (2011) 286:12417-28. [link]

216. Methods for making iPS cells: reprogramming à la carte.
Gonzalez, F., Boue, S. and Izpisua Belmonte, J.C.
Nature Reviews Genetics. (2011) 12:231-242. [link]

217. iPSCs: Induced Back to Controversy.
Panopoulos, A., Ruiz, S. and Izpisua Belmonte, J.C.
Cell Stem Cell. (2011) 8:347-348. [link]

218. iPS cells forgive but do not forget.
Barrero, M.J. and Izpisua Belmonte, J.C.
Nature Cell Biology. (2011) 13:523–525. [link]

219. Recapitulation of premature ageing with iPSCs from Huchinson-Gilford progeria syndrome.
Liu, G-H, Barkho, B.Z., Ruiz, S., Diep, D., Qu, J., Yang, S-L, Panopoulos, A.D., Suzuki, K., Kurian, L., Walsh, C., Thompson, J., Boue, S., Fung, H.L., Sancho-Martinez, I., Zhang, K., Yates III, J. and Izpisua Belmonte, J.C.
Nature. (2011) 472:221-5. [link]

220. Rapid and highly efficient generation of induced pluripotent stem cells from human umbilical vein endothelial cells.
Panopoulos, A., Ruiz, S., Yi, F., Herrerias, A., Batchelder, E.M. and Izpisua Belmonte, J.C.
PLoS ONE. (2011) 6:e19743. [link]

221. Human cord blood reprogrammed into embryonic-like stem cells.
Giorgetti, A., Fazzina, R., Li, M. and Izpisua Belmonte, J.C.
ISBT Science Series. (2011) 6:107-111. [link]

222. The cell cycle inhibitor p27Kip1 controls self-renewal and pluripotency of human embryonic stem cells by regulating the cell cycle, Brachyury and Twist.
Menchon, C., Edel, M. and Izpisua Belmonte, J.C.
Cell Cycle. (2011) 10:1435-1447. [link]

223. A protocol to assess cell cycle and apoptosis in human and mouse pluripotent cells.
Edel, M., Menchon, C., Andres Vacquero, J.M. and Izpisua Belmonte, J.C.
Cell Communication and Signaling. (2011) 9:8 [link]

224. Disease correction, the iPSC way. Advances in iPSC-based therapy.
Sancho-Martinez, I., Li, M. and Izpisua Belmonte, J.C.
Clinical Pharmacology and Therapeutics. (2011) 89:746-749. [link]

225. Targeted Gene Correction of Laminopathy-Associated LMNA Mutations in Patient-Specific iPSCs.
Liu, G-H, Suzuki, K., Qu, J., Sancho-Martinez, I., Yi, F., Li, M., Kumar, S., Nivet, E., Kim, J., Soligalla, R.D., Dubova, I., Goebl, A., Plongthongkum, N., Fung, H.L., Zhang, K., Loring, J.F., Laurent, L.C., Izpisua Belmonte, J.C.
Cell Stem Cell. (2011) 8:688-694. [link]

226. LSD1 regulates the balance between self-renewal and differentiation in human embryonic stem cells.
Adamo, A., Sese, B., Boue, S., Castano, J., Paramonov, I., Barrero, M.J. and Izpisua Belmonte, J.C.
Nature Cell Biology. (2011) 13:652-660. [link]

227. Complete meiosis from human induced pluripotent stem cells.
Eguizabal, C., Montserrat, N., Vassena, R., Barragan, M., Garreta, E., Garcia-Quevedo, L., Vidal, F., Giorgetti, A., Veiga, A. and Izpisua Belmonte, J.C.
Stem Cells. (2011) 29:1186-1195. [link]

228. Pluripotency of Male Germline Stem Cells.
Kim, S. and Izpisua Belmonte, J.C.
Molecules and Cells. (2011) March 24 Epub Ahead of Print. [link]

229. Efficient Generation of Hematopoietic Precursors and Progenitors from Human Pluripotent Stem Cell Lines.
Woods, N-B, Parker, A.S., Moraghebi, R., Lutz, M.K., Firth, A.L., Brennand, K.J., Berggren, W.T., Raya, A., Izpisua Belmonte, J.C., Gage, F.H. and Verma, I.M.
Stem Cells. (2011) 29:1158–1164. [link]

230. Study of pluripotency markers in zebrafish embryos and transient ES cell cultures.
Robles, V., Marti, M. and Izpisua Belmonte, J.C.
Zebrafish. (2011) 8:57-63. [link]

231. Waves of early transcriptional activation and pluripotency program initiation during human preimplantation development.
Vassena, R., Boue, S., Gonzalez Roca, E., Aran, B., Auer, H., Veiga, A., and Izpisua Belmonte, J.C.
Development. (2011) 138:3699-3709. [link]

232. Anaerobicizing into Pluripotency.
Panopoulos, A.D. and Izpisua Belmonte, J.C.
Cell Metabolism. (2011) 14:143-4. [link]

233. A Src-Tks5 Pathway Is Required for Neural Crest Cell Migration during Embryonic Development.
Murphy, D.A., Diaz, B., Bromann, P.A., Tsai, J.H., Kawakami, Y., Maurer, J., Stewart, R.A., Izpisua Belmonte, J.C., and Courtneidge, S.A.
PLoS ONE. (2011) 6:e22499. [link]

234. Islet1-mediated activation of the ß-catenin pathway is necessary for hindlimb initiation in mice.
Kawakami, Y., Marti, M., Kawakami, H., Itoh, J., Quach, T., Johnson, A., Sahara, S., O'Leary, D.D.M., Nakagawa, Y., Lewandoski, M., Pfaff, S., Evans, S., and Izpisua Belmonte, J.C.
Development. (2011) 138:4465-4473. [link]

235. Diseases in a Dish: modeling human genetic disorders using induced pluripotent cells.
Tiscornia, G. and Izpisua Belmonte, J.C.
Nature Medicine. (2011) In Press.

236. LSD1 and Pluripotency: A new player in the network.
Adamo, A., Barrero, M.J. and Izpisua Belmonte, J.C.
Cell Cycle. (2011) 10:3215-3216. [link]

237. Efficient Generation of A9 Midbrain Dopaminergic Neurons by Lentiviral Delivery of LMX1A in Human Embryonic Stem Cells and iPS Cells.
Sanchez-Danes A., Consiglio A., Richaud Y., Rodríguez-Pizà I., Dehay B., Edel M., Bové J., Memo M., Vila M., Raya A., and Izpisua Belmonte J.C.
Human Gene Therapy. (2011) 22:1 [link]

238. The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming.
Panopoulos, A.D., Yanes, O., Ruiz, S., Kida, Y.S., Diep, D., Tautenhahn, R., Herrerias, A., Batchelder, E.M., Plongthongkum, N., Lutz, M., Berggren, W.T., Zhang, K., Evans, R.M., Suizdak, G., and Izpisua Belmonte, J.C.
Cell Research. (2011) 22(1):168-77. [link]

239. Histone H1 variants are differentially expressed and incorporated into chromatin during differentiation and reprogramming to pluripotency.
Terme, J.-M., Sese, B., Millan-Ariño, L., Mayor, R., Izpisua Belmonte, J.C., Barrero, M.J., and Jordan, A.
Journal of Biological Chemistry. (2011)  286:35347–35357. [link]

240. Efficient correction of hemoglobinopathy-causing mutations by homologous recombination in integration-free patient iPSCs
Li, M., Suzuki, K., Qu, J., Saini, P., Dubova, I., Yi, F., Lee, J., Sancho-Martinez, I., Liu, G-H, and Izpisua Belmonte, J.C.
Cell Research. (2011) ePub ahead of print November 22, 2011. [link]

241. Identification of Phosphorylase Kinase as a Novel Therapeutic Target through High-throughput Screening for Anti-angiogenesis Compounds in Zebrafish
Camus, S., Quevedo, C., Menendez, S., Paramonov, I., Stouten, P., Janssen, R., Rueb, S., He, S., Snaar-Jagalska, E., Laricchia-Robbio, L., and Izpisua Belmonte, J.C.
Oncogene (2011) ePub ahead of print December 19, 2011. [link]

242. Cut and Paste: restoring cellular function by gene correction
Liu, G-H, Sancho-Martinez, I., and Izpisua Belmonte, J.C.
Cell Research. (2011) ePub ahead of print December 6, 2011. [link]

243. The labyrinth of nuclear reprogramming
Sancho-Martinez, I., Nivet, E., and Izpisua Belmonte, J.C.
Journal of Molecular Cell Biology. (2011) ePub ahead of print November 16, 2011. [link]

244. Increased dosage of tumor suppressors limits the tumorigenicity of iPS cells without affecting their pluripotency
Menendez, S., Camus, S., Herreria, A., Paramonov, I., Batlle Morera, L., Collado, M., Pekarik, V., Maceda, I., Edel, M., Consiglio, A., Sanchez, A., Li, H., Serrano, M. and Izpisua Belmonte, J.C.
Aging Cell. (2011). ePub ahead of print November 10, 2011. [link]

245. Chapter 9: Induced pluripotent stem cells from cord blood CD133+ cells using Oct4 and Sox2.
Giorgetti, A., Montserrat, N. and Izpisua Belmonte, J.C.
Lineage-Specific Differentiation of Human Embryonic and Induced Pluripotent Stem Cells Methods and Protocol. (2011) Springer Protocol Handbook Series.

246. Chapter 15: Retroviral-vector based approaches for the generation of human induced pluripotent stem cells from fibroblasts and keratinocytes.
Panopoulos, A., Ruiz, S. and Izpisua Belmonte, J.C.
Lineage-Specific Differentiation of Human Embryonic and Induced Pluripotent Stem Cells Methods and Protocol. (2011) Springer Protocol Handbook Series.

247. Plucked hair: how to get stem cells and induced pluripotent stem cells for future clinical applications.
Montserrat, N. and Izpisua Belmonte, J.C.
Handbook of Hair in Health and Disease. (2011) Wageningen Academic Publishers.