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|Discovery of brain's natural resistance to drugs may offer clues to treating addiction http://www.salk.edu/news/pressrelease_details.php?press_id=546|
The left image shows GABA inhibitory neurons (labeled green) in the brain's reward pathway.
The right panel shows electrical activity of GABA inhibitory neuron in a Saline-injected or methamphetamine (METH)-injected mouse.
Activation of the GABA type B receptor normally silences electrical activity, but has no effect in a mouse 24 hours after a single injection of methamphetamine Image: Courtesy of Kelly Tan and Claire Padgett, Salk Institute for Biological Studies
Michaelanne Munoz, UCSD graduate student and Paul Slesinger, Associate Professor, Clayton Foundation Laboratories for Peptide Biology. Image: Courtesy of the Salk Institute for Biological Studies