Salk Institute
Helmsley Center for Genomic Medicine
Publications

Sun H, Liu Y, and Hunter, T. Multiple Arkadia/RNF111 Structures Coordinate its Polycomb Body Association and Transcriptioinal Control. MolCellBio (2014).

Ahmadian M, Suh JM, Hah N, Liddle C, Atkins AR, Downes M, Evans RM.  (2013) PPARγ signaling and metabolism: the good, the bad and the future.  Nat Med. 2013 May;19(5):557-66. doi: 10.1038/nm.3159. Epub 2013 May 7. Review.  PMCID: 3870016

d’Uscio LV, He T, Santhanam AVR, Tai L-J, Evans RM, Katusic ZS. (2013) Mechanisms of vascular dysfunction in mice with endothelium-specific deletion of PPARdelta gene.  Am J Physiol Heart Circ Physiol. 2014 Jan 31. doi: 10.1152/ajpheart.00761.2013 [Epub ahead of print]  PMID: 24486511  NIHMSID 566372

Ding N, Liddle C, Evans RM, Downes M. (2013)  Hepatic actions of vitamin D receptor ligands: a sunshine option for chronic liver disease?  Expert Rev Clin Pharmacol. 2013 Nov;6(6):597-9. doi: 10.1586/17512433.2013.841078.  PMID: 24164608

Du L, Bergsneider M, Mirsadraei L, Young SH, Jonker JW, Downes M, Yong WH, Evans RM, Heaney AP(2013)  Evidence for orphan nuclear receptor TR4 in the etiology of Cushing disease. Proc Natl Acad Sci U S A. 2013 May 21; 110(21): 8555–8560. Published online 2013 May 7. doi: 10.1073/pnas.1306182110. PMCID: 3666748

Evans RM, Mangelsdorf DJ. (2014)  Nuclear Receptors, RXR & the Big Bang.  Cell.  In Press.  NIHMSID: 578607

Fan W, Atkins AR , Yu RT, Downes M, Evans RM.  (2013)  Road to Exercise Mimetics: Targeting Nuclear Receptors in Skeletal Muscle. Journal of Molecular Endocrinology  PMID: 24280961

Firth, AL,  Dargitza, CT, Quallsa, SJ,  Menona,T,  Wright,R,   Singera, O,  Gage FH,  Khannab, A, and Verma, IM. (2014) 1Generation of multiciliated cells in functional airway epithelia from human induced pluripotent stem cells.  PNAS (Epub, March 24).

Friedmann-Morvinski D and Verma I. (2014) Dedifferentiation and reprogramming: origins of cancer stem cells.  EMBO Reports (Review) 1-10.

Goodwin, J., Svensson, R.U., Stein, B., Ross, D. and Shaw, R.J. (2014) Lkb1 suppresses cell migration and invasion through Dixdc1. Mol Cell. [in press]    

Havlicek S, Kohl Z, Mishra HK, Prots I, Eberhardt E, Denguir N, Wend H, Plötz S,  Boyer L, Marchetto MC, Aigner S, Sticht H, Groemer TW, Hehr, Lampert A,  Schlötzer-Schrehardt U, Winkler J, Gage FH, Winner B.  (2014) “Gene dosage-dependent rescue of HSP neurite defects in SPG4 patients’ neurons.” Hum Mol Genet.

Hong S, Ahmadian M, Yu RT, Atkins AR, Downes M, Evans RM.  (2014)  Nuclear receptors and metabolism: from feast to famine.  Diabetologia. PMID: 24619218

Hong S, Dvorak-Ewell M, Stevens HY, Barish GD, Castro GL, Nofsinger R, Frangos JA, Shoback D, Evans RM.  (2013) Rescue of a Primary Myelofibrosis Model by Retinoid-Antagonist Therapy.  Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):18820-5. doi: 10.1073/pnas.1318974110. Epub 2013 Nov 4.  PMCID: 3839709

Hrvoj-Mihic BM, Marchetto C, Gage FH, Semendeferi K, Muotri AR. (2013) "Novel Tools, Classic Techniques: Evolutionary Studies Using Primate Pluripotent Stem Cells." Biol Psychiatry.

Kuria, LI, Sancho-Martinez E, Nivet A, Aguirre K, Moo C., Pendaries C, Volle-Challier C, Bono F, Herbert,JM, Pulecio Y, Xia M, Li N, Montserrat S, Ruiz S, Dubova I, Rodriguez C, Denli AM, Boscolo FS, Thiagarajan, RD,  Gage FH,   Loring JF, Laurent LC, and  Izpisua Belmonte, JC. (2013) "Conversion of Human Fibroblasts to Angioblast-Like Progenitor Cells." Nat Methods 10, no. 1 77-83.

Lam MT, Cho H, Lesch HP, Gosselin D, Heinz S, Tanaka-Oishi Y, Benner C, Kaikkonen MU, Kim AS, Kosaka M, Lee CY, Watt A, Grossman TR, Rosenfeld MG, Evans RM, Glass CK. (2013)  Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription. Nature. 2013 Jun 27;498(7455):511-5. doi: 10.1038/nature12209. Epub 2013 Jun 2. PMCID:  3839578 

Liang Y, Franks TM, Marchetto MC, Gage FH. (2013) Hetzer MW. Dynamic Association of NUP98 with the Human Genome. PLoS Genet. 9(2):e1003308.

Liu S, Evans RM. (2014) Tick, tock, a high-fat clock.  Nature Review Endocrinology. Nature Reviews Endocrinology 10, 191–192 (2014) doi:10.1038/nrendo.2014.23.  Published online 04 March 2014  PMID: 24590185

Marchetto MC, Narvaiza I, Denli AM, Benner C, Lazzarini TA, Nathanson JL, Paquola AC, Desai KN, Herai RH, Weitzman MD, Yeo GW, Muotri AR, and Gage FH. (2013) "Differential L1 Regulation in Pluripotent Stem Cells of Humans and Apes." Nature.

McConnell MJ, Lindberg MR, Brennand KJ, Piper JC, Voet T, Cowing-Zitron C, Shumilina S, Lasken RS, Vermeesch J, Hall IM, Gage FH. (in press) Mosaic Copy Number Variation in Human Neurons. Science.

Mochiroud L, Eichner L, Shaw R,  Auwerx J. (2014) Transcriptional coregulators: fine-tuning metabolism. Cell Metab.

Shackelford DB, Abt E, Gerken L, Vasquez DS, Atsuko S, Leblanc M, Wei L, Fishbein MC, Czernin J, Mischel PS, Shaw RJ. (2013) LKB1 inactivation dictates therapeutic response of non-small cell lung cancer to the metabolism drug phenformin. Cancer Cell 23:143-158. PMCID: PMC3579627    

Uhlenhaut NH, Barish GD, Yu RT, Downes M, Karunasiri M, Liddle C, Schwalie P, Hübner N, Evans RM.  (2013) Insights into Negative Regulation by the Glucocorticoid Receptor from Genome-wide Profiling of Inflammatory Cistromes.  Mol Cell. 2013 Jan 10;49(1):158-71. doi: 10.1016/j.molcel.2012.10.013. Epub 2012 Nov 15.  PMCID:  3640846

Wright R, Réthelyi JM, Gage FH. (2014)“Enhancing Induced Pluripotent Stem Cell Models of Schizophrenia.” JAMA Psychiatry

Yu DX, Di Giorgio FP, Yao J, Marchetto MC, Brennand K, Wright R, Mei A, McHenry L, Lisuk D, Grasmick JM, Silberman P, Silberman G, Jappelli R, Gage FH. (2014) "Modeling Hippocampal Neurogenesis Using Human Pluripotent Stem Cells." Stem Cell Reports 2, no. 3 295-310.

Zhao X, Cho H, Yu RT , Atkins AR, Downes M, Evans RM (2014).  Nuclear Receptors Rock around the Clock.  EMBO.  PMID: 24737872


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