Salk Institute

Technologies Available for Licensing

Method of Increasing Growth and Yield in Plants (Cyclin)

Inventors: Christopher Lamb, Peter Doerner
Potential Uses: Plant Biology, Agriculture, Horticulture, Forestry
CYC1 Cyclin gene, which promotes increased root mass, shoot and fruit growth

The invention provides a method of producing a genetically modified plant characterized as having increased growth and yield compared to the corresponding wild-type plant. The method comprises contacting plant cells with nucleic acid encoding a cyclin protein, to obtain transformed plant cells; producing plants from the transformed plant cells; and selecting a plant exhibiting increased yield. The cyclin-encoding nucleic acid encodes the cyclin cyc1aAt. Modified expression of the CYC1 gene has been shown to enhance plant growth through accelerating development. By providing a larger root mass, the CYC1 gene can accelerate the overall growth of plants, as in the case of trees grown under water-limiting conditions. In addition, the CYC1 gene can be selectively targeted to other plant organs such as fruit, to increase sink strength and hence fruit yield. The manipulation of this gene has broad applications to a variety of markets, such as the forest product industry as well as cereal, fruit and vegetable production.

Salk No: S96006
Patent Status: U.S. Patent No. 6,252,139 issued June 26, 2001
U.S. Patent No. 6,696,623 issued February 24, 2004
Publications: Nature 380(6574):520-3 (April 1996)
License Terms: Non-exclusive and Exclusive in Field of Use Licenses Negotiable
Contact: Michelle Booden, Ph.D., Director of Licensing, 858.453.4100 x1612,

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