Salk Institute

Shared NCI Cancer Center Council (C3) Cores

Shared NCI Cancer Center Council (C3) cores

The following NCI basic and comprehensive cancer center supported core resources located at neighboring academic institutions are available to all Salk Institute Cancer Center members.

Recharge rates at these centers have been negotiated to be equal to the host institutions cancer center member internal rate plus 16% indirect cost.

UC San Diego Moores Cancer Center
The Biorepository Core is a developing collection of plasma, serum, RNA stabilized buffy coat, urine, viable tumor samples, and formalin-fixed paraffin-embedded tumor; with associated clinical information. The tumor collection is predominately from breast and gastrointestinal malignancies. The core can provide anonymized samples from the repository, or ongoing sample collection.

Salk Institute Cancer Center
Gene Transfer, Targeting and Therapeutics Core (GT3) in the Salk Institute Cancer Center provides expert consultation for the safe and effective use of viral vector technologies, and offers custom design and production services for multiple viral vector types. The core supports production of custom lentiviral, retroviral, rAAV, G-deleted rabies, and adenoviral vectors.

Sanford-Burnham Cancer Center
The Chemical Library Screening Core includes the Assay Development, Chemical Libraries & High-Throughput Screening, and High Content Screening facilities. Support is provided for development and optimization of robust high throughput-ready assays (384 or 1536 well) with a wide variety of readouts, with emphasis on optimal formulation of the assays for increased sensitivity in identification of hits. High throughput screening is performed using the core's focused libraries or broad collections of compounds (>800,000 compounds total), and extensive robotics. The High Content Screening Facility develops assays for screening with high-throughput microscopy, and assists with sample preparation, image acquisition, pilot and full-scale screens, high content data analysis and management, and algorithm development. These cores are part of the integrated chemical biology and drug discovery efforts in Sanford-Burnham's Conrad Prebys Center.

San Diego NCI Cancer Center Council

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