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Wolfgang Fischer
Staff Scientist
Clayton Foundation Laboratories fo Peptide Biology
In addition to his research projects, Dr. Fischer directs the Vincent J. Coates Foundation Center for Mass Spectrometry at the Salk Institute. The Center employs state-of-the-art mass spectrometry to identify proteins involved in biological processes. Besides protein identification, the characterization of posttranslational modifications is a major research focus.
Education
- Ph.D., Biochemistry, RWTH Aachen, Germany
- Postdoctoral Fellow, The Salk Institute, La Jolla
Awards and Honors
- Ph.D. Fellowship, German National Merit Foundation
- Borchers Medal, RWTH Aachen
- Postdoctoral Fellowship, Boehringer Ingelheim Foundation
Selected Publications
- Low W, Kang J, DiGruccio M, Kirby D, Perrin M, Fischer WH: MALDI-MS Analysis of Peptides Modified with Photolabile Arylazido Groups. J. Am. Soc. Mass Spectrom. 2004, 15:1156-1160.
- Harrison CA, Gray PC, Fischer WH, Donaldson C, Choe S, Vale W: An activin mutant with disrupted ALK4 binding blocks signaling via type II receptors. J Biol Chem 2004, 279:28036-28044.
- Cumming RC, Andon NL, Haynes PA, Park M, Fischer WH, Schubert D: Protein Disulfide Bond Formation in the Cytoplasm during Oxidative Stress. J Biol Chem 2004, 279:21749-21758.
- Fischer WH, Park M, Donaldson C, Wiater E, Vaughan J, Bilezikjian LM, Vale W: Residues in the C-terminal region of activin A determine specificity for follistatin and type II receptor binding. J. Endocrinol. 2003, 176:61-68.